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2001 1
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2022 5
2023 2
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NUDCD1 knockdown inhibits the proliferation, migration, and invasion of pancreatic cancer via the EMT process.
Shi C, Weng M, Zhu H, Guo Y, Xu D, Jin H, Wei B, Cao Z. Shi C, et al. Aging (Albany NY). 2021 Jul 29;13(14):18298-18309. doi: 10.18632/aging.203276. Epub 2021 Jul 29. Aging (Albany NY). 2021. PMID: 34325402 Free PMC article.
Thus, we aimed to determine the function and mechanism of NUDCD1 in PC. We employed Western blot and quantitative real-time polymerase chain reaction to assess NUDCD1 expression in cells and PC tissues. ...Also, we established a tumor xenograft model to determine th …
Thus, we aimed to determine the function and mechanism of NUDCD1 in PC. We employed Western blot and quantitative real-time polymeras …
Identifying the role of NUDCD1 in human tumors from clinical and molecular mechanisms: a study based on comprehensive bioinformatics and experimental validation.
Han B, He J, Chen Q, Yuan M, Zeng X, Li Y, Zeng Y, He M, Feng D, Ma D. Han B, et al. Aging (Albany NY). 2023 Jun 19;15(12):5611-5649. doi: 10.18632/aging.204813. Epub 2023 Jun 19. Aging (Albany NY). 2023. PMID: 37338527 Free PMC article.
NUDCD1 (NudC domain-containing 1) is abnormally activated in multiple tumors and has been identified as a cancer antigen. ...Multiple genetic and epigenetic features of NUDCD1 exist in different cancers. NUDCD1 was associated with expression levels of recogni …
NUDCD1 (NudC domain-containing 1) is abnormally activated in multiple tumors and has been identified as a cancer antigen. ...Multiple …
NudCD1 as a prognostic marker in colorectal cancer and its role in the upregulation of cellular spindle assembly checkpoint genes and LIS1 pathways.
Feng WM, Gong H, Wang YC, Wang Y, Xue T, Zhang T, Cui G. Feng WM, et al. BMC Cancer. 2022 Sep 14;22(1):981. doi: 10.1186/s12885-022-10041-4. BMC Cancer. 2022. PMID: 36104662 Free PMC article.

The Kaplan-Meier survival analysis showed that patients with high NudCD1 expression in colorectal cancer tissues had a significantly shorter survival time than those with low expression of NudCD1 (P < 0.01). ...CONCLUSION: NudCD1 can serve as a valuable pr

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The Kaplan-Meier survival analysis showed that patients with high NudCD1 expression in colorectal cancer tissues had a significantly …
NudCD1 affects renal cell carcinoma through regulating LIS1/Dynein signaling pathway.
He H, Dai J, Wang X, Qian X, Zhao J, Wang H, Xu D. He H, et al. Am J Transl Res. 2018 Feb 15;10(2):519-524. eCollection 2018. Am J Transl Res. 2018. PMID: 29511446 Free PMC article.
Overexpression of NudCD1 level in A498 cell line markedly elevated NudCD1/LIS1/Dynein signaling pathway, suggesting they might be involved in RCC process. ...NudCD1 expression was obviously increased in RCC and affected RCC cell division and migration possibl …
Overexpression of NudCD1 level in A498 cell line markedly elevated NudCD1/LIS1/Dynein signaling pathway, suggesting they might …
NUDCD1 promotes metastasis through inducing EMT and inhibiting apoptosis in colorectal cancer.
Han B, Zhang YY, Xu K, Bai Y, Wan LH, Miao SK, Zhang KX, Zhang HW, Liu Y, Zhou LM. Han B, et al. Am J Cancer Res. 2018 May 1;8(5):810-823. eCollection 2018. Am J Cancer Res. 2018. PMID: 29888104 Free PMC article.
NUDCD1's effects on CRC xenografts of nude mice was also determined. ...In conclusion, NUDCD1 promotes the carcinogenesis and metastasis of CRC through inducing EMT and inhibiting apoptosis, which suggests NUDCD1 be a potential biomarker for CRC....
NUDCD1's effects on CRC xenografts of nude mice was also determined. ...In conclusion, NUDCD1 promotes the carcinogenesis and …
NudCD1 Promotes the Proliferation and Metastasis of Non-Small Cell Lung Cancer Cells through the Activation of IGF1R-ERK1/2.
He B, Xia S, Zhang Z. He B, et al. Pathobiology. 2020;87(4):244-253. doi: 10.1159/000505159. Epub 2020 Jul 7. Pathobiology. 2020. PMID: 32634806 Free article.
Moreover, patients with high expression of NudCD1 had worse prognosis. NudCD1 knockdown was proven to impede the proliferation but facilitate the migration and invasion of cancer cells. ...CONCLUSION: NudCD1 promotes the proliferation and metastasis of NSCLC …
Moreover, patients with high expression of NudCD1 had worse prognosis. NudCD1 knockdown was proven to impede the proliferation …
HDAC7 inhibits cell proliferation via NudCD1/GGH axis in triple-negative breast cancer.
Zhu M, Liu N, Lin J, Wang J, Lai H, Liu Y. Zhu M, et al. Oncol Lett. 2022 Dec 5;25(1):33. doi: 10.3892/ol.2022.13619. eCollection 2023 Jan. Oncol Lett. 2022. PMID: 36589669 Free PMC article.
The results of functional experiments confirmed that HDAC7 negatively modulated GGH and NudCD1 expression. Furthermore, decrease of NudCD1 or GGH inhibited cell proliferation. Notably, the HDAC7-NudCD1/GGH axis was found to be associated with NK cell infiltra …
The results of functional experiments confirmed that HDAC7 negatively modulated GGH and NudCD1 expression. Furthermore, decrease of …
Analysis of NudCD1 and NF-kappabeta in the early detection and course evaluation of renal cancer.
Liu YP, Wei W, He Y, You CJ, Lei CJ. Liu YP, et al. Eur Rev Med Pharmacol Sci. 2020 Dec;24(23):12109-12115. doi: 10.26355/eurrev_202012_23999. Eur Rev Med Pharmacol Sci. 2020. PMID: 33336728 Free article.
NudCD1 and NF-kappabeta were positively correlated. The combined detection improved the diagnostic specificity and sensitivity of renal cancer. ...The combined detection of NudCD1 and NF-kappabeta can improve the early diagnosis of kidney cancer....
NudCD1 and NF-kappabeta were positively correlated. The combined detection improved the diagnostic specificity and sensitivity of ren …
The impact of NudCD1 on renal carcinoma cell proliferation, migration, and invasion.
Wang RJ, Wang N, Cui G, Chen Y, Zhong H, Tang J. Wang RJ, et al. Eur Rev Med Pharmacol Sci. 2018 Feb;22(3):671-677. doi: 10.26355/eurrev_201802_14292. Eur Rev Med Pharmacol Sci. 2018. PMID: 29461594 Free article.
PATIENTS AND METHODS: NudCD1 expression in RCC tissue was tested Western blot. The cellular localization of NudCD1 was detected by immunohistochemistry (IHC). NudCD1 highly expressed RCC cell line was selected. NudCD1 knockdown or overexpression was pe …
PATIENTS AND METHODS: NudCD1 expression in RCC tissue was tested Western blot. The cellular localization of NudCD1 was detecte …
Protein interaction network of alternatively spliced NudCD1 isoforms.
Asselin-Mullen P, Chauvin A, Dubois ML, Drissi R, Lévesque D, Boisvert FM. Asselin-Mullen P, et al. Sci Rep. 2017 Oct 11;7(1):12987. doi: 10.1038/s41598-017-13441-w. Sci Rep. 2017. PMID: 29021621 Free PMC article.
NudCD1, also known as CML66 or OVA66, is a protein initially identified as overexpressed in patients with chronic myelogenous leukemia. The mRNA of NudCD1 is expressed in heart and testis of normal tissues, and is overexpressed in several cancers. ...
NudCD1, also known as CML66 or OVA66, is a protein initially identified as overexpressed in patients with chronic myelogenous leukemi …
29 results