My Bibliography

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Kim AI, Pasiukova EG, Karpova NN, Razorenova OV. [Genomic factors regulating the transposition of drosophila mobile elements]. Genetika. 1999 Nov;35(11):1511-21. Review. PubMed PMID: 10624574.

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Kusulidu LK, Karpova NN, Razorenova OV, Glukhov IA, Kim AI, Lyubomirskaya NV, Ilyin YV. Structural polymorphism of the transposable element MDG4 (gypsy) in Drosophila melanogaster strains. Doklady Akademii nauk. 2001; 376(1):133-138.

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Razorenova OV, Karpova NN, Smirnova IuB, Kusulidu LK, Reneva NK, Subocheva EA, Kim AI, Liubomirskaia NV, Il'in IuV. [Interlineage distribution and characteristics of the structure of two subfamilies of Drosophila melanogaster MDG4 (gypsy) retrotransposon]. Genetika. 2001 Feb;37(2):175-82. PubMed PMID: 11253423.

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Lyubomirskaya NV, Smirnova JB, Razorenova OV, Karpova NN, Surkov SA, Avedisov SN, Kim AI, Ilyin YV. Two variants of the Drosophila melanogaster retrotransposon gypsy (mdg4): structural and functional differences, and distribution in fly stocks. Mol Genet Genomics. 2001 Apr;265(2):367-74. doi: 10.1007/s004380000427. PubMed PMID: 11361349.

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Kusulidu LK, Karpova NN, Razorenova OV, Glukhov IA, Kim AI, Liubomirskaia NV, Il'in IuV. [Mobile genetic element MDG4 (gypsy) in Drosophila melanogaster. Features of structure and regulation of transposition]. Genetika. 2001 Dec;37(12):1589-97. PubMed PMID: 11785284.

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Gurova KV, Hill JE, Razorenova OV, Chumakov PM, Gudkov AV. p53 pathway in renal cell carcinoma is repressed by a dominant mechanism. Cancer Res. 2004 Mar 15;64(6):1951-8. doi: 10.1158/0008-5472.can-03-1541. PubMed PMID: 15026329.

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Razorenova OV, Agapova LS, Chumakov PM. p53 gene expression and activation of p53-dependent transcription in melanoma cell lines. Mol Biol (Mosk). 2005; 39(3):445-456.

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Razorenova OV, Agapova LS, Budanov AV, Ivanov AV, Strunina SM, Chumakov PM. [Retroviral reporter systems for the assessment of activity of stress-induced signal transduction pathways controlled by p53, HIF-1 and HSF-1 transcription factors]. Mol Biol (Mosk). 2005 Mar-Apr;39(2):286-93. PubMed PMID: 15856952; PubMed Central PMCID: PMC2774898.

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Razorenova OV, Ivanov AV, Budanov AV, Chumakov PM. Virus-based reporter systems for monitoring transcriptional activity of hypoxia-inducible factor 1. Gene. 2005 Apr 25;350(1):89-98. doi: 10.1016/j.gene.2005.02.006. PubMed PMID: 15794924; PubMed Central PMCID: PMC2773277.

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De S, Razorenova O, McCabe NP, O'Toole T, Qin J, Byzova TV. VEGF-integrin interplay controls tumor growth and vascularization. Proc Natl Acad Sci U S A. 2005 May 24;102(21):7589-94. doi: 10.1073/pnas.0502935102. Epub 2005 May 16. PubMed PMID: 15897451; PubMed Central PMCID: PMC1129024.

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Narizhneva NV, Razorenova OV, Podrez EA, Chen J, Chandrasekharan UM, DiCorleto PE, Plow EF, Topol EJ, Byzova TV. Thrombospondin-1 up-regulates expression of cell adhesion molecules and promotes monocyte binding to endothelium. FASEB J. 2005 Jul;19(9):1158-60. doi: 10.1096/fj.04-3310fje. Epub 2005 Apr 15. PubMed PMID: 15833768; PubMed Central PMCID: PMC1569946.

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Chen J, Somanath PR, Razorenova O, Chen WS, Hay N, Bornstein P, Byzova TV. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo. Nat Med. 2005 Nov;11(11):1188-96. doi: 10.1038/nm1307. Epub 2005 Oct 16. PubMed PMID: 16227992; PubMed Central PMCID: PMC2277080.

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Boiko AD, Porteous S, Razorenova OV, Krivokrysenko VI, Williams BR, Gudkov AV. A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation. Genes Dev. 2006 Jan 15;20(2):236-52. doi: 10.1101/gad.1372606. PubMed PMID: 16418486; PubMed Central PMCID: PMC1356114.

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Somanath PR, Razorenova OV, Chen J, Byzova TV. Akt1 in endothelial cell and angiogenesis. Cell Cycle. 2006 Mar;5(5):512-8. doi: 10.4161/cc.5.5.2538. Epub 2006 Mar 1. Review. PubMed PMID: 16552185; PubMed Central PMCID: PMC1569947.

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Mahabeleshwar GH, Chen J, Feng W, Somanath PR, Razorenova OV, Byzova TV. Integrin affinity modulation in angiogenesis. Cell Cycle. 2008 Feb 1;7(3):335-47. doi: 10.4161/cc.7.3.5234. Epub 2007 Nov 1. PubMed PMID: 18287811; PubMed Central PMCID: PMC2677212.

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Malinin NL, Zhang L, Choi J, Ciocea A, Razorenova O, Ma YQ, Podrez EA, Tosi M, Lennon DP, Caplan AI, Shurin SB, Plow EF, Byzova TV. A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans. Nat Med. 2009 Mar;15(3):313-8. doi: 10.1038/nm.1917. Epub 2009 Feb 22. PubMed PMID: 19234460; PubMed Central PMCID: PMC2857384.

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Krieg AJ, Rankin EB, Chan D, Razorenova O, Fernandez S, Giaccia AJ. Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth. Mol Cell Biol. 2010 Jan;30(1):344-53. doi: 10.1128/MCB.00444-09. PubMed PMID: 19858293; PubMed Central PMCID: PMC2798291.

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Razorenova OV, Giaccia AJ. Hypoxia, Gene Expression, and Metastasis. In: Bagley RG, editor. The Tumor Microenvironment New York: Springer; 2010. Chapter 3. 43-58p.

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Boiko AD, Razorenova OV, van de Rijn M, Swetter SM, Johnson DL, Ly DP, Butler PD, Yang GP, Joshua B, Kaplan MJ, Longaker MT, Weissman IL. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature. 2010 Jul 1;466(7302):133-7. doi: 10.1038/nature09161. PubMed PMID: 20596026; PubMed Central PMCID: PMC2898751.

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Chernikova SB, Dorth JA, Razorenova OV, Game JC, Brown JM. Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells. Radiat Res. 2010 Nov;174(5):558-65. doi: 10.1667/RR2184.1. Epub 2010 Aug 25. PubMed PMID: 20738173; PubMed Central PMCID: PMC2988074.

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Razorenova OV, Finger EC, Colavitti R, Chernikova SB, Boiko AD, Chan CK, Krieg A, Bedogni B, LaGory E, Weissman IL, Broome-Powell M, Giaccia AJ. VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1931-6. doi: 10.1073/pnas.1011777108. Epub 2011 Jan 13. PubMed PMID: 21233420; PubMed Central PMCID: PMC3033256.

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Razorenova OV. Brain and muscle ARNT-like protein BMAL1 regulates ROS homeostasis and senescence: a possible link to hypoxia-inducible factor-mediated pathway. Cell Cycle. 2012 Jan 15;11(2):213-4. doi: 10.4161/cc.11.2.18786. Epub 2012 Jan 15. PubMed PMID: 22223094.

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Chernikova SB, Razorenova OV, Higgins JP, Sishc BJ, Nicolau M, Dorth JA, Chernikova DA, Kwok S, Brooks JD, Bailey SM, Game JC, Brown JM. Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability. Cancer Res. 2012 Apr 15;72(8):2111-9. doi: 10.1158/0008-5472.CAN-11-2209. Epub 2012 Feb 21. PubMed PMID: 22354749; PubMed Central PMCID: PMC3328627.

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Razorenova OV, Castellini L, Colavitti R, Edgington LE, Nicolau M, Huang X, Bedogni B, Mills EM, Bogyo M, Giaccia AJ. The apoptosis repressor with a CARD domain (ARC) gene is a direct hypoxia-inducible factor 1 target gene and promotes survival and proliferation of VHL-deficient renal cancer cells. Mol Cell Biol. 2014 Feb;34(4):739-51. doi: 10.1128/MCB.00644-12. Epub 2013 Dec 16. PubMed PMID: 24344197; PubMed Central PMCID: PMC3911479.

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Thompson JM, Nguyen QH, Singh M, Razorenova OV. Approaches to identifying synthetic lethal interactions in cancer. Yale J Biol Med. 2015 Jun;88(2):145-55. eCollection 2015 Jun. Review. PubMed PMID: 26029013; PubMed Central PMCID: PMC4445436.

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Hou J, Wright HJ, Chan N, Tran R, Razorenova OV, Potma EO, Tromberg BJ. Correlating two-photon excited fluorescence imaging of breast cancer cellular redox state with seahorse flux analysis of normalized cellular oxygen consumption. J Biomed Opt. 2016 Jun 1;21(6):60503. doi: 10.1117/1.JBO.21.6.060503. PubMed PMID: 27300321; PubMed Central PMCID: PMC4906146.

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Wright HJ, Arulmoli J, Motazedi M, Nelson LJ, Heinemann FS, Flanagan LA, Razorenova OV. CDCP1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer. Oncogene. 2016 Sep 8;35(36):4762-72. doi: 10.1038/onc.2016.7. Epub 2016 Feb 15. PubMed PMID: 26876198; PubMed Central PMCID: PMC4985505.

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Wright HJ, Police AM, Razorenova OV. Targeting CDCP1 dimerization in triple-negative breast cancer. Cell Cycle. 2016 Sep 16;15(18):2385-6. doi: 10.1080/15384101.2016.1204849. Epub 2016 Jun 30. PubMed PMID: 27362899; PubMed Central PMCID: PMC5026807.

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Arulmoli J, Wright HJ, Phan DTT, Sheth U, Que RA, Botten GA, Keating M, Botvinick EL, Pathak MM, Zarembinski TI, Yanni DS, Razorenova OV, Hughes CCW, Flanagan LA. Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering. Acta Biomater. 2016 Oct 1;43:122-138. doi: 10.1016/j.actbio.2016.07.043. Epub 2016 Jul 27. PubMed PMID: 27475528; PubMed Central PMCID: PMC5386322.

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Thompson JM, Nguyen QH, Singh M, Pavesic MW, Nesterenko I, Nelson LJ, Liao AC, Razorenova OV. Rho-associated kinase 1 inhibition is synthetically lethal with von Hippel-Lindau deficiency in clear cell renal cell carcinoma. Oncogene. 2017 Feb 23;36(8):1080-1089. doi: 10.1038/onc.2016.272. Epub 2016 Nov 14. PubMed PMID: 27841867; PubMed Central PMCID: PMC5323317.

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Castellini L, Moon EJ, Razorenova OV, Krieg AJ, von Eyben R, Giaccia AJ. KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage. Nucleic Acids Res. 2017 Apr 20;45(7):3674-3692. doi: 10.1093/nar/gkw1281. PubMed PMID: 28073943; PubMed Central PMCID: PMC5397198.

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Wright HJ, Hou J, Xu B, Cortez M, Potma EO, Tromberg BJ, Razorenova OV. CDCP1 drives triple-negative breast cancer metastasis through reduction of lipid-droplet abundance and stimulation of fatty acid oxidation. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6556-E6565. doi: 10.1073/pnas.1703791114. Epub 2017 Jul 24. PubMed PMID: 28739932; PubMed Central PMCID: PMC5559020.

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Thompson JM, Alvarez A, Singha MK, Pavesic MW, Nguyen QH, Nelson LJ, Fruman DA, Razorenova OV. Targeting the Mevalonate Pathway Suppresses VHL-Deficient CC-RCC through an HIF-Dependent Mechanism. Mol Cancer Ther. 2018 Aug;17(8):1781-1792. doi: 10.1158/1535-7163.MCT-17-1076. Epub 2018 May 2. PubMed PMID: 29720560; PubMed Central PMCID: PMC6072609.

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Thompson JM, Landman J, Razorenova OV. Targeting the RhoGTPase/ROCK pathway for the treatment of VHL/HIF pathway-driven cancers. Small GTPases. 2020 Jan;11(1):32-38. doi: 10.1080/21541248.2017.1336193. Epub 2017 Jul 7. Review. PubMed PMID: 28632992; PubMed Central PMCID: PMC6959287.

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Vargas RE, Duong VT, Han H, Ta AP, Chen Y, Zhao S, Yang B, Seo G, Chuc K, Oh S, El Ali A, Razorenova OV, Chen J, Luo R, Li X, Wang W. Elucidation of WW domain ligand binding specificities in the Hippo pathway reveals STXBP4 as YAP inhibitor. EMBO J. 2020 Jan 2;39(1):e102406. doi: 10.15252/embj.2019102406. Epub 2019 Nov 29. PubMed PMID: 31782549; PubMed Central PMCID: PMC6939200.

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Nelson LJ, Wright HJ, Dinh NB, Nguyen KD, Razorenova OV, Heinemann FS. Src Kinase Is Biphosphorylated at Y416/Y527 and Activates the CUB-Domain Containing Protein 1/Protein Kinase C δ Pathway in a Subset of Triple-Negative Breast Cancers. Am J Pathol. 2020 Feb;190(2):484-502. doi: 10.1016/j.ajpath.2019.10.017. Epub 2019 Dec 13. PubMed PMID: 31843498; PubMed Central PMCID: PMC6983918.

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Joshi K, Javani A, Park J, Velasco V, Xu B, Razorenova O, Esfandyarpour R. A Machine Learning-Assisted Nanoparticle-Printed Biochip for Real-Time Single Cancer Cell Analysis. Adv Biosyst. 2020 Nov;4(11):e2000160. doi: 10.1002/adbi.202000160. Epub 2020 Oct 7. PubMed PMID: 33025770.

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Pollan SG, Teng PC, Jan YJ, Livingstone J, Huang C, Kim M, Mariscal J, Rodriguez M, Chen JF, You S, DiVizio D, Boutros PC, Chan KS, Rasorenova O, Cress A, Spassov D, Moasser M, Posadas EM, Freedland SJ, Freeman MR, Zheng JJ, Knudsen BS. Loss of CDCP1 triggers FAK activation in detached prostate cancer cells. Am J Clin Exp Urol. 2021;9(4):350-366. eCollection 2021. PubMed PMID: 34541033; PubMed Central PMCID: PMC8446766.

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Nelson LJ, Castro KE, Xu B, Li J, Dinh NB, Thompson JM, Woytash J, Kipp KR, Razorenova OV. Synthetic lethality of cyclin-dependent kinase inhibitor Dinaciclib with VHL-deficiency allows for selective targeting of clear cell renal cell carcinoma. Cell Cycle. 2022 May;21(10):1103-1119. doi: 10.1080/15384101.2022.2041783. Epub 2022 Mar 4. PubMed PMID: 35240916; PubMed Central PMCID: PMC9037521.