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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1990 3
1991 3
1992 2
1993 4
1994 3
1995 5
1996 5
1997 1
1998 6
1999 4
2000 1
2001 7
2002 6
2003 4
2004 8
2005 13
2006 2
2007 10
2008 10
2009 12
2010 13
2011 25
2012 19
2013 23
2014 29
2015 22
2016 22
2017 37
2018 21
2019 40
2020 42
2021 53
2022 53
2023 49
2024 18

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503 results

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Page 1
H3K27 acetylation activated-COL6A1 promotes osteosarcoma lung metastasis by repressing STAT1 and activating pulmonary cancer-associated fibroblasts.
Zhang Y, Liu Z, Yang X, Lu W, Chen Y, Lin Y, Wang J, Lin S, Yun JP. Zhang Y, et al. Theranostics. 2021 Jan 1;11(3):1473-1492. doi: 10.7150/thno.51245. eCollection 2021. Theranostics. 2021. PMID: 33391546 Free PMC article.
Background: Collagen type VI alpha 1 (COL6A1) has been found to be dysregulated in several human malignancies. However, the role of COL6A1 in osteosarcoma (OS) progression remains largely unclear. Here, we aimed to explore the clinical significance and biological in …
Background: Collagen type VI alpha 1 (COL6A1) has been found to be dysregulated in several human malignancies. However, the role of …
Collagen VI in the Musculoskeletal System.
Di Martino A, Cescon M, D'Agostino C, Schilardi F, Sabatelli P, Merlini L, Faldini C. Di Martino A, et al. Int J Mol Sci. 2023 Mar 7;24(6):5095. doi: 10.3390/ijms24065095. Int J Mol Sci. 2023. PMID: 36982167 Free PMC article. Review.
Collagen VI exerts several functions in the tissues in which it is expressed, including mechanical roles, cytoprotective functions with the inhibition of apoptosis and oxidative damage, and the promotion of tumor growth and progression by the regulation of cell differentiation an …
Collagen VI exerts several functions in the tissues in which it is expressed, including mechanical roles, cytoprotective functions with the …
Exon-Skipping for a Pathogenic COL6A1 Variant in Ullrich Congenital Muscular Dystrophy.
Aguti S, Guirguis F, Bönnemann C, Muntoni F, Bolduc V, Zhou H. Aguti S, et al. Methods Mol Biol. 2023;2587:387-407. doi: 10.1007/978-1-0716-2772-3_20. Methods Mol Biol. 2023. PMID: 36401040
This erroneous PE insertion is caused by a deep-intronic variant located within intron 11 of COL6A1 (c.930+189 C>T). Here, we describe the detailed protocols and workflow that our labs have used to assess the efficacy of ASOs to skip this PE in vitro. ...
This erroneous PE insertion is caused by a deep-intronic variant located within intron 11 of COL6A1 (c.930+189 C>T). Here, we desc …
High expression of COL6A1 predicts poor prognosis and response to immunotherapy in bladder cancer.
Zhang X, Liu J, Yang X, Jiao W, Shen C, Zhao X, Wang Y. Zhang X, et al. Cell Cycle. 2023 Mar;22(5):610-618. doi: 10.1080/15384101.2022.2154551. Epub 2022 Dec 6. Cell Cycle. 2023. PMID: 36474424 Free PMC article.
Immunohistochemistry was used to detect the protein expression of hub gene-COL6A1 in BC patients. Using bioinformatics analysis from The Cancer Genome Atlas (TCGA) database and proteomic analysis from our BC cohort, we constructed and validated an effective prognostic pred …
Immunohistochemistry was used to detect the protein expression of hub gene-COL6A1 in BC patients. Using bioinformatics analysis from …
Col6a1(+)/CD201(+) mesenchymal cells regulate intestinal morphogenesis and homeostasis.
Melissari MT, Henriques A, Tzaferis C, Prados A, Sarris ME, Chalkidi N, Mavroeidi D, Chouvardas P, Grammenoudi S, Kollias G, Koliaraki V. Melissari MT, et al. Cell Mol Life Sci. 2021 Dec 15;79(1):1. doi: 10.1007/s00018-021-04071-7. Cell Mol Life Sci. 2021. PMID: 34910257
Developmental studies revealed that the Col6a1(Cre) mouse also targets mesenchymal aggregates that are crucial for intestinal morphogenesis and patterning, suggesting an ontogenic relationship between them and homeostatic PDGFRalpha(hi) telocytes. Cell depletion experiment …
Developmental studies revealed that the Col6a1(Cre) mouse also targets mesenchymal aggregates that are crucial for intestinal morphog …
COL6A1 promotes metastasis and predicts poor prognosis in patients with pancreatic cancer.
Owusu-Ansah KG, Song G, Chen R, Edoo MIA, Li J, Chen B, Wu J, Zhou L, Xie H, Jiang D, Zheng S. Owusu-Ansah KG, et al. Int J Oncol. 2019 Aug;55(2):391-404. doi: 10.3892/ijo.2019.4825. Epub 2019 Jun 14. Int J Oncol. 2019. PMID: 31268154 Free PMC article.
The median OS observed for COL6A1+ and COL6A1- patients was found to be 84 and 147 months (P=0.021), respectively. Of note, we identified that COL6A1 expression in tissue samples was associated with significantly reduced OS (P=0.001), demonstrating that CO …
The median OS observed for COL6A1+ and COL6A1- patients was found to be 84 and 147 months (P=0.021), respectively. Of note, we …
A 20-year Clinical and Genetic Neuromuscular Cohort Analysis in Lebanon: An International Effort.
Megarbane A, Bizzari S, Deepthi A, Sabbagh S, Mansour H, Chouery E, Hmaimess G, Jabbour R, Mehawej C, Alame S, Hani A, Hasbini D, Ghanem I, Koussa S, Al-Ali MT, Obeid M, Talea DB, Lefranc G, Lévy N, Leturcq F, El Hayek S, Delague V, Urtizberea JA. Megarbane A, et al. J Neuromuscul Dis. 2022;9(1):193-210. doi: 10.3233/JND-210652. J Neuromuscul Dis. 2022. PMID: 34602496 Free PMC article.
Activation and Functions of Col6a1+ Fibroblasts in Colitis-Associated Cancer.
Chalkidi N, Melissari MT, Henriques A, Stavropoulou A, Kollias G, Koliaraki V. Chalkidi N, et al. Int J Mol Sci. 2023 Dec 21;25(1):148. doi: 10.3390/ijms25010148. Int J Mol Sci. 2023. PMID: 38203319 Free PMC article.
In response to cytokines, such as interleukin 1 (IL-1) and tumor necrosis factor (TNF), as well as microbial products, CAFs acquire an immunoregulatory phenotype, but its specificity and pathophysiological significance in individual CAF subsets is yet to be determined. In this st …
In response to cytokines, such as interleukin 1 (IL-1) and tumor necrosis factor (TNF), as well as microbial products, CAFs acquire an immun …
Exome sequencing and characterization of 49,960 individuals in the UK Biobank.
Van Hout CV, Tachmazidou I, Backman JD, Hoffman JD, Liu D, Pandey AK, Gonzaga-Jauregui C, Khalid S, Ye B, Banerjee N, Li AH, O'Dushlaine C, Marcketta A, Staples J, Schurmann C, Hawes A, Maxwell E, Barnard L, Lopez A, Penn J, Habegger L, Blumenfeld AL, Bai X, O'Keeffe S, Yadav A, Praveen K, Jones M, Salerno WJ, Chung WK, Surakka I, Willer CJ, Hveem K, Leader JB, Carey DJ, Ledbetter DH; Geisinger-Regeneron DiscovEHR Collaboration; Cardon L, Yancopoulos GD, Economides A, Coppola G, Shuldiner AR, Balasubramanian S, Cantor M; Regeneron Genetics Center; Nelson MR, Whittaker J, Reid JG, Marchini J, Overton JD, Scott RA, Abecasis GR, Yerges-Armstrong L, Baras A. Van Hout CV, et al. Nature. 2020 Oct;586(7831):749-756. doi: 10.1038/s41586-020-2853-0. Epub 2020 Oct 21. Nature. 2020. PMID: 33087929 Free PMC article.
In addition to replicating established associations, we found novel LOF variants with large effects on disease traits, including PIEZO1 on varicose veins, COL6A1 on corneal resistance, MEPE on bone density, and IQGAP2 and GMPR on blood cell traits. ...
In addition to replicating established associations, we found novel LOF variants with large effects on disease traits, including PIEZO1 on v …
A novel de novo COL6A1 mutation emphasizes the role of intron 14 donor splice site defects as a cause of moderate-progressive form of ColVI myopathy - a case report and review of the genotype-phenotype correlation.
Koppolu AA, Madej-Pilarczyk A, Rydzanicz M, Kosińska J, Gasperowicz P, Dorszewska J, Kozubski W, Steinborn B, Kochański AM, Płoski R. Koppolu AA, et al. Folia Neuropathol. 2017;55(3):214-220. doi: 10.5114/fn.2017.70486. Folia Neuropathol. 2017. PMID: 28984114 Free article. Review.
Here we report a novel de novo c.1056+3A>C substitution in intron 14 of the COL6A1 gene encoding alpha-chains of collagen VI in a 13-year-old girl suffering from collagen VI (ColVI) myopathy. ...Analysis of the literature indicates that the donor splice site of COL6A …
Here we report a novel de novo c.1056+3A>C substitution in intron 14 of the COL6A1 gene encoding alpha-chains of collagen VI in a …
503 results