PubMed

Effect of retinoic acid signaling on Wnt/beta-catenin and FGF signaling during body axis extension.

Zhao X, Duester G.

Gene Expr Patterns. 2009 Sep;9(6):430-5. Epub 2009 Jun 17.PMID: 19539783 [PubMed - in process]Related articles

Retinoic acid promotes limb induction through effects on body axis extension but is unnecessary for limb patterning.

Zhao X, Sirbu IO, Mic FA, Molotkova N, Molotkov A, Kumar S, Duester G.

Curr Biol. 2009 Jun 23;19(12):1050-7. Epub 2009 May 21.PMID: 19464179 [PubMed - indexed for MEDLINE]Related articles

Enzymology and molecular biology of carbonyl metabolism. Introduction.

Weiner H, Duester G, Maser E, Plapp B.

Chem Biol Interact. 2009 Mar 16;178(1-3):1. Epub 2008 Nov 14. No abstract available. PMID: 19056364 [PubMed - indexed for MEDLINE]Related articles

Medium- and short-chain dehydrogenase/reductase gene and protein families : Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism.

Parés X, Farrés J, Kedishvili N, Duester G.

Cell Mol Life Sci. 2008 Dec;65(24):3936-49. Review.PMID: 19011747 [PubMed - indexed for MEDLINE]Related articlesFree article

Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems.

Levi BP, Yilmaz OH, Duester G, Morrison SJ.

Blood. 2009 Feb 19;113(8):1670-80. Epub 2008 Oct 29.PMID: 18971422 [PubMed - indexed for MEDLINE]Related articlesFree article

Keeping an eye on retinoic acid signaling during eye development.

Duester G.

Chem Biol Interact. 2009 Mar 16;178(1-3):178-81. Epub 2008 Sep 11.PMID: 18831967 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoic acid synthesis and signaling during early organogenesis.

Duester G.

Cell. 2008 Sep 19;134(6):921-31. Review.PMID: 18805086 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue expression pattern of class II and class V genes found in the Adh complex on mouse chromosome 3.

Szalai G, Veres M, Duester G, Lawther R, Lockhart M, Felder MR.

Biochem Genet. 2008 Dec;46(11-12):685-95. Epub 2008 Sep 19.PMID: 18802746 [PubMed - indexed for MEDLINE]Related articles

Retinoic acid controls heart anteroposterior patterning by down-regulating Isl1 through the Fgf8 pathway.

Sirbu IO, Zhao X, Duester G.

Dev Dyn. 2008 Jun;237(6):1627-35.PMID: 18498088 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoic acid regulation of the somitogenesis clock.

Duester G.

Birth Defects Res C Embryo Today. 2007 Jun;81(2):84-92. Review.PMID: 17600781 [PubMed - indexed for MEDLINE]Related articlesFree article

Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice.

Lassen N, Bateman JB, Estey T, Kuszak JR, Nees DW, Piatigorsky J, Duester G, Day BJ, Huang J, Hines LM, Vasiliou V.

J Biol Chem. 2007 Aug 31;282(35):25668-76. Epub 2007 Jun 13.PMID: 17567582 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinaldehyde represses adipogenesis and diet-induced obesity.

Ziouzenkova O, Orasanu G, Sharlach M, Akiyama TE, Berger JP, Viereck J, Hamilton JA, Tang G, Dolnikowski GG, Vogel S, Duester G, Plutzky J.

Nat Med. 2007 Jun;13(6):695-702. Epub 2007 May 27.PMID: 17529981 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of retinoic acid during forebrain development begins late when Raldh3 generates retinoic acid in the ventral subventricular zone.

Molotkova N, Molotkov A, Duester G.

Dev Biol. 2007 Mar 15;303(2):601-10. Epub 2006 Dec 2.PMID: 17207476 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (retinaldehyde dehydrogenase 1).

Collard F, Vertommen D, Fortpied J, Duester G, Van Schaftingen E.

Biochimie. 2007 Mar;89(3):369-73. Epub 2006 Nov 24.PMID: 17175089 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning.

Molotkov A, Molotkova N, Duester G.

Development. 2006 May;133(10):1901-10. Epub 2006 Apr 12.PMID: 16611695 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoic-acid signalling in node ectoderm and posterior neural plate directs left-right patterning of somitic mesoderm.

Sirbu IO, Duester G.

Nat Cell Biol. 2006 Mar;8(3):271-7. Epub 2006 Feb 19.PMID: 16489341 [PubMed - indexed for MEDLINE]Related articles

In vivo contribution of Class III alcohol dehydrogenase (ADH3) to alcohol metabolism through activation by cytoplasmic solution hydrophobicity.

Haseba T, Duester G, Shimizu A, Yamamoto I, Kameyama K, Ohno Y.

Biochim Biophys Acta. 2006 Mar;1762(3):276-83. Epub 2006 Jan 4.PMID: 16431092 [PubMed - indexed for MEDLINE]Related articles

Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome.

Guris DL, Duester G, Papaioannou VE, Imamoto A.

Dev Cell. 2006 Jan;10(1):81-92.PMID: 16399080 [PubMed - indexed for MEDLINE]Related articles

Omega-oxidation of 20-hydroxyeicosatetraenoic acid (20-HETE) in cerebral microvascular smooth muscle and endothelium by alcohol dehydrogenase 4.

Collins XH, Harmon SD, Kaduce TL, Berst KB, Fang X, Moore SA, Raju TV, Falck JR, Weintraub NL, Duester G, Plapp BV, Spector AA.

J Biol Chem. 2005 Sep 30;280(39):33157-64. Epub 2005 Aug 4.PMID: 16081420 [PubMed - indexed for MEDLINE]Related articlesFree article

Shifting boundaries of retinoic acid activity control hindbrain segmental gene expression.

Sirbu IO, Gresh L, Barra J, Duester G.

Development. 2005 Jun;132(11):2611-22. Epub 2005 May 4.PMID: 15872003 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development.

Molotkov A, Molotkova N, Duester G.

Dev Dyn. 2005 Apr;232(4):950-7.PMID: 15739227 [PubMed - indexed for MEDLINE]Related articlesFree article

Requirement of mesodermal retinoic acid generated by Raldh2 for posterior neural transformation.

Molotkova N, Molotkov A, Sirbu IO, Duester G.

Mech Dev. 2005 Feb;122(2):145-55.PMID: 15652703 [PubMed - indexed for MEDLINE]Related articles

Raldh2 expression in optic vesicle generates a retinoic acid signal needed for invagination of retina during optic cup formation.

Mic FA, Molotkov A, Molotkova N, Duester G.

Dev Dyn. 2004 Oct;231(2):270-7.PMID: 15366004 [PubMed - indexed for MEDLINE]Related articlesFree article

Opposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradation.

Molotkov A, Ghyselinck NB, Chambon P, Duester G.

Biochem J. 2004 Oct 15;383(Pt 2):295-302.PMID: 15193143 [PubMed - indexed for MEDLINE]Related articlesFree article

The specificity of alcohol dehydrogenase with cis-retinoids. Activity with 11-cis-retinol and localization in retina.

Martras S, Alvarez R, Martínez SE, Torres D, Gallego O, Duester G, Farrés J, de Lera AR, Parés X.

Eur J Biochem. 2004 May;271(9):1660-70.PMID: 15096205 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoic acid synthesis controlled by Raldh2 is required early for limb bud initiation and then later as a proximodistal signal during apical ectodermal ridge formation.

Mic FA, Sirbu IO, Duester G.

J Biol Chem. 2004 Jun 18;279(25):26698-706. Epub 2004 Apr 6.PMID: 15069081 [PubMed - indexed for MEDLINE]Related articlesFree article

Patterning of forelimb bud myogenic precursor cells requires retinoic acid signaling initiated by Raldh2.

Mic FA, Duester G.

Dev Biol. 2003 Dec 1;264(1):191-201.PMID: 14623241 [PubMed - indexed for MEDLINE]Related articles

Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid.

Molotkov A, Duester G.

J Biol Chem. 2003 Sep 19;278(38):36085-90. Epub 2003 Jul 7.PMID: 12851412 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retina.

Fan X, Molotkov A, Manabe S, Donmoyer CM, Deltour L, Foglio MH, Cuenca AE, Blaner WS, Lipton SA, Duester G.

Mol Cell Biol. 2003 Jul;23(13):4637-48.PMID: 12808103 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression, localization and potential physiological significance of alcohol dehydrogenase in the gastrointestinal tract.

Vaglenova J, Martínez SE, Porté S, Duester G, Farrés J, Parés X.

Eur J Biochem. 2003 Jun;270(12):2652-62.PMID: 12787032 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoid activation of retinoic acid receptor but not retinoid X receptor is sufficient to rescue lethal defect in retinoic acid synthesis.

Mic FA, Molotkov A, Benbrook DM, Duester G.

Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7135-40. Epub 2003 Jun 2.PMID: 12782789 [PubMed - indexed for MEDLINE]Related articlesFree article

Enzymatic characterization of recombinant mouse retinal dehydrogenase type 1.

Gagnon I, Duester G, Bhat PV.

Biochem Pharmacol. 2003 May 15;65(10):1685-90.PMID: 12754104 [PubMed - indexed for MEDLINE]Related articles

Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain.

Galter D, Carmine A, Buervenich S, Duester G, Olson L.

Eur J Biochem. 2003 Mar;270(6):1316-26.PMID: 12631290 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid.

Duester G, Mic FA, Molotkov A.

Chem Biol Interact. 2003 Feb 1;143-144:201-10. Review.PMID: 12604205 [PubMed - indexed for MEDLINE]Related articles

Retinoic acid synthesis in the prevertebrate amphioxus involves retinol oxidation.

Dalfó D, Albalat R, Molotkov A, Duester G, Gonzàlez-Duarte R.

Dev Genes Evol. 2002 Sep;212(8):388-93. Epub 2002 Jul 13.PMID: 12203095 [PubMed - indexed for MEDLINE]Related articles

Distal and proximal cis-linked sequences are needed for the total expression phenotype of the mouse alcohol dehydrogenase 1 (Adh1) gene.

Szalai G, Xie D, Wassenich M, Veres M, Ceci JD, Dewey MJ, Molotkov A, Duester G, Felder MR.

Gene. 2002 May 29;291(1-2):259-70.PMID: 12095699 [PubMed - indexed for MEDLINE]Related articles

Excessive vitamin A toxicity in mice genetically deficient in either alcohol dehydrogenase Adh1 or Adh3.

Molotkov A, Fan X, Duester G.

Eur J Biochem. 2002 May;269(10):2607-12.PMID: 12027900 [PubMed - indexed for MEDLINE]Related articlesFree article

Kinetic mechanism of human class IV alcohol dehydrogenase functioning as retinol dehydrogenase.

Chou CF, Lai CL, Chang YC, Duester G, Yin SJ.

J Biol Chem. 2002 Jul 12;277(28):25209-16. Epub 2002 May 7. Erratum in: J Biol Chem 2002 Oct 25;277(43):41294. PMID: 11997393 [PubMed - indexed for MEDLINE]Related articlesFree article

Kinetic analysis of mouse retinal dehydrogenase type-2 (RALDH2) for retinal substrates.

Gagnon I, Duester G, Bhat PV.

Biochim Biophys Acta. 2002 Apr 1;1596(1):156-62.PMID: 11983430 [PubMed - indexed for MEDLINE]Related articles

Retinol/ethanol drug interaction during acute alcohol intoxication in mice involves inhibition of retinol metabolism to retinoic acid by alcohol dehydrogenase.

Molotkov A, Duester G.

J Biol Chem. 2002 Jun 21;277(25):22553-7. Epub 2002 Apr 17.PMID: 11960985 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3.

Molotkov A, Fan X, Deltour L, Foglio MH, Martras S, Farrés J, Parés X, Duester G.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5337-42.PMID: 11959987 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice.

Mic FA, Haselbeck RJ, Cuenca AE, Duester G.

Development. 2002 May;129(9):2271-82.PMID: 11959834 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice.

Molotkov A, Deltour L, Foglio MH, Cuenca AE, Duester G.

J Biol Chem. 2002 Apr 19;277(16):13804-11. Epub 2002 Feb 8.PMID: 11836246 [PubMed - indexed for MEDLINE]Related articlesFree article

Organization of six functional mouse alcohol dehydrogenase genes on two overlapping bacterial artificial chromosomes.

Szalai G, Duester G, Friedman R, Jia H, Lin S, Roe BA, Felder MR.

Eur J Biochem. 2002 Jan;269(1):224-32.PMID: 11784316 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular analysis of genetic differences among inbred mouse strains controlling tissue expression pattern of alcohol dehydrogenase 4.

Dolney DE, Szalai G, Duester G, Felder MR.

Gene. 2001 Apr 18;267(2):145-56.PMID: 11313141 [PubMed - indexed for MEDLINE]Related articles

Genetic dissection of retinoid dehydrogenases.

Duester G.

Chem Biol Interact. 2001 Jan 30;130-132(1-3):469-80. Review.PMID: 11306068 [PubMed - indexed for MEDLINE]Related articles

RALDH3, a retinaldehyde dehydrogenase that generates retinoic acid, is expressed in the ventral retina, otic vesicle and olfactory pit during mouse development.

Mic FA, Molotkov A, Fan X, Cuenca AE, Duester G.

Mech Dev. 2000 Oct;97(1-2):227-30.PMID: 11025231 [PubMed - indexed for MEDLINE]Related articles

Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid.

Duester G.

Eur J Biochem. 2000 Jul;267(14):4315-24. Review.PMID: 10880953 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct functions for Aldh1 and Raldh2 in the control of ligand production for embryonic retinoid signaling pathways.

Haselbeck RJ, Hoffmann I, Duester G.

Dev Genet. 1999;25(4):353-64.PMID: 10570467 [PubMed - indexed for MEDLINE]Related articles

Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family.

Duester G, Farrés J, Felder MR, Holmes RS, Höög JO, Parés X, Plapp BV, Yin SJ, Jörnvall H.

Biochem Pharmacol. 1999 Aug 1;58(3):389-95.PMID: 10424757 [PubMed - indexed for MEDLINE]Related articles