My Bibliography

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Gouze JN, Stoddart MJ, Gouze E, Palmer GD, Ghivizzani SC, Grodzinsky AJ, Evans CH. In vitro gene transfer to chondrocytes and synovial fibroblasts by adenoviral vectors. Methods Mol Med. 2004;100:147-64. doi: 10.1385/1-59259-810-2:147. PubMed PMID: 15280594.

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Stoddart MJ, Ettinger L, Häuselmann HJ. Generation of a scaffold free cartilage-like implant from a small amount of starting material. J Cell Mol Med. 2006 Apr-Jun;10(2):480-92. doi: 10.1111/j.1582-4934.2006.tb00413.x. PubMed PMID: 16796813; PubMed Central PMCID: PMC3933135.

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Davies CM, Jones DB, Stoddart MJ, Koller K, Smith E, Archer CW, Richards RG. Mechanically loaded ex vivo bone culture system 'Zetos': systems and culture preparation. Eur Cell Mater. 2006 Apr 12;11:57-75; discussion 75. doi: 10.22203/ecm.v011a07. PubMed PMID: 16612792.

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Stoddart MJ, Furlong PI, Simpson A, Davies CM, Richards RG. A comparison of non-radioactive methods for assessing viability in ex vivo cultured cancellous bone: technical note. Eur Cell Mater. 2006 Aug 3;12:16-25; discussion 16-25. doi: 10.22203/ecm.v012a02. PubMed PMID: 16888702.

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Jubel A, Fischer J, Andermahr J, Isenberg J, Schiffer G, Stoddart M, Rehm KE, Häuselmann HJ. [Implantation of matrix-free cartilage transplants in standardized defects in sheep knee joints]. Orthopade. 2006 Dec;35(12):1246-57. doi: 10.1007/s00132-006-1021-z. PubMed PMID: 17111166.

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Stoddart MJ, Ettinger L, Häuselmann HJ. Enhanced matrix synthesis in de novo, scaffold free cartilage-like tissue subjected to compression and shear. Biotechnol Bioeng. 2006 Dec 20;95(6):1043-51. doi: 10.1002/bit.21052. PubMed PMID: 16804949.

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Richards RG, Simpson AE, Jaehn K, Furlong PI, Stoddart MJ. Establishing a 3D ex vivo culture system for investigations of bone metabolism and biomaterial interactions. ALTEX. 2007;24 Spec No:56-9. PubMed PMID: 19835059.

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Halloran DO, Grad S, Stoddart M, Dockery P, Alini M, Pandit AS. An injectable cross-linked scaffold for nucleus pulposus regeneration. Biomaterials. 2008 Feb;29(4):438-47. doi: 10.1016/j.biomaterials.2007.10.009. Epub 2007 Oct 23. PubMed PMID: 17959242.

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Palmer GD, Stoddart MJ, Gouze E, Gouze JN, Ghivizzani SC, Porter RM, Evans CH. A simple, lanthanide-based method to enhance the transduction efficiency of adenovirus vectors. Gene Ther. 2008 Mar;15(5):357-63. doi: 10.1038/sj.gt.3303092. Epub 2008 Jan 24. PubMed PMID: 18283289.

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Jubel A, Andermahr J, Schiffer G, Fischer J, Rehm KE, Stoddart MJ, Häuselmann HJ. Transplantation of de novo scaffold-free cartilage implants into sheep knee chondral defects. Am J Sports Med. 2008 Aug;36(8):1555-64. doi: 10.1177/0363546508321474. PubMed PMID: 18658022.

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Simpson AE, Stoddart MJ, Davies CM, Jähn K, Furlong PI, Gasser JA, Jones DB, Noble BS, Richards RG. TGFbeta3 and loading increases osteocyte survival in human cancellous bone cultured ex vivo. Cell Biochem Funct. 2009 Jan;27(1):23-9. doi: 10.1002/cbf.1529. PubMed PMID: 19107876.

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Stoddart MJ, Grad S, Eglin D, Alini M. Cells and biomaterials in cartilage tissue engineering. Regen Med. 2009 Jan;4(1):81-98. doi: 10.2217/17460751.4.1.81. Review. PubMed PMID: 19105618.

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Li Z, Kupcsik L, Yao SJ, Alini M, Stoddart MJ. Chondrogenesis of human bone marrow mesenchymal stem cells in fibrin-polyurethane composites. Tissue Eng Part A. 2009 Jul;15(7):1729-37. doi: 10.1089/ten.tea.2008.0247. PubMed PMID: 19115827.

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Kupcsik L, Alini M, Stoddart MJ. Epsilon-aminocaproic acid is a useful fibrin degradation inhibitor for cartilage tissue engineering. Tissue Eng Part A. 2009 Aug;15(8):2309-13. doi: 10.1089/ten.tea.2008.0400. PubMed PMID: 19086806.

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Salzmann GM, Nuernberger B, Schmitz P, Anton M, Stoddart MJ, Grad S, Milz S, Tischer T, Vogt S, Gansbacher B, Imhoff AB, Alini M. Physicobiochemical synergism through gene therapy and functional tissue engineering for in vitro chondrogenesis. Tissue Eng Part A. 2009 Sep;15(9):2513-24. doi: 10.1089/ten.tea.2008.0479. PubMed PMID: 19292668.

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Klaue K, Knothe U, Anton C, Pfluger DH, Stoddart M, Masquelet AC, Perren SM. Bone regeneration in long-bone defects: tissue compartmentalisation? In vivo study on bone defects in sheep. Injury. 2009 Nov;40 Suppl 4:S95-102. doi: 10.1016/j.injury.2009.10.043. PubMed PMID: 19895960.

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Kupcsik L, Meurya T, Flury M, Stoddart M, Alini M. Statin-induced calcification in human mesenchymal stem cells is cell death related. J Cell Mol Med. 2009 Nov-Dec;13(11-12):4465-73. doi: 10.1111/j.1582-4934.2008.00545.x. PubMed PMID: 19602044; PubMed Central PMCID: PMC4515062.

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Li Z, Yao SJ, Alini M, Stoddart MJ. Chondrogenesis of human bone marrow mesenchymal stem cells in fibrin-polyurethane composites is modulated by frequency and amplitude of dynamic compression and shear stress. Tissue Eng Part A. 2010 Feb;16(2):575-84. doi: 10.1089/ten.TEA.2009.0262. PubMed PMID: 19737049.

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Jähn K, Braunstein V, Furlong PI, Simpson AE, Richards RG, Stoddart MJ. A rapid method for the generation of uniform acellular bone explants: a technical note. J Orthop Surg Res. 2010 May 10;5:32. doi: 10.1186/1749-799X-5-32. PubMed PMID: 20459728; PubMed Central PMCID: PMC2873550.

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Kupcsik L, Stoddart MJ, Li Z, Benneker LM, Alini M. Improving chondrogenesis: potential and limitations of SOX9 gene transfer and mechanical stimulation for cartilage tissue engineering. Tissue Eng Part A. 2010 Jun;16(6):1845-55. doi: 10.1089/ten.TEA.2009.0531. PubMed PMID: 20067399.

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Li Z, Kupcsik L, Yao SJ, Alini M, Stoddart MJ. Mechanical load modulates chondrogenesis of human mesenchymal stem cells through the TGF-beta pathway. J Cell Mol Med. 2010 Jun;14(6A):1338-46. doi: 10.1111/j.1582-4934.2009.00780.x. Epub 2009 May 11. PubMed PMID: 19432813; PubMed Central PMCID: PMC3828850.

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Jähn K, Richards RG, Archer CW, Stoddart MJ. Pellet culture model for human primary osteoblasts. Eur Cell Mater. 2010 Sep 6;20:149-61. doi: 10.22203/ecm.v020a13. PubMed PMID: 20818597.

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Jähn K, Stoddart MJ. Viability assessment of osteocytes using histological lactate dehydrogenase activity staining on human cancellous bone sections. Methods Mol Biol. 2011;740:141-8. doi: 10.1007/978-1-61779-108-6_15. PubMed PMID: 21468975.

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Stoddart MJ. Cell viability assays: introduction. Methods Mol Biol. 2011;740:1-6. doi: 10.1007/978-1-61779-108-6_1. Review. PubMed PMID: 21468961.

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Stoddart MJ. WST-8 analysis of cell viability during osteogenesis of human mesenchymal stem cells. Methods Mol Biol. 2011;740:21-5. doi: 10.1007/978-1-61779-108-6_4. PubMed PMID: 21468964.

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Salzmann GM, Buchberger MS, Stoddart MJ, Grad S, Milz S, Niemyer P, Sudkamp NP, Imhoff AB, Alini M. Varying regional topology within knee articular chondrocytes under simulated in vivo conditions. Tissue Eng Part A. 2011 Feb;17(3-4):451-61. doi: 10.1089/ten.TEA.2009.0819. Epub 2010 Oct 12. PubMed PMID: 20807006.

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Li Z, Yao SJ, Alini M, Stoddart MJ. The role of retinoic acid receptor inhibitor LE135 on the osteochondral differentiation of human bone marrow mesenchymal stem cells. J Cell Biochem. 2011 Mar;112(3):963-70. doi: 10.1002/jcb.23013. PubMed PMID: 21308729.

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Grad S, Eglin D, Alini M, Stoddart MJ. Physical stimulation of chondrogenic cells in vitro: a review. Clin Orthop Relat Res. 2011 Oct;469(10):2764-72. doi: 10.1007/s11999-011-1819-9. Review. PubMed PMID: 21344272; PubMed Central PMCID: PMC3171534.

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Schätti O, Grad S, Goldhahn J, Salzmann G, Li Z, Alini M, Stoddart MJ. A combination of shear and dynamic compression leads to mechanically induced chondrogenesis of human mesenchymal stem cells. Eur Cell Mater. 2011 Oct 11;22:214-25. doi: 10.22203/ecm.v022a17. PubMed PMID: 22048899.

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Czekanska EM, Stoddart MJ, Richards RG, Hayes JS. In search of an osteoblast cell model for in vitro research. Eur Cell Mater. 2012 Jul 9;24:1-17. doi: 10.22203/ecm.v024a01. Review. PubMed PMID: 22777949.

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Illien-Jünger S, Pattappa G, Peroglio M, Benneker LM, Stoddart MJ, Sakai D, Mochida J, Grad S, Alini M. Homing of mesenchymal stem cells in induced degenerative intervertebral discs in a whole organ culture system. Spine (Phila Pa 1976). 2012 Oct 15;37(22):1865-73. doi: 10.1097/BRS.0b013e3182544a8a. PubMed PMID: 22433498.

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Stoddart MJ, Richards RG, Alini M. In vitro experiments with primary mammalian cells: to pool or not to pool?. Eur Cell Mater. 2012 Nov 9;24:i-ii. doi: 10.22203/ecm.v024a00. PubMed PMID: 23143921.

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Gardner OF, Archer CW, Alini M, Stoddart MJ. Chondrogenesis of mesenchymal stem cells for cartilage tissue engineering. Histol Histopathol. 2013 Jan;28(1):23-42. doi: 10.14670/HH-28.23. Review. PubMed PMID: 23233057.

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Neumann AJ, Schroeder J, Alini M, Archer CW, Stoddart MJ. Enhanced adenovirus transduction of hMSCs using 3D hydrogel cell carriers. Mol Biotechnol. 2013 Feb;53(2):207-16. doi: 10.1007/s12033-012-9522-y. PubMed PMID: 22382454.

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Petrou M, Niemeyer P, Stoddart MJ, Grad S, Bernstein A, Mayr HO, Bode G, Sudkamp N, Alini M, Salzmann GM. Mesenchymal stem cell chondrogenesis: composite growth factor-bioreactor synergism for human stem cell chondrogenesis. Regen Med. 2013 Mar;8(2):157-70. doi: 10.2217/rme.13.3. PubMed PMID: 23477396.

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Beck A, Nehrbass D, Stoddart MJ, Schiuma D, Green J, Lansdowne JL, Richards RG, Bouré LP. The use of Reamer Irrigator Aspirator (RIA) autograft harvest in the treatment of critical-sized iliac wing defects in sheep: investigation of dexamethasone and beta-tricalcium phosphate augmentation. Bone. 2013 Apr;53(2):554-65. doi: 10.1016/j.bone.2012.12.017. Epub 2012 Dec 27. PubMed PMID: 23274345.

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Wang N, Grad S, Stoddart MJ, Niemeyer P, Südkamp NP, Pestka J, Alini M, Chen J, Salzmann GM. Bioreactor-Induced Chondrocyte Maturation Is Dependent on Cell Passage and Onset of Loading. Cartilage. 2013 Apr;4(2):165-76. doi: 10.1177/1947603512471345. PubMed PMID: 26069659; PubMed Central PMCID: PMC4297099.

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Johnstone B, Alini M, Cucchiarini M, Dodge GR, Eglin D, Guilak F, Madry H, Mata A, Mauck RL, Semino CE, Stoddart MJ. Tissue engineering for articular cartilage repair--the state of the art. Eur Cell Mater. 2013 May 2;25:248-67. doi: 10.22203/ecm.v025a18. Review. PubMed PMID: 23636950.

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Neumann AJ, Alini M, Archer CW, Stoddart MJ. Chondrogenesis of human bone marrow-derived mesenchymal stem cells is modulated by complex mechanical stimulation and adenoviral-mediated overexpression of bone morphogenetic protein 2. Tissue Eng Part A. 2013 Jun;19(11-12):1285-94. doi: 10.1089/ten.TEA.2012.0411. Epub 2013 Feb 19. PubMed PMID: 23289669.

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Bruderer M, Alini M, Stoddart MJ. Role of HOXA9 and VEZF1 in endothelial biology. J Vasc Res. 2013;50(4):265-78. doi: 10.1159/000353287. Epub 2013 Jul 5. Review. PubMed PMID: 23921720.

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Randau TM, Schildberg FA, Alini M, Wimmer MD, Haddouti el-M, Gravius S, Ito K, Stoddart MJ. The effect of dexamethasone and triiodothyronine on terminal differentiation of primary bovine chondrocytes and chondrogenically differentiated mesenchymal stem cells. PLoS One. 2013;8(8):e72973. doi: 10.1371/journal.pone.0072973. eCollection 2013. PubMed PMID: 23977373; PubMed Central PMCID: PMC3745539.

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Hilz FM, Ahrens P, Grad S, Stoddart MJ, Dahmani C, Wilken FL, Sauerschnig M, Niemeyer P, Zwingmann J, Burgkart R, von Eisenhart-Rothe R, Südkamp NP, Weyh T, Imhoff AB, Alini M, Salzmann GM. Influence of extremely low frequency, low energy electromagnetic fields and combined mechanical stimulation on chondrocytes in 3-D constructs for cartilage tissue engineering. Bioelectromagnetics. 2014 Feb;35(2):116-28. doi: 10.1002/bem.21822. Epub 2013 Nov 6. PubMed PMID: 24203577.

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Zahedmanesh H, Stoddart M, Lezuo P, Forkmann C, Wimmmer MA, Alini M, Van Oosterwyck H. Deciphering mechanical regulation of chondrogenesis in fibrin-polyurethane composite scaffolds enriched with human mesenchymal stem cells: a dual computational and experimental approach. Tissue Eng Part A. 2014 Apr;20(7-8):1197-212. doi: 10.1089/ten.TEA.2013.0145. Epub 2014 Jan 11. PubMed PMID: 24199606; PubMed Central PMCID: PMC3993020.

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Wang N, Grad S, Stoddart MJ, Niemeyer P, Reising K, Schmal H, Südkamp NP, Alini M, Salzmann GM. Particulate cartilage under bioreactor-induced compression and shear. Int Orthop. 2014 May;38(5):1105-11. doi: 10.1007/s00264-013-2194-9. Epub 2013 Nov 28. PubMed PMID: 24287980; PubMed Central PMCID: PMC3997764.

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Torcasio A, Jähn K, Van Guyse M, Spaepen P, Tami AE, Vander Sloten J, Stoddart MJ, van Lenthe GH. Trabecular bone adaptation to low-magnitude high-frequency loading in microgravity. PLoS One. 2014;9(5):e93527. doi: 10.1371/journal.pone.0093527. eCollection 2014. PubMed PMID: 24787094; PubMed Central PMCID: PMC4008366.

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Madry H, Alini M, Stoddart MJ, Evans C, Miclau T, Steiner S. Barriers and strategies for the clinical translation of advanced orthopaedic tissue engineering protocols. Eur Cell Mater. 2014 May 6;27:17-21; discussion 21. doi: 10.22203/ecm.v027sa04. PubMed PMID: 24802613.

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Cucchiarini M, Madry H, Guilak F, Saris DB, Stoddart MJ, Koon Wong M, Roughley P. A vision on the future of articular cartilage repair. Eur Cell Mater. 2014 May 6;27:12-6. doi: 10.22203/ecm.v027sa03. PubMed PMID: 24802612.

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Bara JJ, Richards RG, Alini M, Stoddart MJ. Concise review: Bone marrow-derived mesenchymal stem cells change phenotype following in vitro culture: implications for basic research and the clinic. Stem Cells. 2014 Jul;32(7):1713-23. doi: 10.1002/stem.1649. Review. PubMed PMID: 24449458.

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Czekanska EM, Stoddart MJ, Ralphs JR, Richards RG, Hayes JS. A phenotypic comparison of osteoblast cell lines versus human primary osteoblasts for biomaterials testing. J Biomed Mater Res A. 2014 Aug;102(8):2636-43. doi: 10.1002/jbm.a.34937. Epub 2013 Sep 6. PubMed PMID: 23983015.

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Bruderer M, Richards RG, Alini M, Stoddart MJ. Role and regulation of RUNX2 in osteogenesis. Eur Cell Mater. 2014 Oct 23;28:269-86. doi: 10.22203/ecm.v028a19. Review. PubMed PMID: 25340806.