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Year Number of Results
2005 4
2006 11
2007 25
2008 41
2009 62
2010 109
2011 157
2012 201
2013 249
2014 260
2015 304
2016 323
2017 329
2018 329
2019 357
2020 379
2021 357
2022 318
2023 260
2024 105

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3,734 results

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Page 1
miR155 deficiency reduces breast tumor burden in the MMTV-PyMT mouse model.
McDonald SJ, Cranford TL, VanderVeen BN, Cardaci TD, Velázquez KT, Enos RT, Chatzistamou I, Fan D, Murphy EA. McDonald SJ, et al. Physiol Genomics. 2022 Nov 1;54(11):433-442. doi: 10.1152/physiolgenomics.00057.2022. Epub 2022 Sep 19. Physiol Genomics. 2022. PMID: 36121133 Free PMC article.
miRNA155 (miR155) has emerged as an important regulator of breast cancer (BrCa) development. ...To study the effects of miR155 in a transgenic model of BrCA, we developed an MMTV-PyMT mouse deficient in miR155 (miR155(-/-) PyMT). miR155(-/-) mic …
miRNA155 (miR155) has emerged as an important regulator of breast cancer (BrCa) development. ...To study the effects of miR155
Mir155 regulates osteogenesis and bone mass phenotype via targeting S1pr1 gene.
Zheng Z, Wu L, Li Z, Tang R, Li H, Huang Y, Wang T, Xu S, Cheng H, Ye Z, Xiao D, Lin X, Wu G, Jaspers RT, Pathak JL. Zheng Z, et al. Elife. 2023 Jan 4;12:e77742. doi: 10.7554/eLife.77742. Elife. 2023. PMID: 36598122 Free PMC article.
Mir155-KO mice showed robust bone regeneration in the ectopic and orthotopic model, but Mir155-Tg mice showed compromised bone regeneration compared with the wild-type mice. ...Moreover, Mir155 knockdown in BMSCs from wild-type mice showed higher osteogenic d
Mir155-KO mice showed robust bone regeneration in the ectopic and orthotopic model, but Mir155-Tg mice showed compromised bone
MiR155 modulates vascular calcification by regulating Akt-FOXO3a signalling and apoptosis in vascular smooth muscle cells.
Li Y, Sun W, Saaoud F, Wang Y, Wang Q, Hodge J, Hui Y, Yin S, Lessner SM, Kong X, Fan D. Li Y, et al. J Cell Mol Med. 2021 Jan;25(1):535-548. doi: 10.1111/jcmm.16107. Epub 2020 Nov 18. J Cell Mol Med. 2021. PMID: 33210462 Free PMC article.
microRNA-155 (miR155) is pro-atherogenic; however, its role in vascular calcification is unknown. ...Wound-healing assay and TUNEL staining showed deletion of miR155 inhibited vascular smooth muscle cell (VSMC) migration and apoptosis. miR155 deficiency atten …
microRNA-155 (miR155) is pro-atherogenic; however, its role in vascular calcification is unknown. ...Wound-healing assay and TUNEL st …
Interleukin-10 control of pre-miR155 maturation involves CELF2.
Yoon JSJ, Wu MK, Zhu TH, Zhao H, Cheung ST, Chamberlain TC, Mui AL. Yoon JSJ, et al. PLoS One. 2020 Apr 23;15(4):e0231639. doi: 10.1371/journal.pone.0231639. eCollection 2020. PLoS One. 2020. PMID: 32324763 Free PMC article.
We previously found that IL10 interfered with the maturation of pre-miR155 to miR155. To understand the mechanism by which IL10 interferes with pre-miR155 maturation we isolated proteins that associate with pre-miR155 in response to IL10 in macrophages …
We previously found that IL10 interfered with the maturation of pre-miR155 to miR155. To understand the mechanism by which IL1 …
MiR155 Disrupts the Intestinal Barrier by Inducing Intestinal Inflammation and Altering the Intestinal Microecology in Severe Acute Pancreatitis.
Yang X, Wan J, Li N, He C, Zhang Y, Ren Y, Li X, Zhu Y, Liu F, Xia L, Lu N. Yang X, et al. Dig Dis Sci. 2022 Jun;67(6):2209-2219. doi: 10.1007/s10620-021-07022-1. Epub 2021 Aug 2. Dig Dis Sci. 2022. PMID: 34341909
AIMS: To investigate the effect of miR155 on severe acute pancreatitis (SAP)-associated intestinal dysfunction and its possible mechanism in a mice model. ...After application of miR155-sponge, imbalance of intestinal flora and destruction of intestinal barrier-rela …
AIMS: To investigate the effect of miR155 on severe acute pancreatitis (SAP)-associated intestinal dysfunction and its possible mecha …
MiR155-5p Inhibits Cell Migration and Oxidative Stress in Vascular Smooth Muscle Cells of Spontaneously Hypertensive Rats.
Wu N, Ye C, Zheng F, Wan GW, Wu LL, Chen Q, Li YH, Kang YM, Zhu GQ. Wu N, et al. Antioxidants (Basel). 2020 Mar 1;9(3):204. doi: 10.3390/antiox9030204. Antioxidants (Basel). 2020. PMID: 32121598 Free PMC article.
Wound healing assay and Boyden chamber assay were used to evaluate VSMC migration. A miR155-5p mimic inhibited, and a miR155-5p inhibitor promoted the migration of VSMC of SHR but had no significant effect on the migration of VSMC of WKY. ...However, miR155-5 …
Wound healing assay and Boyden chamber assay were used to evaluate VSMC migration. A miR155-5p mimic inhibited, and a miR155-5 …
Host miR155 promotes tumor growth through a myeloid-derived suppressor cell-dependent mechanism.
Chen S, Wang L, Fan J, Ye C, Dominguez D, Zhang Y, Curiel TJ, Fang D, Kuzel TM, Zhang B. Chen S, et al. Cancer Res. 2015 Feb 1;75(3):519-31. doi: 10.1158/0008-5472.CAN-14-2331. Epub 2014 Dec 10. Cancer Res. 2015. PMID: 25502838 Free PMC article.
However, we report here that genetic ablation of miR155 renders mice resistant to chemical carcinogenesis and the growth of several transplanted tumors, suggesting that miR155 functions in immunosuppression and tumor promotion. Host miR155 deficiency promoted …
However, we report here that genetic ablation of miR155 renders mice resistant to chemical carcinogenesis and the growth of several t …
miR155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice.
Velázquez KT, Enos RT, Carson MS, Cranford TL, Bader JE, Sougiannis AT, Pritchett C, Fan D, Carson JA, Murphy EA. Velázquez KT, et al. Physiol Rep. 2017 Sep;5(18):e13412. doi: 10.14814/phy2.13412. Physiol Rep. 2017. PMID: 28947593 Free PMC article.
However, miR155(-/-) HFD displayed exacerbated adipose tissue fibrosis and decreased PPAR-gamma protein content. The loss of miR155 did not affect adipose tissue inflammation or glucose metabolism. ...
However, miR155(-/-) HFD displayed exacerbated adipose tissue fibrosis and decreased PPAR-gamma protein content. The loss of miR15
Activated CLL cells regulate IL-17F-producing Th17 cells in miR155-dependent and outcome-specific manners.
Jung B, Ferrer G, Chiu PY, Aslam R, Ng A, Palacios F, Wysota M, Cardillo M, Kolitz JE, Allen SL, Barrientos JC, Rai KR, Chiorazzi N, Sherry B. Jung B, et al. JCI Insight. 2022 Jun 22;7(12):e158243. doi: 10.1172/jci.insight.158243. JCI Insight. 2022. PMID: 35511436 Free PMC article.
Moreover, patients with CLL have elevated levels of circulating IL-17A+ and IL-17F+ CD4+ T (Th17) cells, with higher numbers of IL-17A+ Th17 cells correlating with better outcomes. We report that CLL Th17 cells expressed more miR155, a Th17-differentiation regulator, than …
Moreover, patients with CLL have elevated levels of circulating IL-17A+ and IL-17F+ CD4+ T (Th17) cells, with higher numbers of IL-17A+ Th17 …
[Targeting miR155 restores chemotherapy sensitivity in drug-resistant myeloma cell-line RPMI8226/DOX cells].
Xiao CR, Hong XL, Hu JS, Chen YM, Lu QY. Xiao CR, et al. Zhonghua Xue Ye Xue Za Zhi. 2017 Jan 14;38(1):55-59. doi: 10.3760/cma.j.issn.0253-2727.2017.01.012. Zhonghua Xue Ye Xue Za Zhi. 2017. PMID: 28219227 Free PMC article. Chinese.
Objective: To explore the mechanism of abnormal expression of microRNA155 (miR155) in myeloma drug-resistance to probe the possibility of inhibiting miR155 expression to restore chemotherapy sensitivity and its molecular mechanism in drug-resistant myeloma cells. .. …
Objective: To explore the mechanism of abnormal expression of microRNA155 (miR155) in myeloma drug-resistance to probe the possibilit …
3,734 results