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Page 1
Identification of genetic loci jointly influencing COVID-19 and coronary heart diseases.
Wang S, Peng H, Chen F, Liu C, Zheng Q, Wang M, Wang J, Yu H, Xue E, Chen X, Wang X, Fan M, Qin X, Wu Y, Li J, Ye Y, Chen D, Hu Y, Wu T. Wang S, et al. Hum Genomics. 2023 Nov 14;17(1):101. doi: 10.1186/s40246-023-00547-8. Hum Genomics. 2023. PMID: 37964352 Free PMC article.
The SNP (rs10490770) located near LZTFL1 suggested direct causality (SNPs COVID-19 CHD), and SNPs in ABO (rs579459, rs495828), ILRUN(rs2744961), and CACFD1(rs4962153, rs3094379) may simultaneously influence COVID-19 severity and CHD risks. INTERPRETATION: Five SNPs located …
The SNP (rs10490770) located near LZTFL1 suggested direct causality (SNPs COVID-19 CHD), and SNPs in ABO (rs579459, rs495828), ILRUN(rs27449 …
Genome-wide meta-analysis associates GPSM1 with type 2 diabetes, a plausible gene involved in skeletal muscle function.
Ding Q, Tan ALM, Parra EJ, Cruz M, Sim X, Teo YY, Long J, Alsafar H, Petretto E, Tai ES, Chen H. Ding Q, et al. J Hum Genet. 2020 Apr;65(4):411-420. doi: 10.1038/s10038-019-0720-3. Epub 2020 Jan 21. J Hum Genet. 2020. PMID: 31959871
Another independent Asian cohort showed that rs28539249 is associated with the skeletal muscle expression of CACFD1, GTF3C5, SARDH, and FAM163B genes, which are functionally enriched for endoplasmic reticulum stress (ERS) and unfolded protein response (UPR) pathways. ...
Another independent Asian cohort showed that rs28539249 is associated with the skeletal muscle expression of CACFD1, GTF3C5, SARDH, a …
The effects of Qi Teng Xiao Zhuo granules, traditional Chinese medicine, on the expression of genes in chronic glomerulonephritis rats.
Gao JR, Qin XJ, Jiang H, Wang T, Song JM, Xu SZ. Gao JR, et al. J Ethnopharmacol. 2016 Dec 4;193:140-149. doi: 10.1016/j.jep.2016.08.011. Epub 2016 Aug 4. J Ethnopharmacol. 2016. PMID: 27497640
RESULTS: Microarray gene expression analysis showed that Pnoc, Cacfd1, Fos, Igll1, Lcn2, and Syk were among the most downregulated genes in the Qi Teng Xiao Zhuo granule group compared with the adriamycin treated group, whereas Cyp2c7, Hsd3b6, Acsm5, and Ugt2b15 were signi …
RESULTS: Microarray gene expression analysis showed that Pnoc, Cacfd1, Fos, Igll1, Lcn2, and Syk were among the most downregulated ge …
Flower isoforms promote competitive growth in cancer.
Madan E, Pelham CJ, Nagane M, Parker TM, Canas-Marques R, Fazio K, Shaik K, Yuan Y, Henriques V, Galzerano A, Yamashita T, Pinto MAF, Palma AM, Camacho D, Vieira A, Soldini D, Nakshatri H, Post SR, Rhiner C, Yamashita H, Accardi D, Hansen LA, Carvalho C, Beltran AL, Kuppusamy P, Gogna R, Moreno E. Madan E, et al. Nature. 2019 Aug;572(7768):260-264. doi: 10.1038/s41586-019-1429-3. Epub 2019 Jul 24. Nature. 2019. PMID: 31341286
Reactive astrocytes in ALS display diminished intron retention.
Ziff OJ, Taha DM, Crerar H, Clarke BE, Chakrabarti AM, Kelly G, Neeves J, Tyzack GE, Luscombe NM, Patani R. Ziff OJ, et al. Nucleic Acids Res. 2021 Apr 6;49(6):3168-3184. doi: 10.1093/nar/gkab115. Nucleic Acids Res. 2021. PMID: 33684213 Free PMC article.