Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2015 1
2016 1
2019 2
2020 2
2021 3
2022 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

6 results

Results by year

Filters applied: . Clear all
Page 1
CARMIL3 is important for cell migration and morphogenesis during early development in zebrafish.
Stark BC, Gao Y, Sepich DS, Belk L, Culver MA, Hu B, Mekel M, Ferris W, Shin J, Solnica-Krezel L, Lin F, Cooper JA. Stark BC, et al. Dev Biol. 2022 Jan;481:148-159. doi: 10.1016/j.ydbio.2021.09.008. Epub 2021 Sep 30. Dev Biol. 2022. PMID: 34599906 Free PMC article.
CP activity can be regulated by capping-protein-interacting (CPI) motif proteins, including CARMIL (capping protein Arp2/3 myosin-I linker) family proteins. Previous studies of CARMIL3, one of the three highly conserved CARMIL genes in vertebrates, have largely been limite …
CP activity can be regulated by capping-protein-interacting (CPI) motif proteins, including CARMIL (capping protein Arp2/3 myosin-I linker) …
Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.
Wang H, Wang C, Peng G, Yu D, Cui XG, Sun YH, Ma X. Wang H, et al. Mol Cancer Res. 2020 Feb;18(2):240-252. doi: 10.1158/1541-7786.MCR-19-0722. Epub 2019 Nov 6. Mol Cancer Res. 2020. PMID: 31694931
Moreover, molecular pathway enrichment analysis reveals that lack of CARMIL3 leads to loss of cell adhesions and low CARMIL3 expression in breast cancer patient specimens is implicated in epithelial-mesenchymal transition. ...IMPLICATIONS: This study uncovers CAR …
Moreover, molecular pathway enrichment analysis reveals that lack of CARMIL3 leads to loss of cell adhesions and low CARMIL3 e …
Capping Protein Regulator and Myosin 1 Linker 3 (CARMIL3) as a Molecular Signature of Ischemic Neurons in the DWI-T2 Mismatch Areas After Stroke.
Yeh SJ, Hsu PH, Yeh TY, Yang WK, Chang KP, Chiang CS, Tang SC, Tsai LK, Jeng JS, Hsieh ST. Yeh SJ, et al. Front Mol Neurosci. 2021 Dec 16;14:754762. doi: 10.3389/fnmol.2021.754762. eCollection 2021. Front Mol Neurosci. 2021. PMID: 34975397 Free PMC article.
The increased expression of CARMIL3 was validated in a cell model of cortical neurons after OGD and in infarcted human brain tissues. In conclusion, this study shows that the mismatch and T2(+) areas within 4.5 h after ischemia are characterized by upregulated expression o …
The increased expression of CARMIL3 was validated in a cell model of cortical neurons after OGD and in infarcted human brain tissues. …
Capping protein regulator and myosin 1 linker 3 regulates transcription of key cytokines in activated phagocytic cells.
Zhao N, Dong W, Kim H, Moallemian R, Lv J, Wang H, Zheng H, Wei F, Ma X. Zhao N, et al. Cell Signal. 2021 Feb;78:109848. doi: 10.1016/j.cellsig.2020.109848. Epub 2020 Nov 24. Cell Signal. 2021. PMID: 33246003
CARMIL3-deficient macrophages expressed strongly abrogated levels of interleukin (IL)-6, TNF-alpha, IL-1beta and IL-23 in response to LPS, whereas IL-10 expression was enhanced. ...This study uncovers a crucial role of CARMIL3 in impacting the balance between inflam …
CARMIL3-deficient macrophages expressed strongly abrogated levels of interleukin (IL)-6, TNF-alpha, IL-1beta and IL-23 in response to …
In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation.
Spence EF, Dube S, Uezu A, Locke M, Soderblom EJ, Soderling SH. Spence EF, et al. Nat Commun. 2019 Jan 23;10(1):386. doi: 10.1038/s41467-019-08288-w. Nat Commun. 2019. PMID: 30674877 Free PMC article.
This approach uncovered sixty proteins, including a previously uncharacterized protein, CARMIL3, which interacts in vivo with the synaptic cytoskeletal regulator proteins SrGAP3 (or WRP) and actin capping protein. Using new CRISPR-based approaches, we validate that endogen …
This approach uncovered sixty proteins, including a previously uncharacterized protein, CARMIL3, which interacts in vivo with the syn …
Cell Migration and Invadopodia Formation Require a Membrane-binding Domain of CARMIL2.
Lanier MH, McConnell P, Cooper JA. Lanier MH, et al. J Biol Chem. 2016 Jan 15;291(3):1076-91. doi: 10.1074/jbc.M115.676882. Epub 2015 Nov 17. J Biol Chem. 2016. PMID: 26578515 Free PMC article.
Most important, we find that the membrane-binding domain is necessary for CARMIL2 to function in cells, based on rescue expression with a set of biochemically defined mutants. CARMIL1 and CARMIL3 contain similar membrane-binding domains, based on sequence analysis and on e …
Most important, we find that the membrane-binding domain is necessary for CARMIL2 to function in cells, based on rescue expression with a se …