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Did you mean welman ke (6 results)?
Determinants of plasma water sodium concentration as reflected in the Edelman equation: role of osmotic and Gibbs-Donnan equilibrium.
Nguyen MK, Kurtz I. Nguyen MK, et al. Am J Physiol Renal Physiol. 2004 May;286(5):F828-37. doi: 10.1152/ajprenal.00393.2003. Epub 2004 Jan 20. Am J Physiol Renal Physiol. 2004. PMID: 15075178 Free article. Review.
Edelman et al. have empirically shown that plasma water sodium concentration ([Na(+)](pw)) is equal to 1.11(Na(e) + K(e))/TBW - 25.6 (Edelman IS, Leibman J, O'Meara MP, Birkenfeld LW. ...In addition, we demonstrate quantitatively the physiological significance of th …
Edelman et al. have empirically shown that plasma water sodium concentration ([Na(+)](pw)) is equal to 1.11(Na(e) + K(e))/TBW - 25.6 …
Osmotically inactive sodium and potassium storage: lessons learned from the Edelman and Boling data.
Nguyen MK, Nguyen DS, Nguyen MK. Nguyen MK, et al. Am J Physiol Renal Physiol. 2016 Sep 1;311(3):F539-47. doi: 10.1152/ajprenal.00215.2016. Epub 2016 Jun 8. Am J Physiol Renal Physiol. 2016. PMID: 27279486 Free article.
Because changes in the plasma water sodium concentration ([Na(+)]pw) are clinically due to changes in the mass balance of Na(+), K(+), and H2O, the analysis and treatment of the dysnatremias are dependent on the validity of the Edelman equation in defining the quantitative …
Because changes in the plasma water sodium concentration ([Na(+)]pw) are clinically due to changes in the mass balance of Na(+), K(+), and H …
Quantitative approaches to the analysis and treatment of the dysnatremias.
Nguyen MK. Nguyen MK. Semin Nephrol. 2009 May;29(3):216-26. doi: 10.1016/j.semnephrol.2009.03.006. Semin Nephrol. 2009. PMID: 19523570 Review.
Central to these recent advances is the recognition of the full significance of the Edelman equation discovered 50 years ago. Although Edelman et al showed empirically that the [Na(+)](pw) is related to the total exchangeable sodium (Na(e)), total exchangeable potas …
Central to these recent advances is the recognition of the full significance of the Edelman equation discovered 50 years ago. Althoug …
Role of potassium in hypokalemia-induced hyponatremia: lessons learned from the Edelman equation.
Nguyen MK, Kurtz I. Nguyen MK, et al. Clin Exp Nephrol. 2004 Jun;8(2):98-102. doi: 10.1007/s10157-004-0281-3. Clin Exp Nephrol. 2004. PMID: 15235925
It is well known that changes in the mass balance of K+ can lead to an alteration in the plasma water sodium concentration ([Na+]pw). We have recently shown that based on the Edelman equation, the [Na+]pw is determined by the total exchangeable Na+ (Nae), total exchangeabl …
It is well known that changes in the mass balance of K+ can lead to an alteration in the plasma water sodium concentration ([Na+]pw). We hav …
New insights into the pathophysiology of the dysnatremias: a quantitative analysis.
Nguyen MK, Kurtz I. Nguyen MK, et al. Am J Physiol Renal Physiol. 2004 Aug;287(2):F172-80. doi: 10.1152/ajprenal.00106.2004. Am J Physiol Renal Physiol. 2004. PMID: 15271684 Free article. Review.
Central to these considerations is the original empirical relationship between the [Na(+)](pw) and total exchangeable sodium (Na(e)), total exchangeable potassium (K(e)), and total body water (TBW) initially discovered by Edelman and colleagues (Edelman IS, Leibman …
Central to these considerations is the original empirical relationship between the [Na(+)](pw) and total exchangeable sodium (Na(e)), total …
Evolving concepts in the quantitative analysis of the determinants of the plasma water sodium concentration and the pathophysiology and treatment of the dysnatremias.
Kurtz I, Nguyen MK. Kurtz I, et al. Kidney Int. 2005 Nov;68(5):1982-93. doi: 10.1111/j.1523-1755.2005.00652.x. Kidney Int. 2005. PMID: 16221198 Free article. Review.
The physiologic and clinical implications of the empirical formula originally discovered by Edelman et al [J Clin Invest 37:1236-1256, 1958] relating the plasma water sodium concentration ([Na(+)](pw)) to the total exchangeable sodium (Na(e)), total exchangeable potassium …
The physiologic and clinical implications of the empirical formula originally discovered by Edelman et al [J Clin Invest 37:1236-1256 …
Derivation of a new formula for calculating urinary electrolyte-free water clearance based on the Edelman equation.
Nguyen MK, Kurtz I. Nguyen MK, et al. Am J Physiol Renal Physiol. 2005 Jan;288(1):F1-7. doi: 10.1152/ajprenal.00259.2004. Epub 2004 Sep 21. Am J Physiol Renal Physiol. 2005. PMID: 15383402 Free article.
MEFWC, unlike previous formulas, is derived based on the requirement of the Edelman equation that urine is isonatric only when [Na(+) + K(+)](urine) = (Na(e) + K(e))/TBW = 0.97[Na(+)](p) + 23.1. Furthermore, since we have shown that the y-intercept in the Edelman eq …
MEFWC, unlike previous formulas, is derived based on the requirement of the Edelman equation that urine is isonatric only when [Na(+) …
Structure-guided combination therapy to potently improve the function of mutant CFTRs.
Veit G, Xu H, Dreano E, Avramescu RG, Bagdany M, Beitel LK, Roldan A, Hancock MA, Lay C, Li W, Morin K, Gao S, Mak PA, Ainscow E, Orth AP, McNamara P, Edelman A, Frenkiel S, Matouk E, Sermet-Gaudelus I, Barnes WG, Lukacs GL. Veit G, et al. Nat Med. 2018 Nov;24(11):1732-1742. doi: 10.1038/s41591-018-0200-x. Epub 2018 Oct 8. Nat Med. 2018. PMID: 30297908 Free PMC article.
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