PubMed

Are astrocytes the missing link between lack of brain aspartoacylase activity and the spongiform leukodystrophy in Canavan disease?

Baslow MH, Guilfoyle DN.

Neurochem Res. 2009 Sep;34(9):1523-34. Epub 2009 Mar 25.PMID: 19319678 [PubMed - indexed for MEDLINE]Related articles

Reliable prenatal diagnosis of Canavan disease by measuring N-acetylaspartate in amniotic fluid using liquid chromatography tandem mass spectrometry.

Al-Dirbashi OY, Kurdi W, Imtiaz F, Ahmad AM, Al-Sayed M, Tulbah M, Al-Nemer M, Rashed MS.

Prenat Diagn. 2009 May;29(5):477-80.PMID: 19235826 [PubMed - indexed for MEDLINE]Related articles

Genome-wide gene expression profiling and mutation analysis of Saudi patients with Canavan disease.

Kaya N, Imtiaz F, Colak D, Al-Sayed M, Al-Odaib A, Al-Zahrani F, Al-Mubarak BR, Al-Owain M, Al-Dhalaan H, Chedrawi A, Al-Hassnan Z, Coskun S, Sakati N, Ozand P, Meyer BF.

Genet Med. 2008 Sep;10(9):675-84.PMID: 18978679 [PubMed - indexed for MEDLINE]Related articles

Novel mutation of aspartoacylase gene in a Turkish patient with Canavan disease.

Unalp A, Altiok E, Uran N, Oztürk A, Yüksel S.

J Trop Pediatr. 2008 Jun;54(3):208-10. Epub 2007 Nov 12.PMID: 17999961 [PubMed - indexed for MEDLINE]Related articles

Quantification of N-acetylaspartic acid in urine by LC-MS/MS for the diagnosis of Canavan disease.

Al-Dirbashi OY, Rashed MS, Al-Qahtani K, Al-Mokhadab MA, Kurdi W, Al-Sayed MA.

J Inherit Metab Dis. 2007 Aug;30(4):612. Epub 2007 Jul 12.PMID: 17632691 [PubMed - indexed for MEDLINE]Related articles

Mutational analysis of aspartoacylase: implications for Canavan disease.

Hershfield JR, Pattabiraman N, Madhavarao CN, Namboodiri MA.

Brain Res. 2007 May 7;1148:1-14. Epub 2007 Mar 3.PMID: 17391648 [PubMed - indexed for MEDLINE]Related articlesFree article

Restricted diffusion in Canavan disease.

Srikanth SG, Chandrashekar HS, Nagarajan K, Jayakumar PN.

Childs Nerv Syst. 2007 Apr;23(4):465-8. Epub 2007 Jan 12.PMID: 17219235 [PubMed - indexed for MEDLINE]Related articles

Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.

Bitto E, Bingman CA, Wesenberg GE, McCoy JG, Phillips GN Jr.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):456-61. Epub 2006 Dec 28.PMID: 17194761 [PubMed - indexed for MEDLINE]Related articlesFree article

Natural history of Canavan disease revealed by proton magnetic resonance spectroscopy (1H-MRS) and diffusion-weighted MRI.

Janson CG, McPhee SW, Francis J, Shera D, Assadi M, Freese A, Hurh P, Haselgrove J, Wang DJ, Bilaniuk L, Leone P.

Neuropediatrics. 2006 Aug;37(4):209-21.PMID: 17177147 [PubMed - indexed for MEDLINE]Related articles

Identification of the zinc binding ligands and the catalytic residue in human aspartoacylase, an enzyme involved in Canavan disease.

Herga S, Berrin JG, Perrier J, Puigserver A, Giardina T.

FEBS Lett. 2006 Oct 30;580(25):5899-904. Epub 2006 Oct 2.PMID: 17027983 [PubMed - indexed for MEDLINE]Related articles

Case 99: Canavan disease.

Michel SJ, Given CA 2nd.

Radiology. 2006 Oct;241(1):310-4. No abstract available. PMID: 16990683 [PubMed - indexed for MEDLINE]Related articlesFree article

Rapid detection of three large novel deletions of the aspartoacylase gene in non-Jewish patients with Canavan disease.

Zeng BJ, Wang ZH, Torres PA, Pastores GM, Leone P, Raghavan SS, Kolodny EH.

Mol Genet Metab. 2006 Sep-Oct;89(1-2):156-63. Epub 2006 Jul 18.PMID: 16854607 [PubMed - indexed for MEDLINE]Related articles

Canavan disease: a white matter disorder.

Kumar S, Mattan NS, de Vellis J.

Ment Retard Dev Disabil Res Rev. 2006;12(2):157-65. Review.PMID: 16807907 [PubMed - indexed for MEDLINE]Related articles

Does ASPA gene mutation in Canavan disease alter oligodendrocyte development? A tissue culture study of ASPA KO mice brain.

Kumar S, Sowmyalakshmi R, Daniels SL, Chang R, Surendran S, Matalon R, de Vellis J.

Adv Exp Med Biol. 2006;576:175-82; discussion 361-3. No abstract available. PMID: 16802712 [PubMed - indexed for MEDLINE]Related articles

Mutation analysis of the aspartoacylase gene in non-Jewish patients with Canavan disease.

Zeng BJ, Pastores GM, Leone P, Raghavan S, Wang ZH, Ribeiro LA, Torres P, Ong E, Kolodny EH.

Adv Exp Med Biol. 2006;576:165-73; discussion 361-3. No abstract available. PMID: 16802711 [PubMed - indexed for MEDLINE]Related articles

Defective myelin lipid synthesis as a pathogenic mechanism of Canavan disease.

Namboodiri AM, Moffett JR, Arun P, Mathew R, Namboodiri S, Potti A, Hershfield J, Kirmani B, Jacobowitz DM, Madhavarao CN.

Adv Exp Med Biol. 2006;576:145-63; discussion 361-3. Review. No abstract available. PMID: 16802710 [PubMed - indexed for MEDLINE]Related articles

Canavan disease: studies on the knockout mouse.

Matalon R, Michals-Matalon K, Surendran S, Tyring SK.

Adv Exp Med Biol. 2006;576:77-93; discussion 361-3. Review.PMID: 16802706 [PubMed - indexed for MEDLINE]Related articles

Characterization of human aspartoacylase: the brain enzyme responsible for Canavan disease.

Le Coq J, An HJ, Lebrilla C, Viola RE.

Biochemistry. 2006 May 9;45(18):5878-84.PMID: 16669630 [PubMed - indexed for MEDLINE]Related articlesFree article

Canavan disease and the role of N-acetylaspartate in myelin synthesis.

Namboodiri AM, Peethambaran A, Mathew R, Sambhu PA, Hershfield J, Moffett JR, Madhavarao CN.

Mol Cell Endocrinol. 2006 Jun 27;252(1-2):216-23. Epub 2006 May 2. Review.PMID: 16647192 [PubMed - indexed for MEDLINE]Related articles

Immune responses to AAV in a phase I study for Canavan disease.

McPhee SW, Janson CG, Li C, Samulski RJ, Camp AS, Francis J, Shera D, Lioutermann L, Feely M, Freese A, Leone P.

J Gene Med. 2006 May;8(5):577-88.PMID: 16532510 [PubMed - indexed for MEDLINE]Related articles