Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2009 1
2011 1
2013 1
2014 3
2015 2
2018 1
2022 3
2023 3
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

16 results

Results by year

Filters applied: . Clear all
Page 1
IQUB deficiency causes male infertility by affecting the activity of p-ERK1/2/RSPH3.
Zhang Z, Zhou H, Deng X, Zhang R, Qu R, Mu J, Liu R, Zeng Y, Chen B, Wang L, Sang Q, Bao S. Zhang Z, et al. Hum Reprod. 2023 Jan 5;38(1):168-179. doi: 10.1093/humrep/deac244. Hum Reprod. 2023. PMID: 36355624
Iqub KO and KI mice mimicked the infertility phenotype and confirmed IQUB to be the pathogenetic gene. ...Therefore, this study lacks direct in vivo proof to confirm the effect of the variant on IQUB protein level. WIDER IMPLICATIONS OF THE FINDINGS: Our resu …
Iqub KO and KI mice mimicked the infertility phenotype and confirmed IQUB to be the pathogenetic gene. ...Therefore, this stud …
Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella.
Zhang X, Xiao Z, Zhang J, Xu C, Liu S, Cheng L, Zhou S, Zhao S, Zhang Y, Wu J, Wang Y, Liu M. Zhang X, et al. Cell Rep. 2022 Nov 22;41(8):111683. doi: 10.1016/j.celrep.2022.111683. Cell Rep. 2022. PMID: 36417862 Free article.
Here, we introduce a mouse model that lacked the entire RS1 in sperm flagella, due to the deletion of Iqub, while the tracheal cilia possessed intact triple RSs. Furthermore, the absence of IQUB only resulted in male infertility, owing to the sperm motility defect. …
Here, we introduce a mouse model that lacked the entire RS1 in sperm flagella, due to the deletion of Iqub, while the tracheal cilia …
Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3beta/beta-catenin signaling pathway in breast cancer.
Li K, Ma YB, Zhang Z, Tian YH, Xu XL, He YQ, Xu L, Gao Y, Pan WT, Song WJ, He X, Wei L. Li K, et al. Cancer Med. 2018 Aug;7(8):3875-3888. doi: 10.1002/cam4.1568. Epub 2018 Jul 2. Cancer Med. 2018. PMID: 29968965 Free PMC article.
However, there were no studies on the mechanism of IQUB in tumorigenesis. Further study showed that IQUB expression was significantly increased in breast cancer, which had a significantly positive correlation with pathological differentiation of breast cancer by tis …
However, there were no studies on the mechanism of IQUB in tumorigenesis. Further study showed that IQUB expression was signif …
[Preparation and application of rabbit polyclonal antibody against mouse IQ and ubiquitin-like domain-containing protein (IQUB)].
Yuan L, Xu W, Ge T, Zhou H, Yang L, Yang F, Niu C, Zheng Y. Yuan L, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2023 Sep;39(9):846-851. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2023. PMID: 37732581 Chinese.
Results pET-30a-IQUB recombinant plasmid was constructed, and protein expression of IQUB was induced successfully with IPTG. The titer of IQUB polyclonal antibody reached 1:1 000 000. The antibody specifically recognized the endogenous IQUB protein of …
Results pET-30a-IQUB recombinant plasmid was constructed, and protein expression of IQUB was induced successfully with IPTG. T …
Combining bioinformatics, network pharmacology and artificial intelligence to predict the mechanism of celastrol in the treatment of type 2 diabetes.
Wu M, Zhang Y. Wu M, et al. Front Endocrinol (Lausanne). 2022 Oct 19;13:1030278. doi: 10.3389/fendo.2022.1030278. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36339449 Free PMC article.
A total of 228 target genes were annotated by pharmacophore target analysis, and the therapeutic targets were identified, including S100A11, RBP3, HBB, BMP7 and IQUB, and 9 therapeutic signaling pathways were obtained by an intersectional set. ...
A total of 228 target genes were annotated by pharmacophore target analysis, and the therapeutic targets were identified, including S100A11, …
Whole genome and transcriptome sequencing of matched primary and peritoneal metastatic gastric carcinoma.
Zhang J, Huang JY, Chen YN, Yuan F, Zhang H, Yan FH, Wang MJ, Wang G, Su M, Lu G, Huang Y, Dai H, Ji J, Zhang J, Zhang JN, Jiang YN, Chen SJ, Zhu ZG, Yu YY. Zhang J, et al. Sci Rep. 2015 Sep 2;5:13750. doi: 10.1038/srep13750. Sci Rep. 2015. PMID: 26330360 Free PMC article.
We identified 27 mutated genes, of which 19 genes are reported in COSMIC database (ZNF208, CRNN, ATXN3, DCTN1, RP1L1, PRB4, PRB1, MUC4, HS6ST3, MUC17, JAM2, ITGAD, IREB2, IQUB, CORO1B, CCDC121, AKAP2, ACAN and ACADL), and eight genes have not previously been described in g …
We identified 27 mutated genes, of which 19 genes are reported in COSMIC database (ZNF208, CRNN, ATXN3, DCTN1, RP1L1, PRB4, PRB1, MUC4, HS6S …
Functional characterization of putative cilia genes by high-content analysis.
Lai CK, Gupta N, Wen X, Rangell L, Chih B, Peterson AS, Bazan JF, Li L, Scales SJ. Lai CK, et al. Mol Biol Cell. 2011 Apr;22(7):1104-19. doi: 10.1091/mbc.E10-07-0596. Epub 2011 Feb 2. Mol Biol Cell. 2011. PMID: 21289087 Free PMC article.
Validated hits include Ssa2 and mC21orf2 with ciliation defects; Ift46 with short cilia; Ptpdc1 and Iqub with elongated cilia; and Arl3, Nme7, and Ssna1 with distinct ciliary transport but not length defects. ...
Validated hits include Ssa2 and mC21orf2 with ciliation defects; Ift46 with short cilia; Ptpdc1 and Iqub with elongated cilia; and Ar …
Transcriptome-wide profile of 1α,25 dihydroxyvitamin D3 in HTR-8/SVneo cells.
Luo J, Tang L, Zhang R, Lv M, You D, Yuan Q. Luo J, et al. J Obstet Gynaecol Res. 2023 Aug;49(8):2093-2101. doi: 10.1111/jog.15685. Epub 2023 Jun 5. J Obstet Gynaecol Res. 2023. PMID: 37277920
TCF24, EIF3CL, ABCD2, EPHA7, CRLF1, and SECTM1 were specific genes at physiological concentration. Similarly, SPDYE1, IQUB, IL18R1, and ZNF713 were considered as specific genes at supraphysiological concentration. ...
TCF24, EIF3CL, ABCD2, EPHA7, CRLF1, and SECTM1 were specific genes at physiological concentration. Similarly, SPDYE1, IQUB, IL18R1, a …
Mechanisms underlying morphological and functional changes of cilia in fibroblasts derived from patients bearing ARL3T31A and ARL3T31A/C118F mutations.
Zhang X, Yao S, Zhang L, Yang L, Yang M, Guo Q, Li Y, Wang Z, Lei B, Jin X. Zhang X, et al. FASEB J. 2024 Mar 15;38(5):e23519. doi: 10.1096/fj.202301906R. FASEB J. 2024. PMID: 38457249
Similar changes were observed in the proteomic results in ARPE-19 cells. Core regulated genes including IQUB, UNC13D, RAB3IP, and GRIP1 were specifically downregulated in the ARL3(T31A/C118F) group, and expressions of IQUB, NPM2, and SLC38A4 were further validated. …
Similar changes were observed in the proteomic results in ARPE-19 cells. Core regulated genes including IQUB, UNC13D, RAB3IP, and GRI …
Does non-farm employment increase rural households' consumption in western Ethiopia? Empirical evidence from the horo guduru wollega zone.
Tesgera WD, Beyene AB, Wakjira TK. Tesgera WD, et al. Heliyon. 2024 Feb 16;10(7):e26449. doi: 10.1016/j.heliyon.2024.e26449. eCollection 2024 Apr 15. Heliyon. 2024. PMID: 38617956 Free PMC article.
These factors include education, access to credit, distance to market, TLU (Tropical Livestock Unit), membership in "iqub" (a social financial system), health status, non-farm training, and gender. ...The study emphasized the significance of recognizing the impact of suppo …
These factors include education, access to credit, distance to market, TLU (Tropical Livestock Unit), membership in "iqub" (a social …
16 results