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MPV17L2 is required for ribosome assembly in mitochondria.
Dalla Rosa I, Durigon R, Pearce SF, Rorbach J, Hirst EM, Vidoni S, Reyes A, Brea-Calvo G, Minczuk M, Woellhaf MW, Herrmann JM, Huynen MA, Holt IJ, Spinazzola A. Dalla Rosa I, et al. Nucleic Acids Res. 2014 Jul;42(13):8500-15. doi: 10.1093/nar/gku513. Epub 2014 Jun 19. Nucleic Acids Res. 2014. PMID: 24948607 Free PMC article.
MPV17 is a mitochondrial protein of unknown function, and mutations in MPV17 are associated with mitochondrial deoxyribonucleic acid (DNA) maintenance disorders. Here we investigated its most similar relative, MPV17L2, which is also annotated as a mitochondrial protein. Mi …
MPV17 is a mitochondrial protein of unknown function, and mutations in MPV17 are associated with mitochondrial deoxyribonucleic acid (DNA) m …
Bioengineered miR-34a modulates mitochondrial inner membrane protein 17 like 2 (MPV17L2) expression toward the control of cancer cell mitochondrial functions.
Yi WR, Tu MJ, Yu AX, Lin J, Yu AM. Yi WR, et al. Bioengineered. 2022 May;13(5):12489-12503. doi: 10.1080/21655979.2022.2076399. Bioengineered. 2022. PMID: 35579419 Free PMC article.
Western blot analysis revealed that bioengineered miR-34a-5p effectively reduced MPV17L2 protein outcomes, leading to much lower levels of respiratory chain Complex I activities and intracellular ATP that were determined with specific assay kits. ...These results demonstra …
Western blot analysis revealed that bioengineered miR-34a-5p effectively reduced MPV17L2 protein outcomes, leading to much lower leve …
FT895 Impairs Mitochondrial Function in Malignant Peripheral Nerve Sheath Tumor Cells.
Huang PY, Shih IA, Liao YC, You HL, Lee MJ. Huang PY, et al. Int J Mol Sci. 2023 Dec 24;25(1):277. doi: 10.3390/ijms25010277. Int J Mol Sci. 2023. PMID: 38203448 Free PMC article.
Moreover, the study using CHIP-qPCR analysis revealed a significant reduction in the copy numbers of promoters of the MPV17L2, POLG, TFAM, PINK1, and Parkin genes. The RNA-seq analysis underscored the prominent role of the HIF-1alpha signaling pathway post-FT895 treatment, …
Moreover, the study using CHIP-qPCR analysis revealed a significant reduction in the copy numbers of promoters of the MPV17L2, POLG, …
Effect of vitrification temperature and cryoprotectant concentrations on the mRNA transcriptome of bovine mature oocytes after vitrifying at immature stage.
Zhang F, Zhang ZY, Cai MD, Li XX, Li YH, Lei Y, Yu XL. Zhang F, et al. Theriogenology. 2020 May;148:225-235. doi: 10.1016/j.theriogenology.2019.11.006. Epub 2019 Nov 18. Theriogenology. 2020. PMID: 31761539
Among the DEGs closely related to bovine oocytes, the genes possibly related to VT were ND2, MPV17L2, PIF1, LPIN1, IMP3, BRD1, DCTN3, DERA, ATP7B, NEK5, HVCN1, and MARK2. ...
Among the DEGs closely related to bovine oocytes, the genes possibly related to VT were ND2, MPV17L2, PIF1, LPIN1, IMP3, BRD1, DCTN3, …
A survey of endogenous retrovirus (ERV) sequences in the vicinity of multiple sclerosis (MS)-associated single nucleotide polymorphisms (SNPs).
Brütting C, Emmer A, Kornhuber M, Staege MS. Brütting C, et al. Mol Biol Rep. 2016 Aug;43(8):827-36. doi: 10.1007/s11033-016-4004-0. Epub 2016 May 12. Mol Biol Rep. 2016. PMID: 27169423
We found very high homologies to HERV-K, HCML-ARV, XMRV, Galidia ERV, HERV-H/env62 and XMRV-like mouse endogenous retrovirus mERV-XL. The associated genes (CYP27B1, CD6, CD58, MPV17L2, IL12RB1, CXCR5, PTGER4, TAGAP, TYK2, ICAM3, CD86, GALC, GPR65 as well as the HLA DRB1*15 …
We found very high homologies to HERV-K, HCML-ARV, XMRV, Galidia ERV, HERV-H/env62 and XMRV-like mouse endogenous retrovirus mERV-XL. The as …