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Circ_ZFP644 attenuates caerulein-induced inflammatory injury in rat pancreatic acinar cells by modulating miR-106b/Pias3 axis.
Wang J, Fu J, Xu C, Jia R, Zhang X, Zhao S. Wang J, et al. Exp Mol Pathol. 2021 Aug;121:104644. doi: 10.1016/j.yexmp.2021.104644. Epub 2021 May 1. Exp Mol Pathol. 2021. PMID: 33945806
Western blot assay was also conducted to analyze the expression of apoptosis-related proteins. The association among circ_ZFP644, miR-106b and Pias3 was validated by dual-luciferase reporter assay. ...Circ_ZFP644 targeted miR-106b to upregulate Pias3 expression. Cir …
Western blot assay was also conducted to analyze the expression of apoptosis-related proteins. The association among circ_ZFP644, miR …
Circ-Zfp644 acts as a pro-hypertrophic mediator in an Ang-II induced in vitro myocardial hypertrophy model.
Chen Y, Song D, Gao J, Zhang X, Chen X. Chen Y, et al. Cell Biol Int. 2021 Jun;45(6):1260-1268. doi: 10.1002/cbin.11569. Epub 2021 Mar 25. Cell Biol Int. 2021. PMID: 33559936
Next, through a series of mechanistic assays including RIP assay, RNA pull-down assay, and luciferase reporter assay, miR-93-5p was verified to target Limk1. Furthermore, circ-Zfp644 was validated as the sponge of miR-93-5p. Circ-Zfp644 functioned as a ceRNA to upre …
Next, through a series of mechanistic assays including RIP assay, RNA pull-down assay, and luciferase reporter assay, miR-93-5p was verified …
Myopia disease mouse models: a missense point mutation (S673G) and a protein-truncating mutation of the Zfp644 mimic human disease phenotype.
Szczerkowska KI, Petrezselyova S, Lindovsky J, Palkova M, Dvorak J, Makovicky P, Fang M, Jiang C, Chen L, Shi M, Liu X, Zhang J, Kubik-Zahorodna A, Schuster B, Beck IM, Novosadova V, Prochazka J, Sedlacek R. Szczerkowska KI, et al. Cell Biosci. 2019 Feb 21;9:21. doi: 10.1186/s13578-019-0280-4. eCollection 2019. Cell Biosci. 2019. PMID: 30834109 Free PMC article.
Employing TALEN technology, two mice mutants were generated, either with the disease-carrying mutation (Zfp644 (S673G) ) or with a truncated form of Zfp644 (Zfp644 (delta8) ). Eye morphology and visual functions were analysed in both mutants, revealing a sign …
Employing TALEN technology, two mice mutants were generated, either with the disease-carrying mutation (Zfp644 (S673G) ) or with a tr …
Implication of NOTCH1 gene in susceptibility to anxiety and depression among sexual abuse victims.
Steine IM, Zayats T, Stansberg C, Pallesen S, Mrdalj J, Håvik B, Soulé J, Haavik J, Milde AM, Skrede S, Murison R, Krystal J, Grønli J. Steine IM, et al. Transl Psychiatry. 2016 Dec 13;6(12):e977. doi: 10.1038/tp.2016.248. Transl Psychiatry. 2016. PMID: 27959334 Free PMC article.
We identified four genes showing differential expression among animals subjected to different early-life conditions as well as having potential relevance to neural development or disorders: Notch1, Gabrr1, Plk5 and Zfp644. In the human sample, significant associations were …
We identified four genes showing differential expression among animals subjected to different early-life conditions as well as having potent …