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Splign is a utility for computing cDNA-to-Genomic,
or spliced sequence alignments.
At the heart of the program is a global alignment algorithm
that specifically accounts for introns and splice signals.
It is due to this algorithm that Splign is accurate
in determining splice sites and tolerant to sequencing errors.
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On the other side of the tool are Blast post-processing routines.
Splign uses Blast hits to identify possible locations
of genes and their duplications on genomic sequences and
then to speed up the core dynamic programming.
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Please follow one of the links below or
navigate using the menu bar at the top of this page.
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Reference:
Yu.Kapustin, A.Souvorov, T.Tatusova.
Splign - a Hybrid Approach To Spliced Alignments.
RECOMB 2004 - Currents in Computational Molecular Biology. p.741.
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