PubMed

BRCA2: Shining light on the regulation of DNA-binding selectivity by RAD51.

Carreira A, Kowalczykowski SC.

Cell Cycle. 2009 Nov 1;8(21):3445-7. Epub 2009 Nov 6. No abstract available. PMID: 19838057 [PubMed - in process]Related articlesFree article

Second-end DNA capture in double-strand break repair: how to catch a DNA by its tail.

Nimonkar AV, Kowalczykowski SC.

Cell Cycle. 2009 Jun 15;8(12):1816-7. Epub 2009 Jun 6. No abstract available. PMID: 19471119 [PubMed - indexed for MEDLINE]Related articlesFree article

Reconstitution of initial steps of dsDNA break repair by the RecF pathway of E. coli.

Handa N, Morimatsu K, Lovett ST, Kowalczykowski SC.

Genes Dev. 2009 May 15;23(10):1234-45.PMID: 19451222 [PubMed - indexed for MEDLINE]Related articlesFree article

Single molecule analysis of a red fluorescent RecA protein reveals a defect in nucleoprotein filament nucleation that relates to its reduced biological functions.

Handa N, Amitani I, Gumlaw N, Sandler SJ, Kowalczykowski SC.

J Biol Chem. 2009 Jul 10;284(28):18664-73. Epub 2009 May 5.PMID: 19419960 [PubMed - indexed for MEDLINE]Related articles

The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51.

Carreira A, Hilario J, Amitani I, Baskin RJ, Shivji MK, Venkitaraman AR, Kowalczykowski SC.

Cell. 2009 Mar 20;136(6):1032-43.PMID: 19303847 [PubMed - indexed for MEDLINE]Related articles

An archaeal Rad54 protein remodels DNA and stimulates DNA strand exchange by RadA.

Haseltine CA, Kowalczykowski SC.

Nucleic Acids Res. 2009 May;37(8):2757-70. Epub 2009 Mar 12.PMID: 19282450 [PubMed - indexed for MEDLINE]Related articlesFree article

Rad52 promotes second-end DNA capture in double-stranded break repair to form complement-stabilized joint molecules.

Nimonkar AV, Sica RA, Kowalczykowski SC.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3077-82. Epub 2009 Feb 9.PMID: 19204284 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules.

Hilario J, Amitani I, Baskin RJ, Kowalczykowski SC.

Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):361-8. Epub 2009 Jan 2.PMID: 19122145 [PubMed - indexed for MEDLINE]Related articlesFree article

RecBCD enzyme and the repair of double-stranded DNA breaks.

Dillingham MS, Kowalczykowski SC.

Microbiol Mol Biol Rev. 2008 Dec;72(4):642-71, Table of Contents. Review.PMID: 19052323 [PubMed - indexed for MEDLINE]Related articles

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair.

Nimonkar AV, Ozsoy AZ, Genschel J, Modrich P, Kowalczykowski SC.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16906-11. Epub 2008 Oct 29.PMID: 18971343 [PubMed - indexed for MEDLINE]Related articlesFree article

Fluorescent single-stranded DNA binding protein as a probe for sensitive, real-time assays of helicase activity.

Dillingham MS, Tibbles KL, Hunter JL, Bell JC, Kowalczykowski SC, Webb MR.

Biophys J. 2008 Oct;95(7):3330-9. Epub 2008 Jul 3.PMID: 18599625 [PubMed - indexed for MEDLINE]Related articlesFree article

Structural biology: snapshots of DNA repair.

Kowalczykowski SC.

Nature. 2008 May 22;453(7194):463-6. No abstract available. PMID: 18497811 [PubMed - indexed for MEDLINE]Related articles

Rad51 protein controls Rad52-mediated DNA annealing.

Wu Y, Kantake N, Sugiyama T, Kowalczykowski SC.

J Biol Chem. 2008 May 23;283(21):14883-92. Epub 2008 Mar 12.PMID: 18337252 [PubMed - indexed for MEDLINE]Related articlesFree article

RecBCD enzyme switches lead motor subunits in response to chi recognition.

Spies M, Amitani I, Baskin RJ, Kowalczykowski SC.

Cell. 2007 Nov 16;131(4):694-705.PMID: 18022364 [PubMed - indexed for MEDLINE]Related articlesFree article

Single molecule imaging of Tid1/Rdh54, a Rad54 homolog that translocates on duplex DNA and can disrupt joint molecules.

Nimonkar AV, Amitani I, Baskin RJ, Kowalczykowski SC.

J Biol Chem. 2007 Oct 19;282(42):30776-84. Epub 2007 Aug 16.PMID: 17704061 [PubMed - indexed for MEDLINE]Related articlesFree article

RecA.

Galletto R, Kowalczykowski SC.

Curr Biol. 2007 Jun 5;17(11):R395-7. No abstract available. PMID: 17550759 [PubMed - indexed for MEDLINE]Related articles

A RecA mutant, RecA(730), suppresses the recombination deficiency of the RecBC(1004)D-chi* interaction in vitro and in vivo.

Handa N, Kowalczykowski SC.

J Mol Biol. 2007 Feb 2;365(5):1314-25. Epub 2006 Nov 1.PMID: 17141804 [PubMed - indexed for MEDLINE]Related articlesFree article

Rad52-mediated DNA annealing after Rad51-mediated DNA strand exchange promotes second ssDNA capture.

Sugiyama T, Kantake N, Wu Y, Kowalczykowski SC.

EMBO J. 2006 Nov 29;25(23):5539-48. Epub 2006 Nov 9.PMID: 17093500 [PubMed - indexed for MEDLINE]Related articlesFree article

The DNA binding preference of RAD52 and RAD59 proteins: implications for RAD52 and RAD59 protein function in homologous recombination.

Wu Y, Siino JS, Sugiyama T, Kowalczykowski SC.

J Biol Chem. 2006 Dec 29;281(52):40001-9. Epub 2006 Oct 12.PMID: 17040915 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct observation of individual RecA filaments assembling on single DNA molecules.

Galletto R, Amitani I, Baskin RJ, Kowalczykowski SC.

Nature. 2006 Oct 19;443(7113):875-8. Epub 2006 Sep 20.PMID: 16988658 [PubMed - indexed for MEDLINE]Related articles

Visualization of Rad54, a chromatin remodeling protein, translocating on single DNA molecules.

Amitani I, Baskin RJ, Kowalczykowski SC.

Mol Cell. 2006 Jul 7;23(1):143-8.PMID: 16818238 [PubMed - indexed for MEDLINE]Related articles

Human Rad51 protein displays enhanced homologous pairing of DNA sequences resembling those at genetically unstable loci.

Seitz EM, Kowalczykowski SC.

Nucleic Acids Res. 2006 May 24;34(10):2847-52. Print 2006.PMID: 16723430 [PubMed - indexed for MEDLINE]Related articlesFree article

The AddAB helicase/nuclease forms a stable complex with its cognate chi sequence during translocation.

Chédin F, Handa N, Dillingham MS, Kowalczykowski SC.

J Biol Chem. 2006 Jul 7;281(27):18610-7. Epub 2006 Apr 21.PMID: 16632468 [PubMed - indexed for MEDLINE]Related articlesFree article

DNA annealing mediated by Rad52 and Rad59 proteins.

Wu Y, Sugiyama T, Kowalczykowski SC.

J Biol Chem. 2006 Jun 2;281(22):15441-9. Epub 2006 Mar 25.PMID: 16565518 [PubMed - indexed for MEDLINE]Related articlesFree article

The RecA binding locus of RecBCD is a general domain for recruitment of DNA strand exchange proteins.

Spies M, Kowalczykowski SC.

Mol Cell. 2006 Feb 17;21(4):573-80.PMID: 16483938 [PubMed - indexed for MEDLINE]Related articles

Bipolar DNA translocation contributes to highly processive DNA unwinding by RecBCD enzyme.

Dillingham MS, Webb MR, Kowalczykowski SC.

J Biol Chem. 2005 Nov 4;280(44):37069-77. Epub 2005 Jul 22.PMID: 16041061 [PubMed - indexed for MEDLINE]Related articlesFree article

Translocation by the RecB motor is an absolute requirement for {chi}-recognition and RecA protein loading by RecBCD enzyme.

Spies M, Dillingham MS, Kowalczykowski SC.

J Biol Chem. 2005 Nov 4;280(44):37078-87. Epub 2005 Jul 22.PMID: 16041060 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54.

Thomä NH, Czyzewski BK, Alexeev AA, Mazin AV, Kowalczykowski SC, Pavletich NP.

Nat Struct Mol Biol. 2005 Apr;12(4):350-6. Epub 2005 Apr 3.PMID: 15806108 [PubMed - indexed for MEDLINE]Related articles

Direct visualization of RecBCD movement reveals cotranslocation of the RecD motor after chi recognition.

Handa N, Bianco PR, Baskin RJ, Kowalczykowski SC.

Mol Cell. 2005 Mar 4;17(5):745-50.PMID: 15749023 [PubMed - indexed for MEDLINE]Related articles

Cancer: catalyst of a catalyst.

Kowalczykowski SC.

Nature. 2005 Feb 10;433(7026):591-2. No abstract available. PMID: 15703734 [PubMed - indexed for MEDLINE]Related articles

Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks.

Singleton MR, Dillingham MS, Gaudier M, Kowalczykowski SC, Wigley DB.

Nature. 2004 Nov 11;432(7014):187-93.PMID: 15538360 [PubMed - indexed for MEDLINE]Related articles

Saccharomyces cerevisiae Mer3 helicase stimulates 3'-5' heteroduplex extension by Rad51; implications for crossover control in meiotic recombination.

Mazina OM, Mazin AV, Nakagawa T, Kolodner RD, Kowalczykowski SC.

Cell. 2004 Apr 2;117(1):47-56.PMID: 15066281 [PubMed - indexed for MEDLINE]Related articles

A molecular throttle: the recombination hotspot chi controls DNA translocation by the RecBCD helicase.

Spies M, Bianco PR, Dillingham MS, Handa N, Baskin RJ, Kowalczykowski SC.

Cell. 2003 Sep 5;114(5):647-54.PMID: 13678587 [PubMed - indexed for MEDLINE]Related articles

RecQ helicase stimulates both DNA catenation and changes in DNA topology by topoisomerase III.

Harmon FG, Brockman JP, Kowalczykowski SC.

J Biol Chem. 2003 Oct 24;278(43):42668-78. Epub 2003 Aug 8.PMID: 12909639 [PubMed - indexed for MEDLINE]Related articlesFree article

RecBCD enzyme is a bipolar DNA helicase.

Dillingham MS, Spies M, Kowalczykowski SC.

Nature. 2003 Jun 19;423(6942):893-7.PMID: 12815438 [PubMed - indexed for MEDLINE]Related articles

RecFOR proteins load RecA protein onto gapped DNA to accelerate DNA strand exchange: a universal step of recombinational repair.

Morimatsu K, Kowalczykowski SC.

Mol Cell. 2003 May;11(5):1337-47.PMID: 12769856 [PubMed - indexed for MEDLINE]Related articles

The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments.

Veaute X, Jeusset J, Soustelle C, Kowalczykowski SC, Le Cam E, Fabre F.

Nature. 2003 May 15;423(6937):309-12.PMID: 12748645 [PubMed - indexed for MEDLINE]Related articles

Biochemical characterization of a mutant RecA protein altered in DNA-binding loop 1.

Mirshad JK, Kowalczykowski SC.

Biochemistry. 2003 May 20;42(19):5945-54.PMID: 12741853 [PubMed - indexed for MEDLINE]Related articles

Biochemical basis of the constitutive coprotease activity of RecA P67W protein.

Mirshad JK, Kowalczykowski SC.

Biochemistry. 2003 May 20;42(19):5937-44.PMID: 12741852 [PubMed - indexed for MEDLINE]Related articles

The recombination-deficient mutant RPA (rfa1-t11) is displaced slowly from single-stranded DNA by Rad51 protein.

Kantake N, Sugiyama T, Kolodner RD, Kowalczykowski SC.

J Biol Chem. 2003 Jun 27;278(26):23410-7. Epub 2003 Apr 14.PMID: 12697761 [PubMed - indexed for MEDLINE]Related articlesFree article

Rad54 protein possesses chromatin-remodeling activity stimulated by the Rad51-ssDNA nucleoprotein filament.

Alexeev A, Mazin A, Kowalczykowski SC.

Nat Struct Biol. 2003 Mar;10(3):182-6.PMID: 12577053 [PubMed - indexed for MEDLINE]Related articles

A novel function of Rad54 protein. Stabilization of the Rad51 nucleoprotein filament.

Mazin AV, Alexeev AA, Kowalczykowski SC.

J Biol Chem. 2003 Apr 18;278(16):14029-36. Epub 2003 Feb 3.PMID: 12566442 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular mimicry connects BRCA2 to Rad51 and recombinational DNA repair.

Kowalczykowski SC.

Nat Struct Biol. 2002 Dec;9(12):897-9. No abstract available. PMID: 12447354 [PubMed - indexed for MEDLINE]Related articles

Escherichia coli RecO protein anneals ssDNA complexed with its cognate ssDNA-binding protein: A common step in genetic recombination.

Kantake N, Madiraju MV, Sugiyama T, Kowalczykowski SC.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15327-32. Epub 2002 Nov 18.PMID: 12438681 [PubMed - indexed for MEDLINE]Related articlesFree article

Complex formation by the human Rad51B and Rad51C DNA repair proteins and their activities in vitro.

Lio YC, Mazin AV, Kowalczykowski SC, Chen DJ.

J Biol Chem. 2003 Jan 24;278(4):2469-78. Epub 2002 Nov 8.PMID: 12427746 [PubMed - indexed for MEDLINE]Related articlesFree article

Escherichia coli RecX inhibits RecA recombinase and coprotease activities in vitro and in vivo.

Stohl EA, Brockman JP, Burkle KL, Morimatsu K, Kowalczykowski SC, Seifert HS.

J Biol Chem. 2003 Jan 24;278(4):2278-85. Epub 2002 Nov 9.PMID: 12427742 [PubMed - indexed for MEDLINE]Related articlesFree article

Rad52 protein associates with replication protein A (RPA)-single-stranded DNA to accelerate Rad51-mediated displacement of RPA and presynaptic complex formation.

Sugiyama T, Kowalczykowski SC.

J Biol Chem. 2002 Aug 30;277(35):31663-72. Epub 2002 Jun 19.PMID: 12077133 [PubMed - indexed for MEDLINE]Related articlesFree article

Rad52 protein has a second stimulatory role in DNA strand exchange that complements replication protein-A function.

New JH, Kowalczykowski SC.

J Biol Chem. 2002 Jul 19;277(29):26171-6. Epub 2002 May 9.PMID: 12004070 [PubMed - indexed for MEDLINE]Related articlesFree article

A distinctive single-strand DNA-binding protein from the Archaeon Sulfolobus solfataricus.

Haseltine CA, Kowalczykowski SC.

Mol Microbiol. 2002 Mar;43(6):1505-15.PMID: 11971263 [PubMed - indexed for MEDLINE]Related articles

A novel family of regulated helicases/nucleases from Gram-positive bacteria: insights into the initiation of DNA recombination.

Chédin F, Kowalczykowski SC.

Mol Microbiol. 2002 Feb;43(4):823-34. Review. No abstract available. PMID: 11929535 [PubMed - indexed for MEDLINE]Related articles