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Did you mean bgla (131 results)?
Circulating Extracellular Vesicle-Propagated microRNA Signature as a Vascular Calcification Factor in Chronic Kidney Disease.
Koide T, Mandai S, Kitaoka R, Matsuki H, Chiga M, Yamamoto K, Yoshioka K, Yagi Y, Suzuki S, Fujiki T, Ando F, Mori T, Susa K, Iimori S, Naito S, Sohara E, Rai T, Yokota T, Uchida S. Koide T, et al. Circ Res. 2023 Feb 17;132(4):415-431. doi: 10.1161/CIRCRESAHA.122.321939. Epub 2023 Jan 26. Circ Res. 2023. PMID: 36700539 Free article.
Cultures of A10 embryonic rat VSMCs showed increased calcification and transcription of osterix (Sp7), osteocalcin (Bglap), and osteopontin (Spp1) when treated with rat CKD serum. sEVs, but not sEV-depleted serum, accelerated calcification in VSMCs. ...
Cultures of A10 embryonic rat VSMCs showed increased calcification and transcription of osterix (Sp7), osteocalcin (Bglap), and osteo …
Whole Aspect of Runx2 Functions in Skeletal Development.
Komori T. Komori T. Int J Mol Sci. 2022 May 21;23(10):5776. doi: 10.3390/ijms23105776. Int J Mol Sci. 2022. PMID: 35628587 Free PMC article. Review.
In immature osteoblasts, Runx2 regulates the expression of bone matrix protein genes, including Col1a1, Col1a2, Spp1, Ibsp, and bone gamma carboxyglutamate protein (Bglap)/Bglap2, and induces osteoblast maturation. Osteocalcin (Bglap/Bglap2) is required for the alig …
In immature osteoblasts, Runx2 regulates the expression of bone matrix protein genes, including Col1a1, Col1a2, Spp1, Ibsp, and bone gamma c …
NAP1L2 drives mesenchymal stem cell senescence and suppresses osteogenic differentiation.
Hu M, Xing L, Zhang L, Liu F, Wang S, Xie Y, Wang J, Jiang H, Guo J, Li X, Wang J, Sui L, Li C, Liu D, Liu Z. Hu M, et al. Aging Cell. 2022 Feb;21(2):e13551. doi: 10.1111/acel.13551. Epub 2022 Jan 15. Aging Cell. 2022. PMID: 35032339 Free PMC article.
Mechanistic studies revealed that NAP1L2, a histone chaperone, recruited SIRT1 to deacetylate H3K14ac on promoters of osteogenic genes such as Runx2, Sp7, and Bglap and suppressed the osteogenic differentiation of BMSCs. Importantly, molecular docking analysis showed a pos …
Mechanistic studies revealed that NAP1L2, a histone chaperone, recruited SIRT1 to deacetylate H3K14ac on promoters of osteogenic genes such …
Osteocalcin: A Multifaceted Bone-Derived Hormone.
Karsenty G. Karsenty G. Annu Rev Nutr. 2023 Aug 21;43:55-71. doi: 10.1146/annurev-nutr-061121-091348. Annu Rev Nutr. 2023. PMID: 37603430 Free PMC article. Review.
BGLAP is expressed in pancreatic cancer cells and increases their growth and invasion.
Kayed H, Bekasi S, Keleg S, Michalski CW, Giese T, Friess H, Kleeff J. Kayed H, et al. Mol Cancer. 2007 Dec 28;6:83. doi: 10.1186/1476-4598-6-83. Mol Cancer. 2007. PMID: 18163903 Free PMC article.
TNFalpha reduced BGLAP mRNA and protein expression levels in pancreatic cancer cell lines. In addition, BGLAP silencing led to reduction of both cell growth and invasion in those cells. ...
TNFalpha reduced BGLAP mRNA and protein expression levels in pancreatic cancer cell lines. In addition, BGLAP silencing led to …
Sensitive detection of Cre-mediated recombination using droplet digital PCR reveals Tg(BGLAP-Cre) and Tg(DMP1-Cre) are active in multiple non-skeletal tissues.
Dasgupta K, Lessard S, Hann S, Fowler ME, Robling AG, Warman ML. Dasgupta K, et al. Bone. 2021 Jan;142:115674. doi: 10.1016/j.bone.2020.115674. Epub 2020 Oct 6. Bone. 2021. PMID: 33031974
We observed Tg(BGLAP-Cre);Pik3ca(H1047R/+) offspring were born at the expected Mendelian frequency. ...Assuming that Cre-activity outside of the skeletal system accounted for the difference in phenotype between Tg(BGLAP-Cre);Pik3ca(H1047R/+) and Tg(DMP1-Cre);Pik3ca( …
We observed Tg(BGLAP-Cre);Pik3ca(H1047R/+) offspring were born at the expected Mendelian frequency. ...Assuming that Cre-activity out …
Garlic extract enhances bioceramic bone scaffolds through upregulating ALP & BGLAP expression in hMSC-monocyte co-culture.
Bose S, Robertson SF, Vu AA. Bose S, et al. Biomater Adv. 2023 Nov;154:213622. doi: 10.1016/j.bioadv.2023.213622. Epub 2023 Sep 9. Biomater Adv. 2023. PMID: 37742556
Osteoblastic gene markers alkaline phosphatase (ALP) and osteocalcin (BGLAP), are respectively upregulated by 3-fold and 1.6-fold by day 14. ...
Osteoblastic gene markers alkaline phosphatase (ALP) and osteocalcin (BGLAP), are respectively upregulated by 3-fold and 1.6-fold by …
A matter of origin - identification of SEMA3A, BGLAP, SPP1 and PHEX as distinctive molecular features between bone site-specific human osteoblasts on transcription level.
Zhang W, Rau S, Kotzagiorgis K, Rothweiler R, Nahles S, Gottwald E, Rolauffs B, Steinberg T, Nelson K, Altmann B. Zhang W, et al. Front Bioeng Biotechnol. 2022 Sep 28;10:918866. doi: 10.3389/fbioe.2022.918866. eCollection 2022. Front Bioeng Biotechnol. 2022. PMID: 36246375 Free PMC article.
Our results revealed different modulation modes of the biomarker expression in osteoblasts, namely cell origin/bone entity-dependent, and culture configuration- and/or time-dependent modulations. SEMA3A, SPP1, BGLAP and PHEX demonstrated the strongest dependence on cell or …
Our results revealed different modulation modes of the biomarker expression in osteoblasts, namely cell origin/bone entity-dependent, and cu …
Development of microfluidic-based assays to estimate the binding between osteocalcin (BGLAP) and fluorescent antibodies.
Carmona H, Valadez H, Yun Y, Sankar J, Estala L, Gomez FA. Carmona H, et al. Talanta. 2015 Jan;132:676-9. doi: 10.1016/j.talanta.2014.10.025. Epub 2014 Oct 22. Talanta. 2015. PMID: 25476363
Osteocalcin (bone gamma-carboxyglutamate protein; BGLAP) is a highly conserved molecule associated with mineralization of bone matrix. ...Both techniques utilize sub-microliter volumes of material an important consideration when studying bone turnover markers (BTMs) like …
Osteocalcin (bone gamma-carboxyglutamate protein; BGLAP) is a highly conserved molecule associated with mineralization of bone matrix …
Possible Association Between Polymorphisms in ESR1, COL1A2, BGLAP, SPARC, VDR, and MMP2 Genes and Dental Fluorosis in a Population from an Endemic Region of West Bengal.
Chakraborty A, Pramanik S, Datta K, Goswami R, Saha D, Majumdar KK, Sikdar N. Chakraborty A, et al. Biol Trace Elem Res. 2022 Nov;200(11):4641-4653. doi: 10.1007/s12011-021-03072-8. Epub 2022 Jan 23. Biol Trace Elem Res. 2022. PMID: 35066749
The present study was aimed at evaluating the association between 15 single-nucleotide polymorphisms (SNPs) in the six candidate genes (namely, ESR1, COL1A2, BGLAP, SPARC, VDR, and MMP2) and DF among 132 individuals (case = 71 and control = 61) living in a fluoride endemic …
The present study was aimed at evaluating the association between 15 single-nucleotide polymorphisms (SNPs) in the six candidate genes (name …
637 results