PubMed

Radioresistant cervical cancer shows upregulation of the NHEJ proteins DNA-PKcs, Ku70 and Ku86.

Beskow C, Skikuniene J, Holgersson A, Nilsson B, Lewensohn R, Kanter L, Viktorsson K.

Br J Cancer. 2009 Sep 1;101(5):816-21. Epub 2009 Aug 11.PMID: 19672258 [PubMed - indexed for MEDLINE]Related articles

Lung cancer susceptibility and prognosis associated with polymorphisms in the nonhomologous end-joining pathway genes: a multiple genotype-phenotype study.

Tseng RC, Hsieh FJ, Shih CM, Hsu HS, Chen CY, Wang YC.

Cancer. 2009 Jul 1;115(13):2939-48.PMID: 19408343 [PubMed - indexed for MEDLINE]Related articles

p53 acetylation is crucial for its transcription-independent proapoptotic functions.

Yamaguchi H, Woods NT, Piluso LG, Lee HH, Chen J, Bhalla KN, Monteiro A, Liu X, Hung MC, Wang HG.

J Biol Chem. 2009 Apr 24;284(17):11171-83. Epub 2009 Mar 5.PMID: 19265193 [PubMed - indexed for MEDLINE]Related articles

Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose and association with genetic polymorphisms in DNA DSB repair genes.

Werbrouck J, De Ruyck K, Duprez F, Veldeman L, Claes K, Van Eijkeren M, Boterberg T, Willems P, Vral A, De Neve W, Thierens H.

Int J Radiat Oncol Biol Phys. 2009 Mar 15;73(4):1187-95.PMID: 19251090 [PubMed - indexed for MEDLINE]Related articles

Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk.

Michiels S, Laplanche A, Boulet T, Dessen P, Guillonneau B, Méjean A, Desgrandchamps F, Lathrop M, Sarasin A, Benhamou S.

Carcinogenesis. 2009 May;30(5):763-8. Epub 2009 Feb 23.PMID: 19237606 [PubMed - indexed for MEDLINE]Related articles

A polymorphism in the promoter region of Ku70/XRCC6, associated with breast cancer risk and oestrogen exposure.

Willems P, De Ruyck K, Van den Broecke R, Makar A, Perletti G, Thierens H, Vral A.

J Cancer Res Clin Oncol. 2009 Sep;135(9):1159-68. Epub 2009 Feb 15.PMID: 19219618 [PubMed - indexed for MEDLINE]Related articles

Poly(ADP-ribose) Polymerase 1 Interacts with Nuclear Respiratory Factor 1 (NRF-1) and Plays a Role in NRF-1 Transcriptional Regulation.

Hossain MB, Ji P, Anish R, Jacobson RH, Takada S.

J Biol Chem. 2009 Mar 27;284(13):8621-32. Epub 2009 Jan 30.PMID: 19181665 [PubMed - indexed for MEDLINE]Related articles

Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression.

Pucci S, Mazzarelli P, Sesti F, Boothman DA, Spagnoli LG.

Cell Cycle. 2009 Feb 1;8(3):473-81. Epub 2009 Feb 18. Erratum in: Cell Cycle. 2009 Jul 15;8(14):2305. Paola, Mazzarelli [corrected to Mazzarelli, Paola]; Fabiola, Sesti [corrected to Sesti, Fabiola]; David, Boothman A [corrected to Boothman, David A]; Luigi, Spagnoli G [corrected to Spagnoli, Luigi G]. PMID: 19177010 [PubMed - indexed for MEDLINE]Related articles

Rickettsial outer-membrane protein B (rOmpB) mediates bacterial invasion through Ku70 in an actin, c-Cbl, clathrin and caveolin 2-dependent manner.

Chan YG, Cardwell MM, Hermanas TM, Uchiyama T, Martinez JJ.

Cell Microbiol. 2009 Apr;11(4):629-44. Epub 2009 Jan 7.PMID: 19134120 [PubMed - indexed for MEDLINE]Related articles

A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility.

Vineis P, Manuguerra M, Kavvoura FK, Guarrera S, Allione A, Rosa F, Di Gregorio A, Polidoro S, Saletta F, Ioannidis JP, Matullo G.

J Natl Cancer Inst. 2009 Jan 7;101(1):24-36. Epub 2008 Dec 30.PMID: 19116388 [PubMed - indexed for MEDLINE]Related articles

Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.

Enjuanes A, Benavente Y, Bosch F, Martín-Guerrero I, Colomer D, Pérez-Alvarez S, Reina O, Ardanaz MT, Jares P, García-Orad A, Pujana MA, Montserrat E, de Sanjosé S, Campo E.

Cancer Res. 2008 Dec 15;68(24):10178-86.PMID: 19074885 [PubMed - indexed for MEDLINE]Related articles

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.

Palmieri RT, Wilson MA, Iversen ES, Clyde MA, Calingaert B, Moorman PG, Poole C, Anderson AR, Anderson S, Anton-Culver H, Beesley J, Hogdall E, Brewster W, Carney ME, Chen X, Chenevix-Trench G, Chang-Claude J, Cunningham JM, Dicioccio RA, Doherty JA, Easton DF, Edlund CK, Gayther SA, Gentry-Maharaj A, Goode EL, Goodman MT, Kjaer SK, Hogdall CK, Hopkins MP, Jenison EL, Blaakaer J, Lurie G, McGuire V, Menon U, Moysich KB, Ness RB, Pearce CL, Pharoah PD, Pike MC, Ramus SJ, Rossing MA, Song H, Terada KY, Vandenberg D, Vierkant RA, Wang-Gohrke S, Webb PM, Whittemore AS, Wu AH, Ziogas A, Berchuck A, Schildkraut JM; Ovarian Cancer Association Consortium; Australian Cancer Study (Ovarian Cancer Group); Australian Ovarian Cancer Study Group.

Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3567-72.PMID: 19064572 [PubMed - indexed for MEDLINE]Related articles

Genotype-phenotype relationship between DNA repair gene genetic polymorphisms and DNA repair capacity.

Shin A, Lee KM, Ahn B, Park CG, Noh SK, Park DY, Ahn SH, Yoo KY, Kang D.

Asian Pac J Cancer Prev. 2008 Jul-Sep;9(3):501-5.PMID: 18990028 [PubMed - indexed for MEDLINE]Related articles

Expression of apolipoprotein C-IV is regulated by Ku antigen/peroxisome proliferator-activated receptor gamma complex and correlates with liver steatosis.

Kim E, Li K, Lieu C, Tong S, Kawai S, Fukutomi T, Zhou Y, Wands J, Li J.

J Hepatol. 2008 Nov;49(5):787-98. Epub 2008 Sep 7.PMID: 18809223 [PubMed - indexed for MEDLINE]Related articlesFree article

Single-nucleotide polymorphisms in DNA double-strand break repair genes: association with head and neck cancer and interaction with tobacco use and alcohol consumption.

Werbrouck J, De Ruyck K, Duprez F, Van Eijkeren M, Rietzschel E, Bekaert S, Vral A, De Neve W, Thierens H.

Mutat Res. 2008 Oct 30;656(1-2):74-81. Epub 2008 Aug 13.PMID: 18768166 [PubMed - indexed for MEDLINE]Related articles

Ku antigen interacts with abasic sites.

Ilina ES, Lavrik OI, Khodyreva SN.

Biochim Biophys Acta. 2008 Nov;1784(11):1777-85. Epub 2008 Aug 13.PMID: 18757043 [PubMed - indexed for MEDLINE]Related articles

Hypoxia downregulates Ku70/80 expression in cervical carcinoma tumors.

Lara PC, Lloret M, Clavo B, Apolinario RM, Bordón E, Rey A, Falcón O, Alonso AR, Belka C.

Radiother Oncol. 2008 Nov;89(2):222-6. Epub 2008 Aug 14.PMID: 18706726 [PubMed - indexed for MEDLINE]Related articles

Ku70 predicts response and primary tumor recurrence after therapy in locally advanced head and neck cancer.

Pavón MA, Parreño M, León X, Sancho FJ, Céspedes MV, Casanova I, Lopez-Pousa A, Mangues MA, Quer M, Barnadas A, Mangues R.

Int J Cancer. 2008 Sep 1;123(5):1068-79.PMID: 18546291 [PubMed - indexed for MEDLINE]Related articles

Oral cancer and genetic polymorphism of DNA double strand break gene Ku70 in Taiwan.

Bau DT, Tseng HC, Wang CH, Chiu CF, Hua CH, Wu CN, Liang SY, Wang CL, Tsai CW, Tsai MH.

Oral Oncol. 2008 Nov;44(11):1047-51. Epub 2008 May 19.PMID: 18487076 [PubMed - in process]Related articles

Influence of multiple genetic polymorphisms on genitourinary morbidity after carbon ion radiotherapy for prostate cancer.

Suga T, Iwakawa M, Tsuji H, Ishikawa H, Oda E, Noda S, Otsuka Y, Ishikawa A, Ishikawa K, Shimazaki J, Mizoe JE, Tsujii H, Imai T.

Int J Radiat Oncol Biol Phys. 2008 Nov 1;72(3):808-13. Epub 2008 Apr 18.PMID: 18374504 [PubMed - indexed for MEDLINE]Related articles