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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1998 1
1999 1
2000 4
2001 6
2002 5
2003 6
2004 3
2005 10
2006 6
2007 10
2008 11
2009 18
2010 13
2011 20
2012 18
2013 15
2014 19
2015 27
2016 24
2017 22
2018 13
2019 12
2020 18
2021 19
2022 6
2023 8
2024 4

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284 results

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Page 1
SynPo-Net-Accurate and Fast CNN-Based 6DoF Object Pose Estimation Using Synthetic Training.
Su Y, Rambach J, Pagani A, Stricker D. Su Y, et al. Sensors (Basel). 2021 Jan 5;21(1):300. doi: 10.3390/s21010300. Sensors (Basel). 2021. PMID: 33466293 Free PMC article.
This paper presents a novel approach using a Convolutional Neural Network (CNN) trained exclusively on single-channel Synthetic images of objects to regress 6DoF object Poses directly (SynPo-Net). The proposed SynPo-Net is a network architecture specifically designe …
This paper presents a novel approach using a Convolutional Neural Network (CNN) trained exclusively on single-channel Synthetic images of ob …
The chaperone-assisted selective autophagy complex dynamics and dysfunctions.
Tedesco B, Vendredy L, Timmerman V, Poletti A. Tedesco B, et al. Autophagy. 2023 Jun;19(6):1619-1641. doi: 10.1080/15548627.2022.2160564. Epub 2023 Jan 3. Autophagy. 2023. PMID: 36594740 Free PMC article.
We also briefly discuss how CASA complex proteins are involved in disease and may represent an interesting therapeutic target.Abbreviation ALP: autophagy lysosomal pathway; ALS: amyotrophic lateral sclerosis; AMOTL1: angiomotin like 1; ARP2/3: actin related protein 2/3; BAG: BAG …
We also briefly discuss how CASA complex proteins are involved in disease and may represent an interesting therapeutic target.Abbreviation A …
Autism-related KLHL17 and SYNPO act in concert to control activity-dependent dendritic spine enlargement and the spine apparatus.
Hu HT, Lin YJ, Wang UT, Lee SP, Liou YH, Chen BC, Hsueh YP. Hu HT, et al. PLoS Biol. 2023 Aug 31;21(8):e3002274. doi: 10.1371/journal.pbio.3002274. eCollection 2023 Aug. PLoS Biol. 2023. PMID: 37651441 Free PMC article.
Our super-resolution imaging using expansion microscopy demonstrates that SYNPO is indeed embedded into the ER network of dendritic spines and that KLHL17 is closely adjacent to the ER/SYNPO complex. ...In addition, we show that the effect of disrupting the KLHL17 a …
Our super-resolution imaging using expansion microscopy demonstrates that SYNPO is indeed embedded into the ER network of dendritic s …
BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes.
Ji C, Tang M, Zeidler C, Höhfeld J, Johnson GV. Ji C, et al. Autophagy. 2019 Jul;15(7):1199-1213. doi: 10.1080/15548627.2019.1580096. Epub 2019 Mar 1. Autophagy. 2019. PMID: 30744518 Free PMC article.
Here we demonstrate for the first time that BAG3 plays an important role in autophagic flux in the neurites of mature neurons (20-24 days in vitro [DIV]) through interaction with the post-synaptic cytoskeleton protein SYNPO (synaptopodin). Loss of either BAG3 or SYNPO …
Here we demonstrate for the first time that BAG3 plays an important role in autophagic flux in the neurites of mature neurons (20-24 days in …
Synaptopodin deficiency exacerbates kidney disease in a mouse model of Alport syndrome.
Ning L, Suleiman HY, Miner JH. Ning L, et al. Am J Physiol Renal Physiol. 2021 Jul 1;321(1):F12-F25. doi: 10.1152/ajprenal.00035.2021. Epub 2021 May 24. Am J Physiol Renal Physiol. 2021. PMID: 34029143 Free PMC article.
By generating mice that completely lack Synpo, we previously showed that Synpo is dispensable for normal kidney function. However, lack of Synpo worsened adriamycin-induced nephropathy, indicating a protective role for Synpo in injured podocytes. ...
By generating mice that completely lack Synpo, we previously showed that Synpo is dispensable for normal kidney function. Howe …
Synaptopodin Is Dispensable for Normal Podocyte Homeostasis but Is Protective in the Context of Acute Podocyte Injury.
Ning L, Suleiman HY, Miner JH. Ning L, et al. J Am Soc Nephrol. 2020 Dec;31(12):2815-2832. doi: 10.1681/ASN.2020050572. Epub 2020 Sep 16. J Am Soc Nephrol. 2020. PMID: 32938649 Free PMC article.
Naturally occurring Synpo isoforms are known (Synpo-short and -long), and a novel truncated version (Synpo-T) is upregulated in podocytes from Synpo mutant mice. Synpo-T maintains some Synpo functions, which may prevent a podocyte phenoty …
Naturally occurring Synpo isoforms are known (Synpo-short and -long), and a novel truncated version (Synpo-T) is upregu …
Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.
Asanuma K, Kim K, Oh J, Giardino L, Chabanis S, Faul C, Reiser J, Mundel P. Asanuma K, et al. J Clin Invest. 2005 May;115(5):1188-98. doi: 10.1172/JCI23371. Epub 2005 Apr 1. J Clin Invest. 2005. PMID: 15841212 Free PMC article.
We further demonstrate that synaptopodin exists in 3 isoforms, neuronal Synpo-short (685 AA), renal Synpo-long (903 AA), and Synpo-T (181 AA). ...Gene silencing of Synpo-T abrogates stress-fiber formation in synpo(-/-) podocytes, demonstrating t …
We further demonstrate that synaptopodin exists in 3 isoforms, neuronal Synpo-short (685 AA), renal Synpo-long (903 AA), and …
Identification of rare copy number variations reveals PJA2, APCS, SYNPO, and TAC1 as novel candidate genes in Autism Spectrum Disorders.
Bitar T, Hleihel W, Marouillat S, Vonwill S, Vuillaume ML, Soufia M, Vourc'h P, Laumonnier F, Andres CR. Bitar T, et al. Mol Genet Genomic Med. 2019 Aug;7(8):e786. doi: 10.1002/mgg3.786. Epub 2019 Jun 29. Mol Genet Genomic Med. 2019. PMID: 31254375 Free PMC article.
Ten CNVs are de novo, 11 are inherited and one of unknown origin of transmission. Among the CNVs detected, novel ASD candidate genes PJA2, SYNPO, APCS, and TAC1 have been identified in our group of Lebanese patients. ...
Ten CNVs are de novo, 11 are inherited and one of unknown origin of transmission. Among the CNVs detected, novel ASD candidate genes PJA2, …
Functional analysis of promoter mutations in the ACTN4 and SYNPO genes in focal segmental glomerulosclerosis.
Dai S, Wang Z, Pan X, Wang W, Chen X, Ren H, Hao C, Han B, Chen N. Dai S, et al. Nephrol Dial Transplant. 2010 Mar;25(3):824-35. doi: 10.1093/ndt/gfp394. Epub 2009 Aug 7. Nephrol Dial Transplant. 2010. PMID: 19666657
Genomic DNA extracted from peripheral leukocytes of patients of healthy individuals were used to analyse the ACTN4 and SYNPO gene promoter mutations by polymerase chain reaction (PCR) and direct sequencing. ...So we presumed that the ACTN4 and SYNPO promoter mutatio …
Genomic DNA extracted from peripheral leukocytes of patients of healthy individuals were used to analyse the ACTN4 and SYNPO gene pro …
284 results