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Novel gene markers of immunosuppressive chemicals in mouse lymph node assay.
Oshida K, Maeda A, Kitsukawa M, Suga S, Iwano S, Miyoshi T, Miyamoto Y. Oshida K, et al. Toxicol Lett. 2011 Aug 10;205(1):79-85. doi: 10.1016/j.toxlet.2011.05.1017. Epub 2011 May 20. Toxicol Lett. 2011. PMID: 21621594
We performed a comprehensive analysis of results of gene expression in lymph nodes obtained in the LLNA using a highly sensitive DNA chip, 3D-Gene, and the quantitative reverse transcription-polymerase chain reaction (qPCR). Zfp459 expression increased in all animals treat …
We performed a comprehensive analysis of results of gene expression in lymph nodes obtained in the LLNA using a highly sensitive DNA chip, 3 …
Immunosuppressive potential of bardoxolone methyl using a modified murine local lymph node assay (LLNA).
Kitsukawa M, Tsuchiyama H, Maeda A, Oshida K, Miyamoto Y. Kitsukawa M, et al. J Toxicol Sci. 2014 Aug;39(4):545-50. doi: 10.2131/jts.39.545. J Toxicol Sci. 2014. PMID: 25056779 Free article.
In the modified LLNA, CDDO-Me showed a significant decrease in lymph node weight and changes in expressions of the immunosuppression-related genes, Zfp459 and Fmo2. It has been already reported that a decrease in lymph node weight was induced by several types of immunosupp …
In the modified LLNA, CDDO-Me showed a significant decrease in lymph node weight and changes in expressions of the immunosuppression-related …