My Bibliography

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A point-of-care assay for alpha-1-acid glycoprotein as a diagnostic tool for rapid, mobile-based determination of inflammation. Current research in biotechnology. . NIHMSID: NIHMS1566385.doi: 10.1016/j.crbiot.2019.09.002.

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Brown AM, Willetts NS. A physical and genetic map of the IncN plasmid R46. Plasmid. 1981 Mar;5(2):188-201. doi: 10.1016/0147-619x(81)90020-2. PubMed PMID: 6264522.

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Brown AM, Coupland GM, Willetts NS. Characterization of IS46, an insertion sequence found on two IncN plasmids. J Bacteriol. 1984 Aug;159(2):472-81. doi: 10.1128/jb.159.2.472-481.1984. PubMed PMID: 6086571; PubMed Central PMCID: PMC215669.

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Westley B, May FE, Brown AM, Krust A, Chambon P, Lippman ME, Rochefort H. Effects of antiestrogens on the estrogen-regulated pS2 RNA and the 52- and 160-kilodalton proteins in MCF7 cells and two tamoxifen-resistant sublines. J Biol Chem. 1984 Aug 25;259(16):10030-5. PubMed PMID: 6469952.

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Brown AM, Jeltsch JM, Roberts M, Chambon P. Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7. Proc Natl Acad Sci U S A. 1984 Oct;81(20):6344-8. doi: 10.1073/pnas.81.20.6344. PubMed PMID: 6593703; PubMed Central PMCID: PMC391920.

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Fung YK, Shackleford GM, Brown AM, Sanders GS, Varmus HE. Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene. Mol Cell Biol. 1985 Dec;5(12):3337-44. doi: 10.1128/mcb.5.12.3337-3344.1985. PubMed PMID: 3018519; PubMed Central PMCID: PMC369161.

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Brown AM, Wildin RS, Prendergast TJ, Varmus HE. A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line. Cell. 1986 Sep 26;46(7):1001-9. doi: 10.1016/0092-8674(86)90699-9. PubMed PMID: 3019559.

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Jeltsch JM, Roberts M, Schatz C, Garnier JM, Brown AM, Chambon P. Structure of the human oestrogen-responsive gene pS2. Nucleic Acids Res. 1987 Feb 25;15(4):1401-14. doi: 10.1093/nar/15.4.1401. PubMed PMID: 3822834; PubMed Central PMCID: PMC340557.

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Rodland KD, Brown AM, Magun BE. Individual mouse VL30 elements transferred to rat cells by viral pseudotypes retain their responsiveness to activators of protein kinase C. Mol Cell Biol. 1987 Jun;7(6):2296-8. doi: 10.1128/mcb.7.6.2296-2298.1987. PubMed PMID: 3600664; PubMed Central PMCID: PMC365355.

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Coupland GM, Brown AM, Willetts NS. The origin of transfer (oriT) of the conjugative plasmid R46: characterization by deletion analysis and DNA sequencing. Mol Gen Genet. 1987 Jun;208(1-2):219-25. doi: 10.1007/BF00330445. PubMed PMID: 3039307.

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Papkoff J, Brown AM, Varmus HE. The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway. Mol Cell Biol. 1987 Nov;7(11):3978-84. doi: 10.1128/mcb.7.11.3978-3984.1987. PubMed PMID: 3323883; PubMed Central PMCID: PMC368066.

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Brown AM, Papkoff J, Fung YK, Shackleford GM, Varmus HE. Identification of protein products encoded by the proto-oncogene int-1. Mol Cell Biol. 1987 Nov;7(11):3971-7. doi: 10.1128/mcb.7.11.3971-3977.1987. PubMed PMID: 2828922; PubMed Central PMCID: PMC368065.

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Bradley RS, Brown AM. The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix. EMBO J. 1990 May;9(5):1569-75. doi: 10.1002/j.1460-2075.1990.tb08276.x. PubMed PMID: 2158444; PubMed Central PMCID: PMC551851.

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Mikawa T, Fischman DA, Dougherty JP, Brown AM. In vivo analysis of a new lacZ retrovirus vector suitable for cell lineage marking in avian and other species. Exp Cell Res. 1991 Aug;195(2):516-23. doi: 10.1016/0014-4827(91)90404-i. PubMed PMID: 2070832.

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Koo HM, Brown AM, Ron Y, Dougherty JP. Spleen necrosis virus, an avian retrovirus, can infect primate cells. J Virol. 1991 Sep;65(9):4769-76. doi: 10.1128/JVI.65.9.4769-4776.1991. PubMed PMID: 1870201; PubMed Central PMCID: PMC248934.

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Jue SF, Bradley RS, Rudnicki JA, Varmus HE, Brown AM. The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells. Mol Cell Biol. 1992 Jan;12(1):321-8. doi: 10.1128/mcb.12.1.321-328.1992. PubMed PMID: 1530877; PubMed Central PMCID: PMC364112.

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Mikawa T, Borisov A, Brown AM, Fischman DA. Clonal analysis of cardiac morphogenesis in the chicken embryo using a replication-defective retrovirus: I. Formation of the ventricular myocardium. Dev Dyn. 1992 Jan;193(1):11-23. doi: 10.1002/aja.1001930104. PubMed PMID: 1540702.

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Koo HM, Brown AM, Kaufman RJ, Prorock CM, Ron Y, Dougherty JP. A spleen necrosis virus-based retroviral vector which expresses two genes from a dicistronic mRNA. Virology. 1992 Feb;186(2):669-75. doi: 10.1016/0042-6822(92)90033-l. PubMed PMID: 1310190.

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Eisenberg LM, Ingham PW, Brown AM. Cloning and characterization of a novel Drosophila Wnt gene, Dwnt-5, a putative downstream target of the homeobox gene distal-less. Dev Biol. 1992 Nov;154(1):73-83. doi: 10.1016/0012-1606(92)90049-m. PubMed PMID: 1358729.

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Ramakrishna NR, Brown AM. Wingless, the Drosophila homolog of the proto-oncogene Wnt-1, can transform mouse mammary epithelial cells. Dev Suppl. 1993;:95-103. PubMed PMID: 8049493.

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Stocker KM, Brown AM, Ciment G. Gene transfer of lacZ into avian neural tube and neural crest cells by retroviral infection of grafted embryonic tissues. J Neurosci Res. 1993 Jan;34(1):135-45. doi: 10.1002/jnr.490340114. PubMed PMID: 8380875.

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Dealy CN, Roth A, Ferrari D, Brown AM, Kosher RA. Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes. Mech Dev. 1993 Oct;43(2-3):175-86. doi: 10.1016/0925-4773(93)90034-u. PubMed PMID: 8297789.

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Bradley RS, Cowin P, Brown AM. Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. J Cell Biol. 1993 Dec;123(6 Pt 2):1857-65. doi: 10.1083/jcb.123.6.1857. PubMed PMID: 8276903; PubMed Central PMCID: PMC2290857.

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Epstein ML, Mikawa T, Brown AM, McFarlin DR. Mapping the origin of the avian enteric nervous system with a retroviral marker. Dev Dyn. 1994 Nov;201(3):236-44. doi: 10.1002/aja.1002010307. PubMed PMID: 7881127.

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Herzlinger D, Qiao J, Cohen D, Ramakrishna N, Brown AM. Induction of kidney epithelial morphogenesis by cells expressing Wnt-1. Dev Biol. 1994 Dec;166(2):815-8. doi: 10.1006/dbio.1994.1360. PubMed PMID: 7813799.

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Ferrari D, Sumoy L, Gannon J, Sun H, Brown AM, Upholt WB, Kosher RA. The expression pattern of the Distal-less homeobox-containing gene Dlx-5 in the developing chick limb bud suggests its involvement in apical ectodermal ridge activity, pattern formation, and cartilage differentiation. Mech Dev. 1995 Aug;52(2-3):257-64. doi: 10.1016/0925-4773(95)98113-o. PubMed PMID: 8541214.

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Bradley RS, Brown AM. A soluble form of Wnt-1 protein with mitogenic activity on mammary epithelial cells. Mol Cell Biol. 1995 Aug;15(8):4616-22. doi: 10.1128/MCB.15.8.4616. PubMed PMID: 7623853; PubMed Central PMCID: PMC230702.

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Bergstein I, Schultz R, Osborne MP, Welcsh PL, Bowcock AM, Brown AM. Investigation of the possible role of WNT genes in human breast cancer. Ann N Y Acad Sci. 1995 Sep 30;768:257. doi: 10.1111/j.1749-6632.1995.tb12134.x. PubMed PMID: 8526360.

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Stern HM, Brown AM, Hauschka SD. Myogenesis in paraxial mesoderm: preferential induction by dorsal neural tube and by cells expressing Wnt-1. Development. 1995 Nov;121(11):3675-86. doi: 10.1242/dev.121.11.3675. PubMed PMID: 8582280.

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Rudnicki JA, Brown AM. Inhibition of chondrogenesis by Wnt gene expression in vivo and in vitro. Dev Biol. 1997 May 1;185(1):104-18. doi: 10.1006/dbio.1997.8536. PubMed PMID: 9169054.

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Shimizu H, Julius MA, Giarré M, Zheng Z, Brown AM, Kitajewski J. Transformation by Wnt family proteins correlates with regulation of beta-catenin. Cell Growth Differ. 1997 Dec;8(12):1349-58. PubMed PMID: 9419423.

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Bergstein I, Eisenberg LM, Bhalerao J, Jenkins NA, Copeland NG, Osborne MP, Bowcock AM, Brown AM. Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21. Genomics. 1997 Dec 15;46(3):450-8. doi: 10.1006/geno.1997.5041. PubMed PMID: 9441749.

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Giarré M, Semënov MV, Brown AM. Wnt signaling stabilizes the dual-function protein beta-catenin in diverse cell types. Ann N Y Acad Sci. 1998 Oct 23;857:43-55. doi: 10.1111/j.1749-6632.1998.tb10106.x. PubMed PMID: 9917831.

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Edelmann W, Yang K, Kuraguchi M, Heyer J, Lia M, Kneitz B, Fan K, Brown AM, Lipkin M, Kucherlapati R. Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice. Cancer Res. 1999 Mar 15;59(6):1301-7. PubMed PMID: 10096563.

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Howe LR, Subbaramaiah K, Chung WJ, Dannenberg AJ, Brown AM. Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells. Cancer Res. 1999 Apr 1;59(7):1572-7. PubMed PMID: 10197631.

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Arias AM, Brown AM, Brennan K. Wnt signalling: pathway or network?. Curr Opin Genet Dev. 1999 Aug;9(4):447-54. doi: 10.1016/s0959-437x(99)80068-9. Review. PubMed PMID: 10449358.

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Ai Z, Fischer A, Spray DC, Brown AM, Fishman GI. Wnt-1 regulation of connexin43 in cardiac myocytes. J Clin Invest. 2000 Jan;105(2):161-71. doi: 10.1172/JCI7798. PubMed PMID: 10642594; PubMed Central PMCID: PMC377428.

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Borycki A, Brown AM, Emerson CP Jr. Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites. Development. 2000 May;127(10):2075-87. doi: 10.1242/dev.127.10.2075. PubMed PMID: 10769232.

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Bournat JC, Brown AM, Soler AP. Wnt-1 dependent activation of the survival factor NF-kappaB in PC12 cells. J Neurosci Res. 2000 Jul 1;61(1):21-32. doi: 10.1002/1097-4547(20000701)61:1<21::AID-JNR3>3.0.CO;2-7. PubMed PMID: 10861796.

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Galbiati F, Volonte D, Brown AM, Weinstein DE, Ben-Ze'ev A, Pestell RG, Lisanti MP. Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains. J Biol Chem. 2000 Jul 28;275(30):23368-77. doi: 10.1074/jbc.M002020200. PubMed PMID: 10816572.

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Kuraguchi M, Edelmann W, Yang K, Lipkin M, Kucherlapati R, Brown AM. Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency. Oncogene. 2000 Nov 23;19(50):5755-63. doi: 10.1038/sj.onc.1203962. PubMed PMID: 11126362.

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Howe LR, Subbaramaiah K, Brown AM, Dannenberg AJ. Cyclooxygenase-2: a target for the prevention and treatment of breast cancer. Endocr Relat Cancer. 2001 Jun;8(2):97-114. doi: 10.1677/erc.0.0080097. Review. PubMed PMID: 11397667.

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Howe LR, Crawford HC, Subbaramaiah K, Hassell JA, Dannenberg AJ, Brown AM. PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2. J Biol Chem. 2001 Jun 8;276(23):20108-15. doi: 10.1074/jbc.M010692200. Epub 2001 Mar 26. PubMed PMID: 11274170.

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Brown AM. Wnt signaling in breast cancer: have we come full circle?. Breast Cancer Res. 2001;3(6):351-5. doi: 10.1186/bcr321. Epub 2001 Sep 6. Review. PubMed PMID: 11737884; PubMed Central PMCID: PMC138699.

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Kuraguchi M, Yang K, Wong E, Avdievich E, Fan K, Kolodner RD, Lipkin M, Brown AM, Kucherlapati R, Edelmann W. The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. Cancer Res. 2001 Nov 1;61(21):7934-42. PubMed PMID: 11691815.

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You Z, Saims D, Chen S, Zhang Z, Guttridge DC, Guan KL, MacDougald OA, Brown AM, Evan G, Kitajewski J, Wang CY. Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis. J Cell Biol. 2002 Apr 29;157(3):429-40. doi: 10.1083/jcb.200201110. Epub 2002 Apr 29. PubMed PMID: 11980918; PubMed Central PMCID: PMC2173296.

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Howe LR, Subbaramaiah K, Patel J, Masferrer JL, Deora A, Hudis C, Thaler HT, Muller WJ, Du B, Brown AM, Dannenberg AJ. Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer. Cancer Res. 2002 Oct 1;62(19):5405-7. PubMed PMID: 12359744.

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Wong E, Yang K, Kuraguchi M, Werling U, Avdievich E, Fan K, Fazzari M, Jin B, Brown AM, Lipkin M, Edelmann W. Mbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14937-42. doi: 10.1073/pnas.232579299. Epub 2002 Nov 4. PubMed PMID: 12417741; PubMed Central PMCID: PMC137523.

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Brennan K, Brown AM. Is there a role for Notch signalling in human breast cancer?. Breast Cancer Res. 2003;5(2):69-75. doi: 10.1186/bcr559. Epub 2003 Jan 20. Review. PubMed PMID: 12631384; PubMed Central PMCID: PMC154142.

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Howe LR, Watanabe O, Leonard J, Brown AM. Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation. Cancer Res. 2003 Apr 15;63(8):1906-13. PubMed PMID: 12702582.