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1953 2
1955 2
1956 2
1957 3
1958 1
1959 2
1960 3
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1963 8
1964 12
1965 3
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1967 20
1968 19
1969 24
1970 30
1971 25
1972 34
1973 22
1974 25
1975 149
1976 155
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1978 127
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2012 806
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Page 1
Mechanisms of heart valve development and disease.
O'Donnell A, Yutzey KE. O'Donnell A, et al. Development. 2020 Jul 3;147(13):dev183020. doi: 10.1242/dev.183020. Development. 2020. PMID: 32620577 Free PMC article. Review.
Heart valve development is regulated by complex interactions between different cardiac cell types and is subject to blood flow-driven forces. ...Furthermore, this work has revealed that many key genetic pathways involved in cardiac valve development …
Heart valve development is regulated by complex interactions between different cardiac cell types and is subject to blo …
Development of the human heart.
Buijtendijk MFJ, Barnett P, van den Hoff MJB. Buijtendijk MFJ, et al. Am J Med Genet C Semin Med Genet. 2020 Mar;184(1):7-22. doi: 10.1002/ajmg.c.31778. Epub 2020 Feb 12. Am J Med Genet C Semin Med Genet. 2020. PMID: 32048790 Free PMC article. Review.
In 2014, an extensive review discussing the major steps of cardiac development focusing on growth, formation of primary and chamber myocardium and the development of the cardiac electrical system, was published. ...The challenge for the next decade will be to …
In 2014, an extensive review discussing the major steps of cardiac development focusing on growth, formation of primary and ch …
Macrophage lineages in heart valve development and disease.
Kim AJ, Xu N, Yutzey KE. Kim AJ, et al. Cardiovasc Res. 2021 Feb 22;117(3):663-673. doi: 10.1093/cvr/cvaa062. Cardiovasc Res. 2021. PMID: 32170926 Free PMC article. Review.
During myxomatous heart valve disease, monocyte-derived macrophages are recruited to the heart valves and they contribute to valve degeneration in a mouse model of Marfan syndrome. Here, we review recent studies of macrophage lineages in hear …
During myxomatous heart valve disease, monocyte-derived macrophages are recruited to the heart valves and they c …
Strategies for development of decellularized heart valve scaffolds for tissue engineering.
Snyder Y, Jana S. Snyder Y, et al. Biomaterials. 2022 Sep;288:121675. doi: 10.1016/j.biomaterials.2022.121675. Epub 2022 Jul 18. Biomaterials. 2022. PMID: 35953330 Review.
These scaffolds provide three-dimensional supports for cellular adhesion and growth, leading to tissue formation and, finally, a new functional heart valve development. ...We also examine the predominant issues in scaffold development. Further, …
These scaffolds provide three-dimensional supports for cellular adhesion and growth, leading to tissue formation and, finally, a new …
Heart valve development, maintenance, and disease: the role of endothelial cells.
Tao G, Kotick JD, Lincoln J. Tao G, et al. Curr Top Dev Biol. 2012;100:203-32. doi: 10.1016/B978-0-12-387786-4.00006-3. Curr Top Dev Biol. 2012. PMID: 22449845 Review.
Heart valves are dynamic structures that open and close during the cardiac cycle to maintain unidirectional blood flow throughout life. ...Increasing our understanding of the roles of VECs in development and disease has lead to promising advances in the de …
Heart valves are dynamic structures that open and close during the cardiac cycle to maintain unidirectional blood flow through …
Endothelial Cyp26b1 restrains murine heart valve growth during development.
Ahuja N, Hiltabidle MS, Rajasekhar H, Voss S, Lu SZ, Barlow HR, Cowdin MA, Daniel E, Vaddaraju V, Anandakumar T, Black E, Cleaver O, Maynard C. Ahuja N, et al. Dev Biol. 2022 Jun;486:81-95. doi: 10.1016/j.ydbio.2022.03.003. Epub 2022 Mar 29. Dev Biol. 2022. PMID: 35364055 Free article.
Endothelial cells (ECs) are critical to proper heart valve development, directly contributing to the mesenchyme of the cardiac cushions, which progressively transform into mature valves. ...We identified Cyp26b1 as one of many endothelial enriched gene …
Endothelial cells (ECs) are critical to proper heart valve development, directly contributing to the mesenchyme of the …
Heart valve development: regulatory networks in development and disease.
Combs MD, Yutzey KE. Combs MD, et al. Circ Res. 2009 Aug 28;105(5):408-21. doi: 10.1161/CIRCRESAHA.109.201566. Circ Res. 2009. PMID: 19713546 Free PMC article. Review.
In recent years, significant advances have been made in the definition of regulatory pathways that control normal and abnormal cardiac valve development. Here, we review the cellular and molecular mechanisms underlying the early development of valve pr …
In recent years, significant advances have been made in the definition of regulatory pathways that control normal and abnormal cardiac va …
Mechanical considerations for polymeric heart valve development: Biomechanics, materials, design and manufacturing.
Li RL, Russ J, Paschalides C, Ferrari G, Waisman H, Kysar JW, Kalfa D. Li RL, et al. Biomaterials. 2019 Dec;225:119493. doi: 10.1016/j.biomaterials.2019.119493. Epub 2019 Sep 17. Biomaterials. 2019. PMID: 31569017 Free PMC article. Review.
The native human heart valve leaflet contains a layered microstructure comprising a hierarchical arrangement of collagen, elastin, proteoglycans and various cell types. ...The latter portion of this review recounts these developments in polymeric heart …
The native human heart valve leaflet contains a layered microstructure comprising a hierarchical arrangement of collagen, elas …
Heart valve structure and function in development and disease.
Hinton RB, Yutzey KE. Hinton RB, et al. Annu Rev Physiol. 2011;73:29-46. doi: 10.1146/annurev-physiol-012110-142145. Annu Rev Physiol. 2011. PMID: 20809794 Free PMC article. Review.
The mature heart valves are made up of highly organized extracellular matrix (ECM) and valve interstitial cells (VICs) surrounded by an endothelial cell layer. ...Signaling pathways have critical functions in primary valvulogenesis as well as the maintenance …
The mature heart valves are made up of highly organized extracellular matrix (ECM) and valve interstitial cells (VICs) …
Endothelial-to-Mesenchymal Transition.
Bischoff J. Bischoff J. Circ Res. 2019 Apr 12;124(8):1163-1165. doi: 10.1161/CIRCRESAHA.119.314813. Circ Res. 2019. PMID: 30973806 Free PMC article. Review.
EndMT is an intricate cellular differentiation process whereby endothelial cells detach and migrate away from the endothelium and, to varying extents, decrease endothelial properties and acquire mesenchymal features. First described in developing heart valves …
EndMT is an intricate cellular differentiation process whereby endothelial cells detach and migrate away from the endothelium and, to varyin …
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Searches related to "heart valve development"