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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1969 1
1975 2
1976 3
1977 2
1978 4
1979 1
1980 1
1981 1
1982 2
1983 3
1984 3
1985 2
1986 5
1987 7
1988 5
1989 7
1990 7
1991 8
1992 16
1993 13
1994 20
1995 16
1996 14
1997 18
1998 32
1999 28
2000 29
2001 30
2002 40
2003 22
2004 35
2005 46
2006 33
2007 32
2008 38
2009 41
2010 48
2011 44
2012 38
2013 44
2014 50
2015 53
2016 45
2017 58
2018 58
2019 60
2020 55
2021 52
2022 47
2023 44
2024 19

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1,146 results

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Page 1
CD169(+) macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair.
Batoon L, Millard SM, Wullschleger ME, Preda C, Wu AC, Kaur S, Tseng HW, Hume DA, Levesque JP, Raggatt LJ, Pettit AR. Batoon L, et al. Biomaterials. 2019 Mar;196:51-66. doi: 10.1016/j.biomaterials.2017.10.033. Epub 2017 Oct 22. Biomaterials. 2019. PMID: 29107337 Free article.
The impact of CD169(+) macrophage depletion was assessed in two models of bone injury that heal via either intramembranous (tibial injury) or endochondral (internally-plated femoral fracture model) ossification. ...
The impact of CD169(+) macrophage depletion was assessed in two models of bone injury that heal via either intramembranous (tibial in …
Bone development.
Berendsen AD, Olsen BR. Berendsen AD, et al. Bone. 2015 Nov;80:14-18. doi: 10.1016/j.bone.2015.04.035. Bone. 2015. PMID: 26453494 Free PMC article. Review.
This review describes the processes that result in endochondral and intramembranous ossification, the important roles of growth and transcription factors, and the consequences of mutations in some of the genes involved. ...
This review describes the processes that result in endochondral and intramembranous ossification, the important roles of growt …
Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence.
Saul D, Khosla S. Saul D, et al. Endocr Rev. 2022 Nov 25;43(6):984-1002. doi: 10.1210/endrev/bnac008. Endocr Rev. 2022. PMID: 35182420 Free PMC article. Review.
While the initial hematoma generates an inflammatory environment in which mesenchymal stem cells and macrophages orchestrate the framework for repair, angiogenesis and cartilage formation mark the second healing period. In the central region, endochondral ossification favo …
While the initial hematoma generates an inflammatory environment in which mesenchymal stem cells and macrophages orchestrate the framework f …
Osteoblast-derived VEGF regulates osteoblast differentiation and bone formation during bone repair.
Hu K, Olsen BR. Hu K, et al. J Clin Invest. 2016 Feb;126(2):509-26. doi: 10.1172/JCI82585. Epub 2016 Jan 5. J Clin Invest. 2016. PMID: 26731472 Free PMC article.
Using transgenic mice with osteoblast-specific deletion of Vegfa, we demonstrated that VEGF promoted macrophage recruitment and angiogenic responses in the inflammation phase, and optimal levels of VEGF were required for coupling of angiogenesis and osteogenesis in areas w …
Using transgenic mice with osteoblast-specific deletion of Vegfa, we demonstrated that VEGF promoted macrophage recruitment and angiogenic r …
Regulation and Role of Transcription Factors in Osteogenesis.
Chan WCW, Tan Z, To MKT, Chan D. Chan WCW, et al. Int J Mol Sci. 2021 May 21;22(11):5445. doi: 10.3390/ijms22115445. Int J Mol Sci. 2021. PMID: 34064134 Free PMC article. Review.
Osteoblasts secrete matrix, with some being buried within the newly formed bone, and differentiate to osteocytes. During embryogenesis, bones are formed through intramembraneous or endochondral ossification. The former involves a direct differentiation of mesenchyma …
Osteoblasts secrete matrix, with some being buried within the newly formed bone, and differentiate to osteocytes. During embryogenesis, bone …
Angiogenesis and intramembranous osteogenesis.
Percival CJ, Richtsmeier JT. Percival CJ, et al. Dev Dyn. 2013 Aug;242(8):909-22. doi: 10.1002/dvdy.23992. Epub 2013 Jun 27. Dev Dyn. 2013. PMID: 23737393 Free PMC article. Review.
BACKGROUND: Angiogenesis is likely critical for the process of intramembranous osteogenesis; however, the developmental relationship between blood vessels and bone mineralization is not well studied within intramembranous bones. ...RESULTS: We summarize what …
BACKGROUND: Angiogenesis is likely critical for the process of intramembranous osteogenesis; however, the developmental relati …
Making and shaping endochondral and intramembranous bones.
Galea GL, Zein MR, Allen S, Francis-West P. Galea GL, et al. Dev Dyn. 2021 Mar;250(3):414-449. doi: 10.1002/dvdy.278. Epub 2020 Dec 28. Dev Dyn. 2021. PMID: 33314394 Free PMC article. Review.
During embryonic development, bone forms by endochondral or intramembranous ossification and can arise from the paraxial and lateral plate mesoderm or neural crest. ...Specialized cellular behaviors, such as chondrocyte hypertrophy in endochondral bone and secondary …
During embryonic development, bone forms by endochondral or intramembranous ossification and can arise from the paraxial and l …
Distinct Morphologies of Bone Apatite Clusters in Endochondral and Intramembranous Ossification.
Hara ES, Nagaoka N, Okada M, Nakano T, Matsumoto T. Hara ES, et al. Adv Biol (Weinh). 2022 Nov;6(11):e2200076. doi: 10.1002/adbi.202200076. Epub 2022 Jul 20. Adv Biol (Weinh). 2022. PMID: 35859256
This study compares the structural and compositional differences between bone apatite clusters formed in intramembranous (IO) and endochondral ossification (EO). Calvaria (IO) and femurs (EO) are isolated from mice at embryonic days (E) 14.5 to 15.5 and post-natal d …
This study compares the structural and compositional differences between bone apatite clusters formed in intramembranous (IO) and end …
Intramembranous ossification and endochondral ossification are impaired differently between glucocorticoid-induced osteoporosis and estrogen deficiency-induced osteoporosis.
Zhang H, Shi X, Wang L, Li X, Zheng C, Gao B, Xu X, Lin X, Wang J, Lin Y, Shi J, Huang Q, Luo Z, Yang L. Zhang H, et al. Sci Rep. 2018 Mar 1;8(1):3867. doi: 10.1038/s41598-018-22095-1. Sci Rep. 2018. PMID: 29497100 Free PMC article.
Osteoporosis impairs fracture healing and prognosis, but how intramembranous ossification (IO) or endochondral ossification (EO) during fracture healing are affected and whether these two kinds of ossification are different between glucocorticoid-induc …
Osteoporosis impairs fracture healing and prognosis, but how intramembranous ossification (IO) or endochondral ossification …
Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses.
He J, Yan J, Wang J, Zhao L, Xin Q, Zeng Y, Sun Y, Zhang H, Bai Z, Li Z, Ni Y, Gong Y, Li Y, He H, Bian Z, Lan Y, Ma C, Bian L, Zhu H, Liu B, Yue R. He J, et al. Cell Res. 2021 Jul;31(7):742-757. doi: 10.1038/s41422-021-00467-z. Epub 2021 Jan 20. Cell Res. 2021. PMID: 33473154 Free PMC article.
Osteo-chondrogenic progenitors first appeared in the core limb bud mesenchyme, which give rise to multiple populations of stem/progenitor cells in embryonic long bones undergoing endochondral ossification. Importantly, a perichondrial embryonic skeletal stem/progenitor cel …
Osteo-chondrogenic progenitors first appeared in the core limb bud mesenchyme, which give rise to multiple populations of stem/progenitor ce …
1,146 results