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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 6
2002 4
2005 2
2006 1
2007 3
2008 5
2009 1
2011 2
2012 4
2013 2
2014 1
2016 4
2019 1
2020 1
2021 1
2022 3
2023 3
2024 1

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42 results

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ELK1 suppresses SYTL1 expression by recruiting HDAC2 in bladder cancer progression.
Wang J, Luo J, Wu X, Li Z. Wang J, et al. Hum Cell. 2022 Nov;35(6):1961-1975. doi: 10.1007/s13577-022-00789-z. Epub 2022 Sep 15. Hum Cell. 2022. PMID: 36107384
Further analysis revealed that ELK1 synergized with histone deacetylase 2 (HDAC2) to specifically bind to the synaptotagmin like 1 (SYTL1) promoter, thereby repressing SYTL1 transcription and protein expression. Depletion of SYTL1 reversed the repressive effe …
Further analysis revealed that ELK1 synergized with histone deacetylase 2 (HDAC2) to specifically bind to the synaptotagmin like 1 (SYTL1 …
LincRNA01703 Facilitates CD81(+) Exosome Secretion to Inhibit Lung Adenocarcinoma Metastasis via the Rab27a/SYTL1/CD81 Complex.
Huang Y, Guo S, Lin Y, Huo L, Yan H, Lin Z, Chen Z, Cai J, Wu J, Yuan J, Guan H, Wu G, Wu W, Tao T. Huang Y, et al. Cancers (Basel). 2023 Dec 9;15(24):5781. doi: 10.3390/cancers15245781. Cancers (Basel). 2023. PMID: 38136327 Free PMC article.
Mechanistically, Linc01703 enhanced the interaction between Rab27a, SYTL1, and CD81, consequently promoting the secretion of CD81(+) exosomes. ...Collectively, our findings suggest that Linc01703 functions as a metastasis suppressor by facilitating the secretion of CD81(+) …
Mechanistically, Linc01703 enhanced the interaction between Rab27a, SYTL1, and CD81, consequently promoting the secretion of CD81(+) …
WTAP enhances the instability of SYTL1 mRNA caused by YTHDF2 in bladder cancer.
Wang J, Luo J, Wu X, Li Z. Wang J, et al. Histol Histopathol. 2024 May;39(5):633-646. doi: 10.14670/HH-18-671. Epub 2023 Oct 23. Histol Histopathol. 2024. PMID: 37933909
METHODS: The prognostic role of SYTL1 in BCa was investigated using bioinformatics analysis, and the correlation between SYTL1 expression and NK cells was analyzed. ...SYTL1 inhibited the BCa progression in mice while enhancing the anti-tumor response of NK c …
METHODS: The prognostic role of SYTL1 in BCa was investigated using bioinformatics analysis, and the correlation between SYTL1 …
Synaptotagmin-like protein 1 is a potential diagnostic and prognostic biomarker in endometrial cancer based on bioinformatics and experiments.
Meijuan C, Meng X, Fang L, Qian W. Meijuan C, et al. J Ovarian Res. 2023 Jan 19;16(1):16. doi: 10.1186/s13048-023-01097-2. J Ovarian Res. 2023. PMID: 36653850 Free PMC article.
And increased expression of SYTL1 was associated with age, clinical stage, histological type, histological grade and good overall survival (OS).SYTL1 DNA methylation is negatively associated with SYTL1 expression and UCEC patients' OS. SYTL1 expression …
And increased expression of SYTL1 was associated with age, clinical stage, histological type, histological grade and good overall sur …
MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis.
Yokoyama T, Nakatake M, Kuwata T, Couzinet A, Goitsuka R, Tsutsumi S, Aburatani H, Valk PJ, Delwel R, Nakamura T. Yokoyama T, et al. J Clin Invest. 2016 May 2;126(5):1664-78. doi: 10.1172/JCI81516. Epub 2016 Mar 28. J Clin Invest. 2016. PMID: 27018596 Free PMC article.
Replacement of SYTL1 in MEIS1-deficent cells restored both cell migration and engraftment. Further analysis revealed that SYTL1 promotes cell migration via activation of the CXCL12/CXCR4 axis, as SYTL1 determines intracellular trafficking of CXCR4. ...
Replacement of SYTL1 in MEIS1-deficent cells restored both cell migration and engraftment. Further analysis revealed that SYTL1 …
Exploration of Prognostic Biomarkers of Muscle-Invasive Bladder Cancer (MIBC) by Bioinformatics.
Xu X, Wang Y, Zhang S, Zhu Y, Wang J. Xu X, et al. Evol Bioinform Online. 2021 Oct 28;17:11769343211049270. doi: 10.1177/11769343211049270. eCollection 2021. Evol Bioinform Online. 2021. PMID: 34733102 Free PMC article.
MIBC samples from TCGA and GEO were analyzed by WGCNA and univariate Cox analysis and intersected at 4 genes, CLK4, DEDD2, ENO1, and SYTL1. Higher SYTL1 and DEDD2 expressions were significantly correlated with high tumor grades. ...
MIBC samples from TCGA and GEO were analyzed by WGCNA and univariate Cox analysis and intersected at 4 genes, CLK4, DEDD2, ENO1, and SYTL …
Genome-Wide Identification of Immune-Related Alternative Splicing and Splicing Regulators Involved in Abdominal Aortic Aneurysm.
Wu S, Liu S, Chen N, Zhang C, Zhang H, Guo X. Wu S, et al. Front Genet. 2022 Feb 17;13:816035. doi: 10.3389/fgene.2022.816035. eCollection 2022. Front Genet. 2022. PMID: 35251127 Free PMC article.
Two downregulated genes, Nr4a1 and Nr4a2, and eight upregulated genes, Adipor2, Akt2, Bcl3, Dhx58, Pparg, Ptgds, Sytl1, and Vegfa were identified among the immune-related genes with RAS and DEGs. ...
Two downregulated genes, Nr4a1 and Nr4a2, and eight upregulated genes, Adipor2, Akt2, Bcl3, Dhx58, Pparg, Ptgds, Sytl1, and Vegfa wer …
Development and verification of a hypoxia- and immune-associated prognosis signature for esophageal squamous cell carcinoma.
Lian L, Teng SB, Xia YY, Shen XM, Zheng Y, Han SG, Wang WJ, Xu XF, Zhou C. Lian L, et al. J Gastrointest Oncol. 2022 Apr;13(2):462-477. doi: 10.21037/jgo-22-69. J Gastrointest Oncol. 2022. PMID: 35557566 Free PMC article.
RESULTS: A total of 73 intersecting genes were obtained as DEHRGs and a total of 548 intersecting genes were obtained as DEIRGs. The risk score was established using 8 genes (FABP7, TLR1, SYTL1, APLN, OSM, EGFR, IL17RD, MYH9) acquired from univariate Cox analysis. ...
RESULTS: A total of 73 intersecting genes were obtained as DEHRGs and a total of 548 intersecting genes were obtained as DEIRGs. The risk sc …
Deregulation of Rab and Rab effector genes in bladder cancer.
Ho JR, Chapeaublanc E, Kirkwood L, Nicolle R, Benhamou S, Lebret T, Allory Y, Southgate J, Radvanyi F, Goud B. Ho JR, et al. PLoS One. 2012;7(6):e39469. doi: 10.1371/journal.pone.0039469. Epub 2012 Jun 19. PLoS One. 2012. PMID: 22724020 Free PMC article.
Five of these deregulated genes (LEPRE1, MICAL2, RAB23, STXBP1, SYTL1) were specifically deregulated in FGFR3-non-mutated muscle-invasive tumors. ...
Five of these deregulated genes (LEPRE1, MICAL2, RAB23, STXBP1, SYTL1) were specifically deregulated in FGFR3-non-mutated muscle-inva …
The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration.
Ramadass M, Johnson JL, Marki A, Zhang J, Wolf D, Kiosses WB, Pestonjamasp K, Ley K, Catz SD. Ramadass M, et al. J Leukoc Biol. 2019 Jun;105(6):1209-1224. doi: 10.1002/JLB.1VMA0818-320R. Epub 2019 Feb 12. J Leukoc Biol. 2019. PMID: 30748033 Free PMC article.
Here, we identified a mechanism mediated by the trafficking protein synaptotagmin-like 1 (SYTL1 or JFC1) that controls Rac1-GTP recycling from the uropod and promotes directional migration of neutrophils. ...
Here, we identified a mechanism mediated by the trafficking protein synaptotagmin-like 1 (SYTL1 or JFC1) that controls Rac1-GTP recyc …
42 results