PubMed

Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.

Bertrand MJ, Doiron K, Labbé K, Korneluk RG, Barker PA, Saleh M.

Immunity. 2009 Jun 19;30(6):789-801. Epub 2009 May 21.PMID: 19464198 [PubMed - indexed for MEDLINE]Related articles

Excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism.

Lebrun-Julien F, Duplan L, Pernet V, Osswald I, Sapieha P, Bourgeois P, Dickson K, Bowie D, Barker PA, Di Polo A.

J Neurosci. 2009 Apr 29;29(17):5536-45.PMID: 19403821 [PubMed - indexed for MEDLINE]Related articlesFree article

A p75(NTR) pivoting paradigm propels perspicacity.

Barker PA.

Neuron. 2009 Apr 16;62(1):3-5.PMID: 19376060 [PubMed - indexed for MEDLINE]Related articles

Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via brain-derived neurotrophic factor signaling.

Snapyan M, Lemasson M, Brill MS, Blais M, Massouh M, Ninkovic J, Gravel C, Berthod F, Götz M, Barker PA, Parent A, Saghatelyan A.

J Neurosci. 2009 Apr 1;29(13):4172-88.PMID: 19339612 [PubMed - indexed for MEDLINE]Related articlesFree article

Nuclear factor kappa B signaling regulates neuronal morphology and cocaine reward.

Russo SJ, Wilkinson MB, Mazei-Robison MS, Dietz DM, Maze I, Krishnan V, Renthal W, Graham A, Birnbaum SG, Green TA, Robison B, Lesselyong A, Perrotti LI, Bolaños CA, Kumar A, Clark MS, Neumaier JF, Neve RL, Bhakar AL, Barker PA, Nestler EJ.

J Neurosci. 2009 Mar 18;29(11):3529-37.PMID: 19295158 [PubMed - indexed for MEDLINE]Related articlesFree article

Whither proBDNF?

Barker PA.

Nat Neurosci. 2009 Feb;12(2):105-6. Review. No abstract available. PMID: 19172162 [PubMed - indexed for MEDLINE]Related articles

Observations on the function of nuclear factor kappa B (NF-kappaB) in the survival of adult primary sensory neurons after nerve injury.

Gushchina S, Leinster V, Wu D, Jasim A, Demestre M, Lopez de Heredia L, Michael GJ, Barker PA, Richardson PM, Magoulas C.

Mol Cell Neurosci. 2009 Feb;40(2):207-16. Epub 2008 Nov 8.PMID: 19049877 [PubMed - indexed for MEDLINE]Related articles

Mutations in the calcium-related gene IL1RAPL1 are associated with autism.

Piton A, Michaud JL, Peng H, Aradhya S, Gauthier J, Mottron L, Champagne N, Lafrenière RG, Hamdan FF; S2D team, Joober R, Fombonne E, Marineau C, Cossette P, Dubé MP, Haghighi P, Drapeau P, Barker PA, Carbonetto S, Rouleau GA.

Hum Mol Genet. 2008 Dec 15;17(24):3965-74. Epub 2008 Sep 18.PMID: 18801879 [PubMed - indexed for MEDLINE]Related articles

NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo.

Bertrand MJ, Kenchappa RS, Andrieu D, Leclercq-Smekens M, Nguyen HN, Carter BD, Muscatelli F, Barker PA, De Backer O.

Cell Death Differ. 2008 Dec;15(12):1921-9. Epub 2008 Sep 5.PMID: 18772898 [PubMed - indexed for MEDLINE]Related articlesFree article

Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development.

Pispa J, Pummila M, Barker PA, Thesleff I, Mikkola ML.

Hum Mol Genet. 2008 Nov 1;17(21):3380-91. Epub 2008 Aug 9.PMID: 18689798 [PubMed - indexed for MEDLINE]Related articlesFree article

Apoptotic sensitivity of murine IAP-deficient cells.

Rumble JM, Bertrand MJ, Csomos RA, Wright CW, Albert L, Mak TW, Barker PA, Duckett CS.

Biochem J. 2008 Oct 1;415(1):21-5.PMID: 18684108 [PubMed - indexed for MEDLINE]Related articlesFree article

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination.

Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J, Gillard JW, Jaquith JB, Morris SJ, Barker PA.

Mol Cell. 2008 Jun 20;30(6):689-700.PMID: 18570872 [PubMed - indexed for MEDLINE]Related articles

Soluble adenylyl cyclase is not required for axon guidance to netrin-1.

Moore SW, Lai Wing Sun K, Xie F, Barker PA, Conti M, Kennedy TE.

J Neurosci. 2008 Apr 9;28(15):3920-4.PMID: 18400890 [PubMed - indexed for MEDLINE]Related articlesFree article

Proneurotrophins require endocytosis and intracellular proteolysis to induce TrkA activation.

Boutilier J, Ceni C, Pagdala PC, Forgie A, Neet KE, Barker PA.

J Biol Chem. 2008 May 9;283(19):12709-16. Epub 2008 Feb 25.PMID: 18299325 [PubMed - indexed for MEDLINE]Related articlesFree article

Photic injury promotes cleavage of p75NTR by TACE and nuclear trafficking of the p75 intracellular domain.

Srinivasan B, Wang Z, Brun-Zinkernagel AM, Collier RJ, Black RA, Frank SJ, Barker PA, Roque RS.

Mol Cell Neurosci. 2007 Dec;36(4):449-61. Epub 2007 Aug 15.PMID: 17904861 [PubMed - indexed for MEDLINE]Related articles

Atmospheric science. The monsoon's past.

Barker PA.

Science. 2007 Jun 1;316(5829):1295-6. No abstract available. PMID: 17540892 [PubMed]Related articles

Something old, something new: BDNF-induced neuron survival requires TRPC channel function.

Sossin WS, Barker PA.

Nat Neurosci. 2007 May;10(5):537-8. No abstract available. PMID: 17453053 [PubMed - indexed for MEDLINE]Related articles

Stabilization of p73 by nuclear IkappaB kinase-alpha mediates cisplatin-induced apoptosis.

Furuya K, Ozaki T, Hanamoto T, Hosoda M, Hayashi S, Barker PA, Takano K, Matsumoto M, Nakagawara A.

J Biol Chem. 2007 Jun 22;282(25):18365-78. Epub 2007 Apr 23.PMID: 17452332 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypo-osmolar stress induces p75NTR expression by activating Sp1-dependent transcription.

Ramos A, Ho WC, Forte S, Dickson K, Boutilier J, Favell K, Barker PA.

J Neurosci. 2007 Feb 7;27(6):1498-506.PMID: 17287525 [PubMed - indexed for MEDLINE]Related articlesFree article

High affinity not in the vicinity?

Barker PA.

Neuron. 2007 Jan 4;53(1):1-4. Review.PMID: 17196523 [PubMed - indexed for MEDLINE]Related articles

The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface.

Sirerol-Piquer MS, Ayerdi-Izquierdo A, Morante-Redolat JM, Herranz-Pérez V, Favell K, Barker PA, Pérez-Tur J.

Hum Mol Genet. 2006 Dec 1;15(23):3436-45. Epub 2006 Oct 26.PMID: 17067999 [PubMed - indexed for MEDLINE]Related articlesFree article

Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons.

Kenchappa RS, Zampieri N, Chao MV, Barker PA, Teng HK, Hempstead BL, Carter BD.

Neuron. 2006 Apr 20;50(2):219-32.PMID: 16630834 [PubMed - indexed for MEDLINE]Related articles

AEG3482 is an antiapoptotic compound that inhibits Jun kinase activity and cell death through induced expression of heat shock protein 70.

Salehi AH, Morris SJ, Ho WC, Dickson KM, Doucet G, Milutinovic S, Durkin J, Gillard JW, Barker PA.

Chem Biol. 2006 Feb;13(2):213-23.PMID: 16492569 [PubMed - indexed for MEDLINE]Related articles

Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase beta-dependent mechanism.

Lora JM, Zhang DM, Liao SM, Burwell T, King AM, Barker PA, Singh L, Keaveney M, Morgenstern J, Gutiérrez-Ramos JC, Coyle AJ, Fraser CC.

J Biol Chem. 2005 Oct 28;280(43):36510-7. Epub 2005 Aug 25.PMID: 16123045 [PubMed - indexed for MEDLINE]Related articlesFree article

p75 neurotrophin receptor reduces ligand-induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation.

Makkerh JP, Ceni C, Auld DS, Vaillancourt F, Dorval G, Barker PA.

EMBO Rep. 2005 Oct;6(10):936-41.PMID: 16113645 [PubMed - indexed for MEDLINE]Related articlesFree article

Getting RIP'd Stunts Your Growth.

Ceni C, Barker PA.

Neuron. 2005 Jun 16;46(6):839-40.PMID: 15953410 [PubMed - indexed for MEDLINE]Related articles

Nuclear factor-kappaB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-kappaB-dependent transcription in cancer cells.

Ho WC, Dickson KM, Barker PA.

Cancer Res. 2005 May 15;65(10):4273-81.PMID: 15899819 [PubMed - indexed for MEDLINE]Related articlesFree article

Co-expression of the P75 neurotrophin receptor and neurotrophin receptor-interacting melanoma antigen homolog in the mature rat brain.

Barrett GL, Greferath U, Barker PA, Trieu J, Bennie A.

Neuroscience. 2005;133(2):381-92.PMID: 15878242 [PubMed - indexed for MEDLINE]Related articles

Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis.

Becker EB, Howell J, Kodama Y, Barker PA, Bonni A.

J Neurosci. 2004 Oct 6;24(40):8762-70. Erratum in: J Neurosci. 2004 Oct 27;24(43):1 p following 9722. PMID: 15470142 [PubMed - indexed for MEDLINE]Related articlesFree article

Conjugated linoleic acid inhibits proliferation and modulates protein kinase C isoforms in human prostate cancer cells.

Song HJ, Sneddon AA, Barker PA, Bestwick C, Choe SN, McClinton S, Grant I, Rotondo D, Heys SD, Wahle KW.

Nutr Cancer. 2004;49(1):100-8.PMID: 15456642 [PubMed - indexed for MEDLINE]Related articles

TRAF6-dependent NF-kB transcriptional activity during mouse development.

Dickson KM, Bhakar AL, Barker PA.

Dev Dyn. 2004 Sep;231(1):122-7.PMID: 15305292 [PubMed - indexed for MEDLINE]Related articlesFree article

p75NTR is positively promiscuous: novel partners and new insights.

Barker PA.

Neuron. 2004 May 27;42(4):529-33. Review.PMID: 15157416 [PubMed - indexed for MEDLINE]Related articles

The p75 neurotrophin receptor can induce autophagy and death of cerebellar Purkinje neurons.

Florez-McClure ML, Linseman DA, Chu CT, Barker PA, Bouchard RJ, Le SS, Laessig TA, Heidenreich KA.

J Neurosci. 2004 May 12;24(19):4498-509.PMID: 15140920 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase A activation promotes plasma membrane insertion of DCC from an intracellular pool: A novel mechanism regulating commissural axon extension.

Bouchard JF, Moore SW, Tritsch NX, Roux PP, Shekarabi M, Barker PA, Kennedy TE.

J Neurosci. 2004 Mar 24;24(12):3040-50.PMID: 15044543 [PubMed - indexed for MEDLINE]Related articlesFree article

A pro-apoptotic fragment of the p75 neurotrophin receptor is expressed in p75NTRExonIV null mice.

Paul CE, Vereker E, Dickson KM, Barker PA.

J Neurosci. 2004 Feb 25;24(8):1917-23.PMID: 14985432 [PubMed - indexed for MEDLINE]Related articlesFree article

The p75 neurotrophin receptor: multiple interactors and numerous functions.

Gentry JJ, Barker PA, Carter BD.

Prog Brain Res. 2004;146:25-39. Review.PMID: 14699954 [PubMed - indexed for MEDLINE]Related articles

Apoptosis induced by p75NTR overexpression requires Jun kinase-dependent phosphorylation of Bad.

Bhakar AL, Howell JL, Paul CE, Salehi AH, Becker EB, Said F, Bonni A, Barker PA.

J Neurosci. 2003 Dec 10;23(36):11373-81.PMID: 14673001 [PubMed - indexed for MEDLINE]Related articlesFree article

Hospital re-admission in children with non-specific abdominal pain.

Barker PA, Jutley RS, Youngson GG.

Pediatr Surg Int. 2002 Sep;18(5-6):341-3. Epub 2002 May 9.PMID: 12415351 [PubMed - indexed for MEDLINE]Related articles

K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK.

Roux PP, Dorval G, Boudreau M, Angers-Loustau A, Morris SJ, Makkerh J, Barker PA.

J Biol Chem. 2002 Dec 20;277(51):49473-80. Epub 2002 Oct 17.PMID: 12388555 [PubMed - indexed for MEDLINE]Related articlesFree article

NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.

Salehi AH, Xanthoudakis S, Barker PA.

J Biol Chem. 2002 Dec 13;277(50):48043-50. Epub 2002 Oct 9.PMID: 12376548 [PubMed - indexed for MEDLINE]Related articlesFree article

Constitutive nuclear factor-kappa B activity is required for central neuron survival.

Bhakar AL, Tannis LL, Zeindler C, Russo MP, Jobin C, Park DS, MacPherson S, Barker PA.

J Neurosci. 2002 Oct 1;22(19):8466-75.PMID: 12351721 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression analysis of a novel p75(NTR) signaling protein, which regulates cell cycle progression and apoptosis.

Kendall SE, Goldhawk DE, Kubu C, Barker PA, Verdi JM.

Mech Dev. 2002 Sep;117(1-2):187-200.PMID: 12204258 [PubMed - indexed for MEDLINE]Related articles

Neurotrophin signaling through the p75 neurotrophin receptor.

Roux PP, Barker PA.

Prog Neurobiol. 2002 Jun;67(3):203-33. Review.PMID: 12169297 [PubMed - indexed for MEDLINE]Related articles

Retrograde signaling by the neurotrophins follows a well-worn trk.

Barker PA, Hussain NK, McPherson PS.

Trends Neurosci. 2002 Aug;25(8):379-81. Review.PMID: 12127743 [PubMed - indexed for MEDLINE]Related articles

The MAGE proteins: emerging roles in cell cycle progression, apoptosis, and neurogenetic disease.

Barker PA, Salehi A.

J Neurosci Res. 2002 Mar 15;67(6):705-12. Review.PMID: 11891783 [PubMed - indexed for MEDLINE]Related articles

A 14,000-year oxygen isotope record from diatom silica in two alpine lakes on Mt. Kenya.

Barker PA, Street-Perrott FA, Leng MJ, Greenwood PB, Swain DL, Perrott RA, Telford RJ, Ficken KJ.

Science. 2001 Jun 22;292(5525):2307-10.PMID: 11423656 [PubMed - indexed for MEDLINE]Related articlesFree article

The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway.

Roux PP, Bhakar AL, Kennedy TE, Barker PA.

J Biol Chem. 2001 Jun 22;276(25):23097-104. Epub 2001 Apr 18.PMID: 11312266 [PubMed - indexed for MEDLINE]Related articlesFree article

The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor.

Wooten MW, Seibenhener ML, Mamidipudi V, Diaz-Meco MT, Barker PA, Moscat J.

J Biol Chem. 2001 Mar 16;276(11):7709-12. Epub 2001 Jan 22.PMID: 11244088 [PubMed - indexed for MEDLINE]Related articlesFree article

TTIP is a novel protein that interacts with the truncated T1 TrkB neurotrophin receptor.

Kryl D, Barker PA.

Biochem Biophys Res Commun. 2000 Dec 29;279(3):925-30.PMID: 11162451 [PubMed - indexed for MEDLINE]Related articles

Identification of the translational initiation codon in human MAGED1.

Kubu CJ, Goldhawk DG, Barker PA, Verdi JM.

Genomics. 2000 Nov 15;70(1):150-2. No abstract available. PMID: 11087672 [PubMed - indexed for MEDLINE]Related articles