My Bibliography

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Wang YZ, Fan H, Ji Y, Reynolds K, Gu R, Gan Q, Yamagami T, Zhao T, Hamad S, Bizen N, Takebayashi H, Chen Y, Wu S, Pleasure D, Lam K, Zhou CJ. Olig2 regulates terminal differentiation and maturation of peripheral olfactory sensory neurons. Cell Mol Life Sci. 2020 Sep;77(18):3597-3609. doi: 10.1007/s00018-019-03385-x. Epub 2019 Nov 22. PubMed PMID: 31758234; PubMed Central PMCID: PMC7242138.

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Pleasure D, Guo F, Chechneva O, Bannerman P, McDonough J, Burns T, Wang Y, Hull V. Pathophysiology and Treatment of Canavan Disease. Neurochem Res. 2020 Mar;45(3):561-565. doi: 10.1007/s11064-018-2693-6. Epub 2018 Dec 8. PubMed PMID: 30535831; PubMed Central PMCID: PMC11131954.

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Hull V, Wang Y, Burns T, Zhang S, Sternbach S, McDonough J, Guo F, Pleasure D. Antisense Oligonucleotide Reverses Leukodystrophy in Canavan Disease Mice. Ann Neurol. 2020 Mar;87(3):480-485. doi: 10.1002/ana.25674. Epub 2020 Jan 22. PubMed PMID: 31925837; PubMed Central PMCID: PMC8523037.

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Bannerman P, Guo F, Chechneva O, Burns T, Zhu X, Wang Y, Kim B, Singhal NK, McDonough JA, Pleasure D. Brain Nat8l Knockdown Suppresses Spongiform Leukodystrophy in an Aspartoacylase-Deficient Canavan Disease Mouse Model. Mol Ther. 2018 Mar 7;26(3):793-800. doi: 10.1016/j.ymthe.2018.01.002. Epub 2018 Jan 10. PubMed PMID: 29456021; PubMed Central PMCID: PMC5910673.

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Yamagami T, Pleasure DE, Lam KS, Zhou CJ. Transient activation of Wnt/β-catenin signaling reporter in fibrotic scar formation after compression spinal cord injury in adult mice. Biochem Biophys Res Commun. 2018 Feb 19;496(4):1302-1307. doi: 10.1016/j.bbrc.2018.02.004. Epub 2018 Feb 3. PubMed PMID: 29410176; PubMed Central PMCID: PMC5816694.

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Horiuchi M, Suzuki-Horiuchi Y, Akiyama T, Itoh A, Pleasure D, Carstens E, Itoh T. Differing intrinsic biological properties between forebrain and spinal oligodendroglial lineage cells. J Neurochem. 2017 Aug;142(3):378-391. doi: 10.1111/jnc.14074. Epub 2017 Jun 9. PubMed PMID: 28512742; PubMed Central PMCID: PMC6420720.

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Pleasure D. New hearts for Friedreich patients. J Neurol Sci. 2017 Apr 15;375:474-475. doi: 10.1016/j.jns.2017.01.035. Epub 2017 Jan 12. PubMed PMID: 28131391.

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Sohn J, Bannerman P, Guo F, Burns T, Miers L, Croteau C, Singhal NK, McDonough JA, Pleasure D. Suppressing N-Acetyl-l-Aspartate Synthesis Prevents Loss of Neurons in a Murine Model of Canavan Leukodystrophy. J Neurosci. 2017 Jan 11;37(2):413-421. doi: 10.1523/JNEUROSCI.2013-16.2016. PubMed PMID: 28077719; PubMed Central PMCID: PMC5242397.

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Singhal NK, Huang H, Li S, Clements R, Gadd J, Daniels A, Kooijman EE, Bannerman P, Burns T, Guo F, Pleasure D, Freeman E, Shriver L, McDonough J. The neuronal metabolite NAA regulates histone H3 methylation in oligodendrocytes and myelin lipid composition. Exp Brain Res. 2017 Jan;235(1):279-292. doi: 10.1007/s00221-016-4789-z. Epub 2016 Oct 5. PubMed PMID: 27709268; PubMed Central PMCID: PMC5875422.

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Bannerman P, Burns T, Xu J, Miers L, Pleasure D. Mice Hemizygous for a Pathogenic Mitofusin-2 Allele Exhibit Hind Limb/Foot Gait Deficits and Phenotypic Perturbations in Nerve and Muscle. PLoS One. 2016;11(12):e0167573. doi: 10.1371/journal.pone.0167573. eCollection 2016. PubMed PMID: 27907123; PubMed Central PMCID: PMC5132404.

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Pleasure D. Good Things Come in Threes: Genetically Engineered Neural Stem Cells Mitigate Chronic CNS Autoimmunity. Mol Ther. 2016 Aug;24(8):1338-9. doi: 10.1038/mt.2016.157. PubMed PMID: 27578282; PubMed Central PMCID: PMC5023387.

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Pleasure D. Precision Medicine for Charcot-Marie-Tooth Disease. JAMA Neurol. 2016 Jun 1;73(6):623-4. doi: 10.1001/jamaneurol.2016.0285. PubMed PMID: 27042938.

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Jiang P, Chen C, Liu XB, Pleasure DE, Liu Y, Deng W. Human iPSC-Derived Immature Astroglia Promote Oligodendrogenesis by Increasing TIMP-1 Secretion. Cell Rep. 2016 May 10;15(6):1303-15. doi: 10.1016/j.celrep.2016.04.011. Epub 2016 Apr 28. PubMed PMID: 27134175; PubMed Central PMCID: PMC4864503.

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Moreno MA, Burns T, Yao P, Miers L, Pleasure D, Soulika AM. Therapeutic depletion of monocyte-derived cells protects from long-term axonal loss in experimental autoimmune encephalomyelitis. J Neuroimmunol. 2016 Jan 15;290:36-46. doi: 10.1016/j.jneuroim.2015.11.004. Epub 2015 Nov 10. PubMed PMID: 26711567.

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Liu XB, Shen Y, Pleasure DE, Deng W. The vulnerability of thalamocortical circuitry to hypoxic-ischemic injury in a mouse model of periventricular leukomalacia. BMC Neurosci. 2016 Jan 5;17:2. doi: 10.1186/s12868-015-0237-4. PubMed PMID: 26733225; PubMed Central PMCID: PMC4702373.

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Guo F, Lang J, Sohn J, Hammond E, Chang M, Pleasure D. Canonical Wnt signaling in the oligodendroglial lineage--puzzles remain. Glia. 2015 Oct;63(10):1671-93. doi: 10.1002/glia.22813. Epub 2015 Mar 18. Review. PubMed PMID: 25782433.

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Chung SH, Biswas S, Selvaraj V, Liu XB, Sohn J, Jiang P, Chen C, Chmilewsky F, Marzban H, Horiuchi M, Pleasure DE, Deng W. The p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS. Cell Death Dis. 2015 May 7;6(5):e1748. doi: 10.1038/cddis.2015.119. PubMed PMID: 25950478; PubMed Central PMCID: PMC4669698.

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Guo F, Bannerman P, Mills Ko E, Miers L, Xu J, Burns T, Li S, Freeman E, McDonough JA, Pleasure D. Ablating N-acetylaspartate prevents leukodystrophy in a Canavan disease model. Ann Neurol. 2015 May;77(5):884-8. doi: 10.1002/ana.24392. Epub 2015 Mar 27. PubMed PMID: 25712859; PubMed Central PMCID: PMC11131957.

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Hammond E, Lang J, Maeda Y, Pleasure D, Angus-Hill M, Xu J, Horiuchi M, Deng W, Guo F. The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/β-catenin signaling. J Neurosci. 2015 Mar 25;35(12):5007-22. doi: 10.1523/JNEUROSCI.4787-14.2015. PubMed PMID: 25810530; PubMed Central PMCID: PMC6705374.

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Sohn J, Orosco L, Guo F, Chung SH, Bannerman P, Mills Ko E, Zarbalis K, Deng W, Pleasure D. The subventricular zone continues to generate corpus callosum and rostral migratory stream astroglia in normal adult mice. J Neurosci. 2015 Mar 4;35(9):3756-63. doi: 10.1523/JNEUROSCI.3454-14.2015. PubMed PMID: 25740506; PubMed Central PMCID: PMC6605576.

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Ekins S, Litterman NK, Arnold RJ, Burgess RW, Freundlich JS, Gray SJ, Higgins JJ, Langley B, Willis DE, Notterpek L, Pleasure D, Sereda MW, Moore A. A brief review of recent Charcot-Marie-Tooth research and priorities. F1000Res. 2015;4:53. doi: 10.12688/f1000research.6160.1. eCollection 2015. Review. PubMed PMID: 25901280; PubMed Central PMCID: PMC4392824.

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Itoh T, Pleasure D. The future of research in neuropathy. JAMA Neurol. 2015 Jan;72(1):5-7. doi: 10.1001/jamaneurol.2014.2346. Review. PubMed PMID: 25364864.

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Chetty S, Friedman AR, Taravosh-Lahn K, Kirby ED, Mirescu C, Guo F, Krupik D, Nicholas A, Geraghty A, Krishnamurthy A, Tsai MK, Covarrubias D, Wong A, Francis D, Sapolsky RM, Palmer TD, Pleasure D, Kaufer D. Stress and glucocorticoids promote oligodendrogenesis in the adult hippocampus. Mol Psychiatry. 2014 Dec;19(12):1275-1283. doi: 10.1038/mp.2013.190. Epub 2014 Feb 11. PubMed PMID: 24514565; PubMed Central PMCID: PMC4128957.

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Chechneva OV, Mayrhofer F, Daugherty DJ, Krishnamurty RG, Bannerman P, Pleasure DE, Deng W. A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury. Cell Death Dis. 2014 Oct 23;5(10):e1481. doi: 10.1038/cddis.2014.446. PubMed PMID: 25341035; PubMed Central PMCID: PMC4649529.

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Orosco LA, Ross AP, Cates SL, Scott SE, Wu D, Sohn J, Pleasure D, Pleasure SJ, Adamopoulos IE, Zarbalis KS. Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. Nat Commun. 2014 Sep 8;5:4692. doi: 10.1038/ncomms5692. PubMed PMID: 25198012; PubMed Central PMCID: PMC4159772.

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Itoh T, Horiuchi M, Ikeda RH Jr, Xu J, Bannerman P, Pleasure D, Penninger JM, Tournier C, Itoh A. ZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonates. J Neurosci. 2014 Aug 6;34(32):10729-42. doi: 10.1523/JNEUROSCI.0539-14.2014. PubMed PMID: 25100604; PubMed Central PMCID: PMC4200111.

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Lemmon VP, Ferguson AR, Popovich PG, Xu XM, Snow DM, Igarashi M, Beattie CE, Bixby JL. Minimum information about a spinal cord injury experiment: a proposed reporting standard for spinal cord injury experiments. J Neurotrauma. 2014 Aug 1;31(15):1354-61. doi: 10.1089/neu.2014.3400. Epub 2014 Jul 11. PubMed PMID: 24870067; PubMed Central PMCID: PMC4120647.

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Chen C, Jiang P, Xue H, Peterson SE, Tran HT, McCann AE, Parast MM, Li S, Pleasure DE, Laurent LC, Loring JF, Liu Y, Deng W. Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells. Nat Commun. 2014 Jul 18;5:4430. doi: 10.1038/ncomms5430. PubMed PMID: 25034944; PubMed Central PMCID: PMC4109022.

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Mills Ko E, Ma JH, Guo F, Miers L, Lee E, Bannerman P, Burns T, Ko D, Sohn J, Soulika AM, Pleasure D. Deletion of astroglial CXCL10 delays clinical onset but does not affect progressive axon loss in a murine autoimmune multiple sclerosis model. J Neuroinflammation. 2014 Jun 12;11:105. doi: 10.1186/1742-2094-11-105. PubMed PMID: 24924222; PubMed Central PMCID: PMC4066277.

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Moreno M, Bannerman P, Ma J, Guo F, Miers L, Soulika AM, Pleasure D. Conditional ablation of astroglial CCL2 suppresses CNS accumulation of M1 macrophages and preserves axons in mice with MOG peptide EAE. J Neurosci. 2014 Jun 11;34(24):8175-85. doi: 10.1523/JNEUROSCI.1137-14.2014. PubMed PMID: 24920622; PubMed Central PMCID: PMC4051973.

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Burns T, Miers L, Xu J, Man A, Moreno M, Pleasure D, Bannerman P. Neuronopathy in the motor neocortex in a chronic model of multiple sclerosis. J Neuropathol Exp Neurol. 2014 Apr;73(4):335-44. doi: 10.1097/NEN.0000000000000058. PubMed PMID: 24607968; PubMed Central PMCID: PMC4229074.

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Gan Q, Lee A, Suzuki R, Yamagami T, Stokes A, Nguyen BC, Pleasure D, Wang J, Chen HW, Zhou CJ. Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells. 2014 Jan;32(1):45-58. doi: 10.1002/stem.1561. PubMed PMID: 24115331; PubMed Central PMCID: PMC3963407.

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Zhao T, Gan Q, Stokes A, Lassiter RN, Wang Y, Chan J, Han JX, Pleasure DE, Epstein JA, Zhou CJ. β-catenin regulates Pax3 and Cdx2 for caudal neural tube closure and elongation. Development. 2014 Jan;141(1):148-57. doi: 10.1242/dev.101550. Epub 2013 Nov 27. PubMed PMID: 24284205; PubMed Central PMCID: PMC3865756.

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Jiang P, Chen C, Liu XB, Selvaraj V, Liu W, Feldman DH, Liu Y, Pleasure DE, Li RA, Deng W. Generation and characterization of spiking and nonspiking oligodendroglial progenitor cells from embryonic stem cells. Stem Cells. 2013 Dec;31(12):2620-31. doi: 10.1002/stem.1515. PubMed PMID: 23940003; PubMed Central PMCID: PMC3923867.

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Moreno M, Guo F, Mills Ko E, Bannerman P, Soulika A, Pleasure D. Origins and significance of astrogliosis in the multiple sclerosis model, MOG peptide EAE. J Neurol Sci. 2013 Oct 15;333(1-2):55-9. doi: 10.1016/j.jns.2012.12.014. Epub 2013 Jan 5. Review. PubMed PMID: 23294494; PubMed Central PMCID: PMC3624040.

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Patel PI, Pleasure D. Whither hope for pharmacological treatment of Charcot-Marie-Tooth disease type 1A?. JAMA Neurol. 2013 Aug;70(8):969-71. doi: 10.1001/jamaneurol.2013.3285. PubMed PMID: 23797977.

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Daugherty DJ, Selvaraj V, Chechneva OV, Liu XB, Pleasure DE, Deng W. A TSPO ligand is protective in a mouse model of multiple sclerosis. EMBO Mol Med. 2013 Jun;5(6):891-903. doi: 10.1002/emmm.201202124. Epub 2013 May 17. PubMed PMID: 23681668; PubMed Central PMCID: PMC3779450.

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Chung SH, Guo F, Jiang P, Pleasure DE, Deng W. Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. Cell Death Dis. 2013 Mar 14;4(3):e546. doi: 10.1038/cddis.2013.74. PubMed PMID: 23492777; PubMed Central PMCID: PMC3615735.

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Lang J, Maeda Y, Bannerman P, Xu J, Horiuchi M, Pleasure D, Guo F. Adenomatous polyposis coli regulates oligodendroglial development. J Neurosci. 2013 Feb 13;33(7):3113-30. doi: 10.1523/JNEUROSCI.3467-12.2013. PubMed PMID: 23407966; PubMed Central PMCID: PMC3711764.

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Pleasure D. GlyRα1, GAD65, amphiphysin, and gephyrin autoantibodies: leading or supporting roles in stiff-person disorders?. JAMA Neurol. 2013 Jan;70(1):16-7. doi: 10.1001/2013.jamaneurol.455. PubMed PMID: 23318510.

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Jiang P, Chen C, Wang R, Chechneva OV, Chung SH, Rao MS, Pleasure DE, Liu Y, Zhang Q, Deng W. hESC-derived Olig2+ progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury. Nat Commun. 2013;4:2196. doi: 10.1038/ncomms3196. PubMed PMID: 23880652; PubMed Central PMCID: PMC3903179.

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Horiuchi M, Wakayama K, Itoh A, Kawai K, Pleasure D, Ozato K, Itoh T. Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia. J Neuroinflammation. 2012 Sep 28;9:227. doi: 10.1186/1742-2094-9-227. PubMed PMID: 23020843; PubMed Central PMCID: PMC3546867.

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Sohn J, Selvaraj V, Wakayama K, Orosco L, Lee E, Crawford SE, Guo F, Lang J, Horiuchi M, Zarbalis K, Itoh T, Deng W, Pleasure D. PEDF is a novel oligodendrogenic morphogen acting on the adult SVZ and corpus callosum. J Neurosci. 2012 Aug 29;32(35):12152-64. doi: 10.1523/JNEUROSCI.0628-12.2012. PubMed PMID: 22933798; PubMed Central PMCID: PMC3457640.

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Lee E, Chanamara S, Pleasure D, Soulika AM. IFN-gamma signaling in the central nervous system controls the course of experimental autoimmune encephalomyelitis independently of the localization and composition of inflammatory foci. J Neuroinflammation. 2012 Jan 16;9:7. doi: 10.1186/1742-2094-9-7. PubMed PMID: 22248039; PubMed Central PMCID: PMC3293042.

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Guo F, Maeda Y, Ko EM, Delgado M, Horiuchi M, Soulika A, Miers L, Burns T, Itoh T, Shen H, Lee E, Sohn J, Pleasure D. Disruption of NMDA receptors in oligodendroglial lineage cells does not alter their susceptibility to experimental autoimmune encephalomyelitis or their normal development. J Neurosci. 2012 Jan 11;32(2):639-45. doi: 10.1523/JNEUROSCI.4073-11.2012. PubMed PMID: 22238099; PubMed Central PMCID: PMC3403747.

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Shen Y, Liu XB, Pleasure DE, Deng W. Axon-glia synapses are highly vulnerable to white matter injury in the developing brain. J Neurosci Res. 2012 Jan;90(1):105-21. doi: 10.1002/jnr.22722. Epub 2011 Aug 2. PubMed PMID: 21812016; PubMed Central PMCID: PMC3209489.

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Itoh T, Horiuchi M, Wakayama K, Itoh A, Pleasure D. [Demyelination and oligodendrocytes]. Rinsho Shinkeigaku. 2011 Nov;51(11):1036-9. doi: 10.5692/clinicalneurol.51.1036. Review. PubMed PMID: 22277471.

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Chechneva OV, Mayrhofer F, Daugherty DJ, Pleasure DE, Hong JS, Deng W. Low dose dextromethorphan attenuates moderate experimental autoimmune encephalomyelitis by inhibiting NOX2 and reducing peripheral immune cells infiltration in the spinal cord. Neurobiol Dis. 2011 Oct;44(1):63-72. doi: 10.1016/j.nbd.2011.06.004. Epub 2011 Jun 24. PubMed PMID: 21704706; PubMed Central PMCID: PMC3153572.

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Guo F, Maeda Y, Ma J, Delgado M, Sohn J, Miers L, Ko EM, Bannerman P, Xu J, Wang Y, Zhou C, Takebayashi H, Pleasure D. Macroglial plasticity and the origins of reactive astroglia in experimental autoimmune encephalomyelitis. J Neurosci. 2011 Aug 17;31(33):11914-28. doi: 10.1523/JNEUROSCI.1759-11.2011. PubMed PMID: 21849552; PubMed Central PMCID: PMC3167226.

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Ara J, Fekete S, Frank M, Golden JA, Pleasure D, Valencia I. Hypoxic-preconditioning induces neuroprotection against hypoxia-ischemia in newborn piglet brain. Neurobiol Dis. 2011 Aug;43(2):473-85. doi: 10.1016/j.nbd.2011.04.021. Epub 2011 Apr 30. PubMed PMID: 21554956.