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Did you mean myrup (72 results)?
MyRIP interaction with MyoVa on secretory granules is controlled by the cAMP-PKA pathway.
Brozzi F, Lajus S, Diraison F, Rajatileka S, Hayward K, Regazzi R, Molnár E, Váradi A. Brozzi F, et al. Mol Biol Cell. 2012 Nov;23(22):4444-55. doi: 10.1091/mbc.E12-05-0369. Epub 2012 Sep 19. Mol Biol Cell. 2012. PMID: 22993210 Free PMC article.
Myosin- and Rab-interacting protein (MyRIP), which belongs to the protein kinase A (PKA)-anchoring family, is implicated in hormone secretion. ...In vitro pull-down, coimmunoprecipitation, and colocalization studies revealed that MyRIP does not interact with BR-MyoV …
Myosin- and Rab-interacting protein (MyRIP), which belongs to the protein kinase A (PKA)-anchoring family, is implicated in hormone s …
Interaction between MyRIP and the actin cytoskeleton regulates Weibel-Palade body trafficking and exocytosis.
Conte IL, Hellen N, Bierings R, Mashanov GI, Manneville JB, Kiskin NI, Hannah MJ, Molloy JE, Carter T. Conte IL, et al. J Cell Sci. 2016 Feb 1;129(3):592-603. doi: 10.1242/jcs.178285. Epub 2015 Dec 16. J Cell Sci. 2016. PMID: 26675235 Free PMC article.
To evaluate the specific contribution of MyRIP-actin and MyRIP-MyoVa binding in WPB trafficking and Ca(2+)-driven exocytosis, we used EGFP-MyRIP point mutants with disrupted MyoVa and/or actin binding and high-speed live-cell fluorescence microscopy. We now s …
To evaluate the specific contribution of MyRIP-actin and MyRIP-MyoVa binding in WPB trafficking and Ca(2+)-driven exocytosis, …
Myrip uses distinct domains in the cellular activation of myosin VA and myosin VIIA in melanosome transport.
Ramalho JS, Lopes VS, Tarafder AK, Seabra MC, Hume AN. Ramalho JS, et al. Pigment Cell Melanoma Res. 2009 Aug;22(4):461-73. doi: 10.1111/j.1755-148X.2009.00567.x. Epub 2009 Mar 21. Pigment Cell Melanoma Res. 2009. PMID: 19317802
Here, we addressed the questions of whether Myrip interacts with MyoVa in cells and the molecular basis of cellular activation of MyoVa and MyoVIIa by Myrip. ...Mutagenesis showed that a Myrip-Mlph conserved amphipathic helix (MMAH) is essential for MyoVa int …
Here, we addressed the questions of whether Myrip interacts with MyoVa in cells and the molecular basis of cellular activation of Myo …
MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes.
El-Amraoui A, Schonn JS, Küssel-Andermann P, Blanchard S, Desnos C, Henry JP, Wolfrum U, Darchen F, Petit C. El-Amraoui A, et al. EMBO Rep. 2002 May;3(5):463-70. doi: 10.1093/embo-reports/kvf090. Epub 2002 Apr 18. EMBO Rep. 2002. PMID: 11964381 Free PMC article.
We report on the identification of a novel myosin-VIIa-interacting protein that we have named MyRIP (myosin-VIIa- and Rab-interacting protein), since it also binds to Rab27A in a GTP-dependent manner. In the retinal pigment epithelium cells, MyRIP, myosin VIIa and R …
We report on the identification of a novel myosin-VIIa-interacting protein that we have named MyRIP (myosin-VIIa- and Rab-interacting …
MyRIP anchors protein kinase A to the exocyst complex.
Goehring AS, Pedroja BS, Hinke SA, Langeberg LK, Scott JD. Goehring AS, et al. J Biol Chem. 2007 Nov 9;282(45):33155-67. doi: 10.1074/jbc.M705167200. Epub 2007 Sep 7. J Biol Chem. 2007. PMID: 17827149 Free PMC article.
In this report we demonstrate that the Rab27a GTPase effector protein MyRIP is a member of the AKAP family. The zebrafish homolog of MyRIP (Ze-AKAP2) was initially detected in a two-hybrid screen for AKAPs. ...These data indicate that MyRIP functions as a sca …
In this report we demonstrate that the Rab27a GTPase effector protein MyRIP is a member of the AKAP family. The zebrafish homolog of …
Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane.
Huet S, Fanget I, Jouannot O, Meireles P, Zeiske T, Larochette N, Darchen F, Desnos C. Huet S, et al. J Neurosci. 2012 Feb 15;32(7):2564-77. doi: 10.1523/JNEUROSCI.2724-11.2012. J Neurosci. 2012. PMID: 22396429 Free PMC article.
Myrip also interacts with actin and the exocyst complex, suggesting that it may exert multiple roles in the secretory process. ...Remarkably, while the first two effects of Myrip depend on its ability to recruit myosin Va on SGs, the third is myosin Va independent b …
Myrip also interacts with actin and the exocyst complex, suggesting that it may exert multiple roles in the secretory process. ...Rem …
Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites.
Desnos C, Schonn JS, Huet S, Tran VS, El-Amraoui A, Raposo G, Fanget I, Chapuis C, Ménasché G, de Saint Basile G, Petit C, Cribier S, Henry JP, Darchen F. Desnos C, et al. J Cell Biol. 2003 Nov 10;163(3):559-70. doi: 10.1083/jcb.200302157. J Cell Biol. 2003. PMID: 14610058 Free PMC article.
The GTPase Rab27A interacts with myosin-VIIa and myosin-Va via MyRIP or melanophilin and mediates melanosome binding to actin. Here we show that Rab27A and MyRIP are associated with secretory granules (SGs) in adrenal chromaffin cells and PC12 cells. ...In contrast, …
The GTPase Rab27A interacts with myosin-VIIa and myosin-Va via MyRIP or melanophilin and mediates melanosome binding to actin. Here w …
Involvement of the Rab27 binding protein Slac2c/MyRIP in insulin exocytosis.
Waselle L, Coppola T, Fukuda M, Iezzi M, El-Amraoui A, Petit C, Regazzi R. Waselle L, et al. Mol Biol Cell. 2003 Oct;14(10):4103-13. doi: 10.1091/mbc.e03-01-0022. Epub 2003 Aug 7. Mol Biol Cell. 2003. PMID: 14517322 Free PMC article.
Screening for potential effectors of the GTPase revealed that the Rab27a-binding protein Slac2c/MyRIP is associated with secretory granules of beta-cells. Attenuation of Slac2c/MyRIP expression by RNA interference did not modify basal secretion but severely impaired …
Screening for potential effectors of the GTPase revealed that the Rab27a-binding protein Slac2c/MyRIP is associated with secretory gr …
Analysis of the linkage of MYRIP and MYO7A to melanosomes by RAB27A in retinal pigment epithelial cells.
Klomp AE, Teofilo K, Legacki E, Williams DS. Klomp AE, et al. Cell Motil Cytoskeleton. 2007 Jun;64(6):474-87. doi: 10.1002/cm.20198. Cell Motil Cytoskeleton. 2007. PMID: 17352418
Analyses of mutant mice provide genetic evidence that MYRIP is linked to melanosomes via RAB27A, but show that recruitment of MYRIP to apical RPE is independent of melanosomes and RAB27A. RAB27A and MYRIP also associated with motile small vesicles of unknown …
Analyses of mutant mice provide genetic evidence that MYRIP is linked to melanosomes via RAB27A, but show that recruitment of MYRI …
The ternary Rab27a-Myrip-Myosin VIIa complex regulates melanosome motility in the retinal pigment epithelium.
Lopes VS, Ramalho JS, Owen DM, Karl MO, Strauss O, Futter CE, Seabra MC. Lopes VS, et al. Traffic. 2007 May;8(5):486-99. doi: 10.1111/j.1600-0854.2007.00548.x. Traffic. 2007. PMID: 17451552 Free PMC article.
Here we address the hypothesis that a recently identified Rab27a- and MyoVIIa-interacting protein, Myrip, promotes the formation of a functional tripartite complex. In heterologous cultured cells, all three proteins co-immunoprecipitated following overexpression. Rab27a an …
Here we address the hypothesis that a recently identified Rab27a- and MyoVIIa-interacting protein, Myrip, promotes the formation of a …
46 results