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2014 1
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2024 2

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Page 1
Polycystic Ovary Syndrome Physiologic Pathways Implicated Through Clustering of Genetic Loci.
Stamou MI, Smith KT, Kim H, Balasubramanian R, Gray KJ, Udler MS. Stamou MI, et al. J Clin Endocrinol Metab. 2024 Mar 15;109(4):968-977. doi: 10.1210/clinem/dgad664. J Clin Endocrinol Metab. 2024. PMID: 37967238
RESULTS: Four PCOS genetic clusters were identified with top loci indicated as following: (i) cluster 1/obesity/insulin resistance (FTO); (ii) cluster 2/hormonal/menstrual cycle changes (FSHB); (iii) cluster 3/blood markers/inflammation (ATXN2/SH2B3); (iv) cluster 4/metabolic cha …
RESULTS: Four PCOS genetic clusters were identified with top loci indicated as following: (i) cluster 1/obesity/insulin resistance (FTO); (i …
Transcriptome alterations in peripheral blood B cells of patients with multiple sclerosis receiving immune reconstitution therapy.
Hecker M, Fitzner B, Boxberger N, Putscher E, Engelmann R, Bergmann W, Müller M, Ludwig-Portugall I, Schwartz M, Meister S, Dudesek A, Winkelmann A, Koczan D, Zettl UK. Hecker M, et al. J Neuroinflammation. 2023 Aug 2;20(1):181. doi: 10.1186/s12974-023-02859-x. J Neuroinflammation. 2023. PMID: 37533036 Free PMC article.
The top DEGs were found to regulate apoptosis, cell adhesion and RNA processing, and the most highly connected nodes in the network of encoded proteins were ESR2, PHB and RC3H1. Higher mRNA levels of BCL2, IL13RA1 and SLC38A11 were seen in patients with relapse despite IRT …
The top DEGs were found to regulate apoptosis, cell adhesion and RNA processing, and the most highly connected nodes in the network of encod …
Knockdown of SLC38 Transporter Ortholog - CG13743 Reveals a Metabolic Relevance in Drosophila.
Aggarwal T, Patil S, Ceder M, Hayder M, Fredriksson R. Aggarwal T, et al. Front Physiol. 2020 Jan 21;10:1592. doi: 10.3389/fphys.2019.01592. eCollection 2019. Front Physiol. 2020. PMID: 32038282 Free PMC article.
Here, we show characteristics of Drosophila CG13743 which closely resembles SLC38A11 in humans. SLC38A11 still remains an orphan member of the SLC38 family which has not been functionally well studied. ...
Here, we show characteristics of Drosophila CG13743 which closely resembles SLC38A11 in humans. SLC38A11 still remains an orph …
Insight into the potential candidate genes and signaling pathways involved in lymphoma disease in dogs using a comprehensive whole blood transcriptome analysis.
Sheet S, Oh YI, Arora D, Choi BH, Ko M, Nam Y, Lim Y, Lim JA, Park M, Park W, Seo KW, Lee KT. Sheet S, et al. Gene. 2022 Sep 5;838:146735. doi: 10.1016/j.gene.2022.146735. Epub 2022 Jul 12. Gene. 2022. PMID: 35835403

At a false discovery rate (FDR) < 0.05 and fold change (FC) 1.5, a total of 625 differentially expressed genes (DEGs) were identified between lymphoma and non-lymphoma samples, including 347 up-regulated DEGs such as SLC38A11, SCN3A, ZIC5 etc. and 278 down-regulated DEG

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At a false discovery rate (FDR) < 0.05 and fold change (FC) 1.5, a total of 625 differentially expressed genes (DEGs) were identified bet

…
Identification of differentially expressed genes and splicing events in early-onset colorectal cancer.
Marx OM, Mankarious MM, Koltun WA, Yochum GS. Marx OM, et al. Front Oncol. 2024 Apr 11;14:1365762. doi: 10.3389/fonc.2024.1365762. eCollection 2024. Front Oncol. 2024. PMID: 38680862 Free PMC article.
RESULTS: We identified an eight-gene signature in EOCRC comprised of ALDOB, FBXL16, IL1RN, MSLN, RAC3, SLC38A11, WBSCR27 and WNT11, from which we developed a score predictive of overall CRC patient survival. ...
RESULTS: We identified an eight-gene signature in EOCRC comprised of ALDOB, FBXL16, IL1RN, MSLN, RAC3, SLC38A11, WBSCR27 and WNT11, f …
Nutritional Stress Induced by Amino Acid Starvation Results in Changes for Slc38 Transporters in Immortalized Hypothalamic Neuronal Cells and Primary Cortex Cells.
Hellsten SV, Tripathi R, Ceder MM, Fredriksson R. Hellsten SV, et al. Front Mol Biosci. 2018 May 8;5:45. doi: 10.3389/fmolb.2018.00045. eCollection 2018. Front Mol Biosci. 2018. PMID: 29868606 Free PMC article.
Here, protein level changes were measured for SLC38A7 and the orphan family member SLC38A11 which has not been studied under different amino acid starvation condition at protein level. At 5 h, no significant alteration on protein level for either SLC38A7 or SLC38A11 …
Here, protein level changes were measured for SLC38A7 and the orphan family member SLC38A11 which has not been studied under differen …
Amino acids in the uterine luminal fluid reflects the temporal changes in transporter expression in the endometrium and conceptus during early pregnancy in cattle.
Forde N, Simintiras CA, Sturmey R, Mamo S, Kelly AK, Spencer TE, Bazer FW, Lonergan P. Forde N, et al. PLoS One. 2014 Jun 24;9(6):e100010. doi: 10.1371/journal.pone.0100010. eCollection 2014. PLoS One. 2014. PMID: 24960174 Free PMC article.
The neutral AA transporters SLC38A2 and SLC7A5 increased in the endometrium in a temporal manner while conceptus expression of SLC38A7, SLC43A2, SLC38A11 and SLC7A8 also increased (P<0.05). P4 modified the expression of SLC1A1, -1A4, -1A5, -38A2, -38A4, -38A7, -43A2, -6 …
The neutral AA transporters SLC38A2 and SLC7A5 increased in the endometrium in a temporal manner while conceptus expression of SLC38A7, SLC4 …