NCBI
My NCBI
[Sign In]
[Register]
All Databases
PubMed
Nucleotide
Protein
Genome
Structure
OMIM
PMC
Journals
Books
Search
Database name
PubMed
Protein
Nucleotide
GSS
EST
Structure
Genome
BioSystems
Books
CancerChromosomes
Conserved Domains
dbGaP
3D Domains
Gene
Genome Project
GENSAT
GEO Profiles
GEO DataSets
HomoloGene
Journals
MeSH
NCBI Web Site
NLM Catalog
OMIA
OMIM
Peptidome
PMC
PopSet
Probe
Protein Clusters
PubChem BioAssay
PubChem Compound
PubChem Substance
SNP
SRA
Taxonomy
ToolKit
ToolKitAll
UniGene
UniSTS
for
Search term
Go
Clear
Save Search
Limits
Preview/Index
History
Clipboard
Details
Warning:
The NCBI web site requires JavaScript to function.
more...
Display
Summary
Brief
Overview
Protein FASTA
BioSystems
Gene Links
Genome Links
Nucleotide Links
EST Links
GSS Links
Protein Links
PubMed Links
PubMed (CDD) Links
PubMed (Curated) Links
PubMed (GeneRIF) Links
PubMed (By Homology) Links
PubMed (RefSeq) Links
PubMed (Structure) Links
PubMed (SwissProt) Links
Taxonomy Links
Show
5
10
20
50
100
200
500
Send to
Text
File
Printer
Clipboard
All: 1
Archaea: 0
Bacteria: 1
Curated: 1
Click to change filter selection through MyNCBI.
PRK09525
beta-D-galactosidase
Gene name:
lacZ
(Curated - Reviewed)
Cluster Info
ID :
419626
Total proteins :
62
Conserved in :
Bacteria
Total genera :
20
Total organisms :
62
Putative Paralogs :
0
Publications :
172
Cluster Tools
Show detailed alignment
Build tree
Genome ProtMap by PRK09525
Genome ProtMap by COG3250G
Cluster Patterns
Cross references
COG(s) :
COG3250G
EC Number :
3.2.1.23
HAMAP :
MF_01687
KEGG KO :
K01190
ACLAME :
family:all:853
InterPro :
8
TIGRFAM :
TIGR00262
Domain(s) :
3
Structures :
30
Entrez Links
BioSystems
Gene
Genome
Nucleotide
Protein
PubMed
PubMed (By Homology)
PubMed (CDD)
PubMed (Curated)
PubMed (GeneRIF)
PubMed (RefSeq)
PubMed (Structure)
PubMed (SwissProt)
Taxonomy
forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon
COG functional category:
Carbohydrate transport and metabolism
BRITE hierarchy:
Metabolism;Carbohydrate Metabolism;
Galactose metabolism
Glycan Biosynthesis and Metabolism;
Glycosaminoglycan degradation
Glycosphingolipid biosynthesis - ganglioseries
N-Glycan degradation
Lipid Metabolism;
Glycerolipid metabolism
Sphingolipid metabolism
Publications by categories
(only one publication per category is shown)
Publications by categories
(Show all 172)
Curated
[
1
]
:
Three-dimensional structure of beta-galactosidase from E. coli.Nature1994 Jun 30
more...
Curated
[
1
]
:
Three-dimensional structure of beta-galactosidase from E. coli.Nature1994 Jun 30
GeneRIF
[
5
]
:
Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli).Protein Sci2009 Jun
more...
GeneRIF
[
5
]
:
A study of the relationships of interactions between Asp-201, Na+ or K+, and galactosyl C6 hydroxyl and their effects on binding and reactivity of beta-galactosidase.Biochem Cell Biol2004 Apr
Changes to crystals of Escherichia coli beta-galactosidase during room-temperature/low-temperature cycling and their relation to cryo-annealing.Acta Crystallogr D Biol Crystallogr2007 Nov
Single molecule assays reveal differences between in vitro and in vivo synthesized beta-galactosidase.Protein J2008 Sep
Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli).Protein Sci2009 Jun
Amino acid sequence of beta-galactosidase. VIII. Sequence of the NH2-terminal segment, CNBr peptides 1 to 9, residues 1 to 377.J Biol Chem1978 Aug 10
RefSeq
[
123
]
:
Effect of DNA looping on the induction kinetics of the lac operon.J Theor Biol2007 Aug 21
more...
RefSeq
[
123
]
:
Ions, ion-pairs and catalysis by the lacZ beta-galactosidase of Escherichia coli.FEBS Lett1978 Oct 1
Probes of beta-galactosidase structure with antibodies. Reaction of anti-peptide antibodies against native enzyme.Biochemistry1978 Nov 28
Probe of beta-galactosidase structure with iodoacetate. Differential reactivity of thiol groups in wild-type and mutant forms of beta-galactosidase.Biochemistry1978 Nov 28
On-line monitoring of gene expression.Microbiology1999 Aug
beta-Galactosidase chimeras: primary structure of a lac repressor-beta-galactosidase protein.Proc Natl Acad Sci U S A1978 Oct
Eight UCA codons differentially affect the expression of the lacZ gene in the divE42 mutant of Escherichia coli.Can J Microbiol2000 Jun
Amino acid sequence of beta-galactosidase. IV. Sequence of an alpha-complementing cyanogen bromide peptide, residues 3 to 92.J Biol Chem1975 Apr 10
Molecular basis of beta-galactosidase alpha-complementation.Proc Natl Acad Sci U S A1975 Apr
High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.Protein Sci2000 Sep
Variable specific activity of Escherichia coli beta-galactosidase in bacterial cells.Biotechnol Bioeng2001 Feb 5
His-391 of beta-galactosidase (Escherichia coli) promotes catalyses by strong interactions with the transition state.Biochem Cell Biol2001
Reversible lattice repacking illustrates the temperature dependence of macromolecular interactions.J Mol Biol2001 Aug 24
The DnaK chaperone is necessary for alpha-complementation of beta-galactosidase in Escherichia coli.J Bacteriol2002 Dec
Trp-999 of beta-galactosidase (Escherichia coli) is a key residue for binding, catalysis, and synthesis of allolactose, the natural lac operon inducer.Biochemistry2003 Feb 18
Feedback regulation in the lactose operon: a mathematical modeling study and comparison with experimental data.Biophys J2003 May
Modeling network dynamics: the lac operon, a case study.J Cell Biol2003 May 12
The art and design of genetic screens: Escherichia coli.Nat Rev Genet2003 Jun
Gene replacement without selection: regulated suppression of amber mutations in Escherichia coli.Gene2003 Jun 5
Kinetics of transcription initiation at lacP1. Multiple roles of cyclic AMP receptor protein.J Biol Chem2003 Oct 10
Application of comparative genomics in the identification and analysis of novel families of membrane-associated receptors in bacteria.BMC Genomics2003 Aug 12
Growth rate regulation of lac operon expression in Escherichia coli is cyclic AMP dependent.FEBS Lett2003 Oct 23
Structural basis for the altered activity of Gly794 variants of Escherichia coli beta-galactosidase.Biochemistry2003 Nov 25
A rapid enzyme assay for beta-galactosidase using optically gated sample introduction on a microfabricated chip.Anal Bioanal Chem2004 Apr
Gene expression in Escherichia coli biofilms.Appl Microbiol Biotechnol2004 May
Multistability in the lactose utilization network of Escherichia coli.Nature2004 Feb 19
Amino acid sequence of beta-galactosidase. VI. Limited tryptic digestion of the citraconylated protein and sequences of tryptic peptides.J Biol Chem1978 Aug 10
Proteomic analysis of thioredoxin-targeted proteins in Escherichia coli.Proc Natl Acad Sci U S A2004 Mar 16
Distinct signatures for mutator sensitivity of lacZ reversions and for the spectrum of lacI/lacO forward mutations on the chromosome of nondividing Escherichia coli.Genetics2004 Feb
A facile and efficient method to achieve LacZ overproduction by the expression vector carrying the thermoregulated promoter and plasmid copy number.Biotechnol Prog2004 Mar-Apr
Programmed population control by cell-cell communication and regulated killing.Nature2004 Apr 22
Culture conditions differentially affect the translation of individual Escherichia coli mRNAs.J Mol Biol1992 Aug 5
Polarity effects in the lactose operon of Escherichia coli.J Mol Biol2004 May 21
Topological studies on the twin-arginine translocase component TatC.FEMS Microbiol Lett2004 May 15
Enhancement of translation initiation by A/T-rich sequences downstream of the initiation codon in Escherichia coli.J Mol Microbiol Biotechnol2003
Expression from the Escherichia coli dapA promoter is regulated by intracellular levels of diaminopimelic acid.FEMS Microbiol Lett2004 Jun 1
Dynamics and bistability in a reduced model of the lac operon.Chaos2004 Jun
Role of CH/pi interactions in substrate binding by Escherichia coli beta-galactosidase.Carbohydr Res2004 Sep 13
Evolution of specialists in an experimental microcosm.Genetics2004 Aug
Factors influencing preferential utilization of RNA polymerase containing sigma-38 in stationary-phase gene expression in Escherichia coli.J Microbiol2004 Jun
Highly phosphorylated bacterial proteins.Proteomics2004 Oct
A codon window in mRNA downstream of the initiation codon where NGG codons give strongly reduced gene expression in Escherichia coli.Nucleic Acids Res2004
Kinetic analysis of the oxidative conversion of the [4Fe-4S]2+ cluster of FNR to a [2Fe-2S]2+ Cluster.J Bacteriol2004 Dec
Adaptive amplification and point mutation are independent mechanisms: evidence for various stress-inducible mutation mechanisms.PLoS Biol2004 Dec
Lack of evidence for horizontal transfer of the lac operon into Escherichia coli.Mol Biol Evol2005 Mar
Activation of the gab operon in an RpoS-dependent manner by mutations that truncate the inner core of lipopolysaccharide in Escherichia coli.J Bacteriol2004 Dec
Association of RNA polymerase with transcribed regions in Escherichia coli.Proc Natl Acad Sci U S A2004 Dec 21
Positive selection system for identification of recombinants using alpha-complementation plasmids.Biotechniques2004 Dec
Effect of lac repressor oligomerization on regulatory outcome.Mol Microbiol1992 Apr
Folding of a misfolding-prone beta-galactosidase in absence of DnaK.Biotechnol Bioeng2005 Jun 30
The structure of E. coli beta-galactosidase.C R Biol2005 Jun
RNA polymerase structure and function at lac operon.C R Biol2005 Jun
[Gene knockout and knockin on the Escherichia coli lac operon loci using pBR322-red system]Sheng Wu Gong Cheng Xue Bao2005 Mar
Optimality and evolutionary tuning of the expression level of a protein.Nature2005 Jul 28
Site-saturation mutagenesis is more efficient than DNA shuffling for the directed evolution of beta-fucosidase from beta-galactosidase.J Mol Biol2005 Sep 23
A quantitative approach to catabolite repression in Escherichia coli.J Biol Chem2006 Feb 3
Effect of DNA structural flexibility on promoter strength--molecular dynamics studies of E. coli promoter sequences.Biochem Biophys Res Commun2006 Mar 10
Induction of the lac promoter in the absence of DNA loops and the stoichiometry of induction.Nucleic Acids Res2006
Guanosine 3',5'-bispyrophosphate coordinates global gene expression during glucose-lactose diauxie in Escherichia coli.Proc Natl Acad Sci U S A2006 Feb 14
Stochastic protein expression in individual cells at the single molecule level.Nature2006 Mar 16
Plasticity of the cis-regulatory input function of a gene.PLoS Biol2006 Apr
Predicting stochastic gene expression dynamics in single cells.Proc Natl Acad Sci U S A2006 May 9
Delivery of nitric oxide released from beta-Gal-NONOate activation by beta-galactosidase and its activity against Escherichia coli.Biol Pharm Bull2006 Jun
Effect of salt bridge on transcription activation of CRP-dependent lactose operon in Escherichia coli.Arch Biochem Biophys2006 Sep 15
Gentamicin and other cassettes for chromosomal gene replacement in Escherichia coli.Biotechniques2006 Sep
A direct and efficient PAGE-mediated overlap extension PCR method for gene multiple-site mutagenesis.Appl Microbiol Biotechnol2006 Nov
Transcription and decay of the lac messenger: role of an intergenic terminator.J Bacteriol1991 Jan
Rational design and rapid screening of antisense oligonucleotides for prokaryotic gene modulation.Nucleic Acids Res2006
Beta-galactosidase (Escherichia coli) has a second catalytically important Mg2+ site.Biochem Biophys Res Commun2007 Jan 12
Amplification of lac cannot account for adaptive mutation to Lac+ in Escherichia coli.J Bacteriol2007 Mar
RNA visualization in live bacterial cells using fluorescent protein complementation.Nat Methods2007 May
Effect of DNA looping on the induction kinetics of the lac operon.J Theor Biol2007 Aug 21
Distinctive patterns of translational reinitiation in the lac repressor mRNA: bridging of long distances by out-of-frame translation and RNA secondary structure, effects of primary sequence.Nucleic Acids Res1991 Jul 11
Determination of the roles of Glu-461 in beta-galactosidase (Escherichia coli) using site-specific mutagenesis.J Biol Chem1990 Apr 5
Mapping the lacZ ribosome binding site by RNA footprinting.Biochemistry1989 Oct 3
Activation of the lac promoter and its variants. Synergistic effects of catabolite activator protein and supercoiling in vitro.J Mol Biol1989 Jun 20
The amino acid sequence of beta-galactosidase of Escherichia coli.Proc Natl Acad Sci U S A1977 Apr
Position of the mutation in beta-galactosidase ochre mutant U118.J Bacteriol1978 Jan
On the evolution of beta-galactosidase.Proc Natl Acad Sci U S A1978 Jan
High resolution colony staining for the detection of bacterial growth requirement mutants using naphthol azo-dye techniques.Biochem Biophys Res Commun1965 Oct 26
The amino acid sequence of -galactosidase. II. Tryptic peptides of the maleylated protein and sequences of some tryptic peptides.J Biol Chem1972 Sep 10
The amino acid sequence of -galactosidase. 3. The sequences of NH 2 - and COOH-terminal tryptic peptides.J Biol Chem1972 Sep 10
High-level production of -galactosidase by Escherichia coli merodiploids.J Bacteriol1972 Nov
Selective autocytotoxicity in a model system of Escherichia coli K-12 recombinants.J Bacteriol1973 May
Inhibition of lacZ gene translation initiation in trp-lac fusion strains.J Bacteriol1974 Mar
Lac repressor can be fused to beta-galactosidase.Nature1974 Jun 7
Sequential transcription and translation in the lactose operon of Escherichia coli.Biochim Biophys Acta1967 Mar 29
Dependence of beta-galactoside-transacetylase activity on the temperature of growth in E. coli strains with polar mutations in the operator-proximal part of the beta-galactosidase gene.Biochem Biophys Res Commun1967 Dec 15
Transposition of the lac region of Escherichia coli. IV. Escape from repression in bacteriophage-carried lac genes.J Mol Biol1967 Dec 28
Relationships between the regulation of the lactose and galactose operons of Escherichia coli.J Bacteriol1969 Feb
Re-initiation of polypeptide synthesis and polarity in the lac operon of Escherichia coli.J Mol Biol1969 May 14
Classification and intragenic position of mutations in the beta-galactosidase gene of Escherichia coli.Mol Gen Genet1969
Catabolite repression of the lac operon. The contribution f trascriptional repression.Biochem J1969 Sep
Catabolite repression of the lac operon. Separt epressionof two enzymes.Biochem J1969 Sep
Biochemical evidence that the operator locus is distinct from the z gene in the lac operon of Escherichia coli.J Mol Biol1969 Jul 14
Mutations conferring quantitative and qualitative increases in beta-galactosidase activity in Escherichia coli.Mol Gen Genet1969
Induction of the lactose transport system in a lipid-synthesis-defective mutant of Escherichia coli.J Bacteriol1970 Aug
The amino acid sequence of beta galactosidase. I. Isolation and composition of tryptic peptides.J Biol Chem1970 Oct 10
Co-linearity of beta-galactosidase with its gene by immunological detection of incomplete polypeptide chains.Science1966 Nov 25
Synthesis, utilization and degradation of lactose operon mRNA in Escherichia coli.J Mol Biol1967 Mar 14
Beta-galactosidase: immunological studies of nonsense, missense and deletion mutants.J Mol Biol1968 Apr 14
Beta-galactosidase: isolation of and antibodies to incomplete chains.J Bacteriol1970 Feb
[Role of transgalactosidations in induction of the lactose operon in Escherichia coli]Bull Soc Chim Biol (Paris)1965
Sequential transcription of the genes of the lactose operon and its regulation by protein synthesis.J Biol Chem1966 Oct 10
Regulation of the lac operon. Recent studies on the regulation of lactose metabolism in Escherichia coli support the operon model.Science1967 May 5
Synthesis of enzymes of the lactose operon during diauxic growth of Escherichia coli.Biochem Biophys Res Commun1966 Aug 23
Transposition of the lac region of Escherichia coli. I. Inversion of the lac operon and transduction of lac by phi80.J Mol Biol1966 Aug
Orientation of nonsense codons on the genetic map of the lac operon.Science1967 Sep 8
A partial restriction map of the proA-purE region of the Escherichia coli K12 chromosome.Gene1983 May-Jun
Purification, structure, and properties of hybrid beta-galactosidase proteins.J Biol Chem1983 Dec 10
beta-galactosidase omega-complementation with a small cyanogen bromide peptide.Biochem Biophys Res Commun1980 Mar 13
Positions of early nonsense and deletion mutations in lacZ.J Bacteriol1980 May
A mutant Ebg enzyme that converts lactose into an inducer of the lac operon.J Bacteriol1980 Jun
beta-Galactosidase alpha-complementation. Overlapping sequences.J Biol Chem1981 Jul 10
beta-Galactosidase alpha-complementation. Effect of single amino acid substitutions.J Biol Chem1981 Jul 10
Position of the lacZX90 mutation and hybridization between complete and incomplete beta-galactosidase.J Bacteriol1981 Aug
Inactivation of beta-Galactosidase by iodination of tyrosine-253.Biochemistry1982 Sep 28
The stability of Escherichia coli lacZ mRNA depends upon the simultaneity of its synthesis and translation.EMBO J1995 Jul 3
Unequal fidelity of leading strand and lagging strand DNA replication on the Escherichia coli chromosome.Proc Natl Acad Sci U S A1998 Aug 18
Methionine 500, the site of covalent attachment of an active site-directed reagent of beta-galactosidase.J Biol Chem1978 Aug 10
Amino acid sequence of beta-galactosidase. V. Isolation and sequences of chymotryptic peptides.J Biol Chem1978 Aug 10
Amino acid sequence of beta-galactosidase. VII. Isolation of the 24 cyanogen bromide peptides.J Biol Chem1978 Aug 10
Amino acid sequence of beta-galactosidase. IX. Sequence of the central segment, CNBr peptides 10 to 17, residues 378 to 653.J Biol Chem1978 Aug 10
Amino acid sequence of beta-galactosidase. X. Sequence of the COOH-terminal segment, CNBr peptides 18 to 24, residues 654 to 1021.J Biol Chem1978 Aug 10
SwissProt
[
13
]
:
His-357 of beta-galactosidase (Escherichia coli) interacts with the C3 hydroxyl in the transition state and helps to mediate catalysis.Biochemistry1998 Jul 14
more...
SwissProt
[
13
]
:
Interaction of divalent cations with beta-galactosidase (Escherichia coli).Biochemistry1979 Sep 18
Glu-537, not Glu-461, is the nucleophile in the active site of (lac Z) beta-galactosidase from Escherichia coli.J Biol Chem1992 Jun 5
lac Repressor-operator interaction. VI. The natural inducer of the lac operon.J Mol Biol1972 Aug 28
Molecular consequences of deletion formation mediated by the transposon Tn9.Nature1980 May 1
Sequence of the lacZ gene of Escherichia coli.EMBO J1983
The active site regions of lacZ and ebg beta-galactosidases are homologous.J Biol Chem1983 Sep 10
Identification of an essential carboxylate group at the active site of lacZ beta-galactosidase from Escherichia coli.Eur J Biochem1984 Feb 1
Sequence of the lactose permease gene.Nature1980 Feb 7
E461H-beta-galactosidase (Escherichia coli): altered divalent metal specificity and slow but reversible metal inactivation.Biochemistry1995 Oct 17
The beta-galactosidase (Escherichia coli) reaction is partly facilitated by interactions of His-540 with the C6 hydroxyl of galactose.J Biol Chem1996 Jun 14
Cloning, DNA sequence, and regulation of expression of a gene encoding beta-galactosidase from Lactococcus lactis.DNA Seq1996
His-357 of beta-galactosidase (Escherichia coli) interacts with the C3 hydroxyl in the transition state and helps to mediate catalysis.Biochemistry1998 Jul 14
Amino acid sequence of beta-galactosidase. XI. Peptide ordering procedures and the complete sequence.J Biol Chem1978 Aug 10
By Homology
[
27
]
:
pMH11, A tool for gene disruption and expression analysis in Azorhizobium caulinodans.Plasmid2002 Mar
more...
By Homology
[
27
]
:
pMH11, A tool for gene disruption and expression analysis in Azorhizobium caulinodans.Plasmid2002 Mar
Intermediates in transcription initiation from the E. coli lac UV5 promoter.Cell1985 Dec
A frameshift mutation at the junction of an IS1 insertion within lacZ restores beta-galactosidase activity via formation of an active lacZ-IS1 fusion protein.J Mol Biol1985 Feb 20
lac Up-promoter mutants with increased homology to the consensus promoter sequence.J Bacteriol1985 Dec
Nucleotide sequence changes produced by mutations in the lac promoter of Escherichia coli.J Mol Biol1977 Mar 25
Correlation of nonsense sites in the lacI gene with specific codons in the nucleotide sequence.Nature1978 Aug 24
Changes in the DNA structure of the lac UV5 promoter during formation of an open complex with Escherichia coli RNA polymerase.Biochemistry1985 May 21
Effects of heterologous ribosomal binding sites on the transcription and translation of the lacZ gene of Escherichia coli.Gene1985
The nucleotide sequence of the lactose messenger ribonucleic acid transcribed from the UV5 promoter mutant of Escherichia coli.Proc Natl Acad Sci U S A1973 Dec
Sequences of controlling regions of the lactose operon.Cold Spring Harb Symp Quant Biol1974
Cloning and characterization of the natural lactose operator.Gene1981 Jan-Feb
Genetic and sequencing studies of the specificity of transposition into the lac region of E. coli.Cold Spring Harb Symp Quant Biol1981
Variants of a cloned synthetic lactose operator. II. Chloramphenicol-resistant revertants retaining a lactose operator in the CAT gene of plasmid pBR325.Gene1981 Nov
Mutations in the lacY gene of Escherichia coli define functional organization of lactose permease.Proc Natl Acad Sci U S A1981 Dec
A termination site for LacI transcription is between the CAP site and the lac promoter.J Biol Chem1982 Oct 10
Effects of neighboring DNA homopolymers on the biochemical and physical properties of the Escherichia coli lactose promoter. I. Cloning and characterization studies.J Biol Chem1982 Nov 10
Construction and analysis of in vivo activity of E. coli promoter hybrids and promoter mutants that alter the -35 to -10 spacing.Gene1982 Dec
Footprinting with MPE.Fe(II). Complementary-strand analyses of distamycin- and actinomycin-binding sites on heterogeneous DNA.Cold Spring Harb Symp Quant Biol1983
Lac repressor mRNA transcription terminates in vivo in the lac control region.J Biol Chem1983 Sep 25
A perfectly symmetric lac operator binds the lac repressor very tightly.Proc Natl Acad Sci U S A1983 Nov
Structural intermediates of deletion mutagenesis: a role for palindromic DNA.Proc Natl Acad Sci U S A1984 Jan
DNA sequence alteration resulting from a mutation impairing promoter function in the lac repressor gene.Mol Gen Genet1980 Apr
Variants of a cloned synthetic lactose operator. I. A palindromic dimer lactose operator derived from one stand of the cloned 40-base pair operator.Gene1981 Jan-Feb
Topography of interaction of Escherichia coli RNA polymerase subunits with lac UV5 promoter.FEBS Lett1981 Jun 1
The DNA sequence change resulting from the IQ1 mutation, which greatly increases promoter strength.Mol Gen Genet1981
Segment-specific mutagenesis: extensive mutagenesis of a lac promoter/operator element.Proc Natl Acad Sci U S A1982 Mar
Structure of the lactose operator.Nature1976 Mar 25
CDD
[
1
]
:
Three-dimensional structure of beta-galactosidase from E. coli.Nature1994 Jun 30
more...
CDD
[
1
]
:
Three-dimensional structure of beta-galactosidase from E. coli.Nature1994 Jun 30
Structure
[
7
]
:
Structural basis for the altered activity of Gly794 variants of Escherichia coli beta-galactosidase.Biochemistry2003 Nov 25
more...
Structure
[
7
]
:
Structural comparisons of TIM barrel proteins suggest functional and evolutionary relationships between beta-galactosidase and other glycohydrolases.Protein Sci1999 Jan
High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.Protein Sci2000 Sep
Reversible lattice repacking illustrates the temperature dependence of macromolecular interactions.J Mol Biol2001 Aug 24
A structural view of the action of Escherichia coli (lacZ) beta-galactosidase.Biochemistry2001 Dec 11
Structural basis for the altered activity of Gly794 variants of Escherichia coli beta-galactosidase.Biochemistry2003 Nov 25
Crystallization of beta-galactosidase from Escherichia coli.J Mol Biol1992 Feb 20
Three-dimensional structure of beta-galactosidase from E. coli.Nature1994 Jun 30
Top Pattern:
PRK09526
PRK09525
PRK09528
PRK09527
Organism
(Collapse)
(Highlight paralogs)
(Limit to paralogs)
Protein name
Prev. Cluster
Accession
Next Cluster
Locus_tag
Length
BLink
Alignment
Identical sequences are framed
J.Firmicutes
Lactococcus lactis subsp. lactis Il1403
Lactococcus (1 proteins)
beta-D-galactosidase
PRK05270
NP_268137
CLS992964
L0025
998aa
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
Leuconostoc (1 proteins)
beta-D-galactosidase
CLS1234159
YP_818785
CLS1225721
LEUM_1316
1036aa
Oenococcus oeni PSU-1
Oenococcus (1 proteins)
beta-D-galactosidase
CLS898310
YP_810613
CLS971925
OEOE_1044
1031aa
R.Gammaproteobacteria
Aeromonas hydrophila subsp. hydrophila ATCC 7966
Aeromonas (1 proteins)
beta-D-galactosidase
CLS1060008
YP_858525
CLS1183137
AHA_4101
1025aa
Alteromonas macleodii 'Deep ecotype'
Alteromonas (1 proteins)
beta-D-galactosidase
CLS2191788
YP_002124587
PRK11173
MADE_00275
1041aa
Citrobacter koseri ATCC BAA-895
Citrobacter (1 proteins)
beta-D-galactosidase
PRK09526
YP_001454367
PRK10524
CKO_02825
1025aa
Cronobacter sakazakii ATCC BAA-894
Cronobacter (1 proteins)
beta-D-galactosidase
PRK09526
YP_001439042
CLS1305028
ESA_02977
1043aa
Enterobacter sp. 638
Enterobacter (1 proteins)
beta-D-galactosidase
PRK09526
YP_001175663
CLS1195698
Ent638_0928
1028aa
Erwinia tasmaniensis Et1/99
Erwinia (1 proteins)
beta-D-galactosidase
PRK11880
YP_001908490
CLS2218852
ETA_25680
1026aa
Escherichia coli 536
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_668349
PRK09528
ECP_0417
1024aa
Escherichia coli 55989
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_002401475
PRK09528
EC55989_0351
1024aa
Escherichia coli APEC O1
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_851535
PRK09528
APECO1_1649
1024aa
Escherichia coli ATCC 8739
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_001726230
PRK09528
EcolC_3281
1024aa
Escherichia coli BW2952
Escherichia (22 proteins)
beta-D-galactosidase
PRK04346
YP_002928937
PRK09528
BWG_3744
1080aa
Escherichia coli CFT073
Escherichia (22 proteins)
beta-D-galactosidase
CLS1213835
NP_752394
PRK09528
c0459
1024aa
Escherichia coli E24377A
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_001461520
PRK09528
EcE24377A_0368
1024aa
Escherichia coli ED1a
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_002396427
PRK09528
ECED1_0372
1024aa
Escherichia coli HS
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_001457178
PRK09528
EcHS_A0408
1024aa
Escherichia coli IAI1
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_002385823
PRK09528
ECIAI1_0345
1024aa
Escherichia coli IAI39
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_002406376
PRK09528
ECIAI39_0334
1024aa
Escherichia coli O127:H6 str. E2348/69
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_002327878
PRK09528
E2348C_0299
1024aa
Escherichia coli O157:H7 str. EC4115
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_002268983
PRK09528
ECH74115_0417
1024aa
Escherichia coli SE11
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_002291644
PRK09528
ECSE_0369
1024aa
Escherichia coli SMS-3-5
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_001742478
PRK09528
EcSMS35_0375
1024aa
Escherichia coli UMN026
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_002411150
PRK09528
ECUMN_0387
1024aa
Escherichia coli str. K-12 substr. MG1655
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
NP_414878
PRK09528
b0344
1024aa
Escherichia fergusonii ATCC 35469
Escherichia (22 proteins)
beta-D-galactosidase
CLS1229421
YP_002383762
PRK10524
EFER_2656
1077aa
Escherichia coli O157:H7 EDL933
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
NP_286085
PRK09528
Z0440
1024aa
Escherichia coli O157:H7 str. Sakai
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
NP_308424
PRK09528
ECs0397
1024aa
Escherichia coli S88
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_002390181
PRK09528
ECS88_0351
1024aa
Escherichia coli UTI89
Escherichia (22 proteins)
beta-D-galactosidase
PRK09526
YP_539403
PRK09528
UTI89_C0371
1024aa
Klebsiella pneumoniae (plasmid)
Klebsiella (5 proteins)
beta-D-galactosidase
PRK09526
YP_001965915
PRK09528
pK29_p245
1024aa
Klebsiella pneumoniae 342
Klebsiella (5 proteins)
beta-D-galactosidase
PRK09526
YP_002238606
CLS1305028
KPK_2776
1035aa
Klebsiella pneumoniae NTUH-K2044
Klebsiella (5 proteins)
beta-D-galactosidase
PRK09526
YP_002919371
CLS1305028
KP1_2639
1035aa
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Klebsiella (5 proteins)
beta-D-galactosidase
PRK09526
YP_001335271
CLS1305028
KPN_01610
1035aa
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (plasmid)
Klebsiella (5 proteins)
beta-D-galactosidase
PRK09526
YP_001338480
PRK09528
KPN_pKPN3p05871
1024aa
Pectobacterium atrosepticum SCRI1043
Pectobacterium (1 proteins)
beta-D-galactosidase
PRK09526
YP_049595
PRK09528
ECA1490
1040aa
Photobacterium profundum SS9
Photobacterium (1 proteins)
beta-D-galactosidase
CLS1179714
YP_131707
CLS2170818
PBPRB0034
1030aa
Psychromonas ingrahamii 37
Psychromonas (1 proteins)
beta-D-galactosidase
PRK05101
YP_943382
CLS1270741
Ping_2019
1035aa
Salmonella enterica subsp. arizonae serovar 62:z4,z23:--
Salmonella (1 proteins)
beta-D-galactosidase
PRK09526
YP_001571822
PRK09528
SARI_02832
1027aa
Serratia proteamaculans 568
Serratia (1 proteins)
beta-D-galactosidase
CLS1291513
YP_001479401
PRK12921
Spro_3173
1029aa
Shigella dysenteriae Sd197
Shigella (2 proteins)
beta-D-galactosidase
PRK09526
YP_402080
CLS1173282
SDY_0378
969aa
Shigella sonnei Ss046
Shigella (2 proteins)
beta-D-galactosidase
PRK09526
YP_309314
CLS727798
SSON_0299
1024aa
Tolumonas auensis DSM 9187
Tolumonas (1 proteins)
glycoside hydrolase family 2 TIM barrel
PRK11072
YP_002894085
CLS1183187
Tola_2910
1025aa
Vibrio vulnificus CMCP6
Vibrio (6 proteins)
beta-D-galactosidase
CLS1207177
NP_763225
CLS1183137
VV2_1327
1032aa
Vibrio vulnificus YJ016
Vibrio (6 proteins)
beta-D-galactosidase
CLS1207177
NP_936221
CLS1183137
VVA0165
1031aa
Vibrio cholerae M66-2
Vibrio (6 proteins)
beta-galactosidase
CLS1189390
YP_002811013
CLS1189389
VCM66_2261
1044aa
Vibrio cholerae MJ-1236
Vibrio (6 proteins)
beta-galactosidase
CLS1189390
YP_002877749
CLS1189389
VCD_002010
1044aa
Vibrio cholerae O395
Vibrio (6 proteins)
beta-D-galactosidase
CLS1189390
YP_001217841
CLS1189389
VC0395_A1917
1044aa
Vibrio cholerae O395
Vibrio (6 proteins)
beta-galactosidase
CLS1189390
YP_002820679
CLS1189389
VC395_2453
1044aa
Yersinia enterocolitica subsp. enterocolitica 8081
Yersinia (12 proteins)
beta-D-galactosidase
PRK09526
YP_001006792
CLS1065308
YE2592
1050aa
Yersinia pestis Angola
Yersinia (12 proteins)
beta-D-galactosidase
PRK10708
YP_001607216
CLS1207206
YpAngola_A2834
1050aa
Yersinia pseudotuberculosis IP 31758
Yersinia (12 proteins)
beta-D-galactosidase
PRK10708
YP_001400606
CLS1207206
YpsIP31758_1629
1066aa
Yersinia pestis Antiqua
Yersinia (12 proteins)
beta-D-galactosidase
CLS1173274
YP_651779
CLS1207206
YPA_1868
1060aa
Yersinia pestis CO92
Yersinia (12 proteins)
beta-D-galactosidase
CLS1207207
YP_002346664
CLS1207206
YPO1654
1060aa
Yersinia pestis KIM
Yersinia (12 proteins)
beta-D-galactosidase
PRK10708
NP_669134
CLS1207206
y1817
1060aa
Yersinia pestis Nepal516
Yersinia (12 proteins)
beta-D-galactosidase
CLS1207207
YP_647904
CLS1207206
YPN_1975
1060aa
Yersinia pestis Pestoides F
Yersinia (12 proteins)
beta-D-galactosidase
CLS1207207
YP_001163150
CLS1207206
YPDSF_1792
1060aa
Yersinia pestis biovar Microtus str. 91001
Yersinia (12 proteins)
beta-D-galactosidase
CLS1207207
NP_993135
CLS1207206
YP_1785
1060aa
Yersinia pseudotuberculosis IP 32953
Yersinia (12 proteins)
beta-D-galactosidase
CLS1207207
YP_070928
CLS1207206
YPTB2415
1066aa
Yersinia pseudotuberculosis PB1/+
Yersinia (12 proteins)
beta-D-galactosidase
CLS1207207
YP_001872912
CLS2225518
YPTS_2494
1066aa
Yersinia pseudotuberculosis YPIII
Yersinia (12 proteins)
beta-D-galactosidase
CLS1207207
YP_001720485
CLS2225518
YPK_1739
1066aa
Display
Summary
Brief
Overview
Protein FASTA
BioSystems
Gene Links
Genome Links
Nucleotide Links
EST Links
GSS Links
Protein Links
PubMed Links
PubMed (CDD) Links
PubMed (Curated) Links
PubMed (GeneRIF) Links
PubMed (By Homology) Links
PubMed (RefSeq) Links
PubMed (Structure) Links
PubMed (SwissProt) Links
Taxonomy Links
Show
5
10
20
50
100
200
500
Send to
Text
File
Printer
Clipboard
Write to the Help Desk
NCBI
|
NLM
|
NIH
Department of Health & Human Services
Privacy Statement
|
Freedom of Information Act
|
Disclaimer