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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2003 1
2005 1
2006 1
2007 1
2009 1
2010 4
2011 1
2012 2
2013 2
2014 4
2015 3
2016 4
2017 3
2018 4
2019 10
2020 14
2021 20
2022 18
2023 14
2024 8

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97 results

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Page 1
BCL2L13: physiological and pathological meanings.
Meng F, Sun N, Liu D, Jia J, Xiao J, Dai H. Meng F, et al. Cell Mol Life Sci. 2021 Mar;78(6):2419-2428. doi: 10.1007/s00018-020-03702-9. Epub 2020 Nov 17. Cell Mol Life Sci. 2021. PMID: 33201252 Review.
BCL2L13 is a BCL2-like protein. It has been discovered for two decades, now on the way to be a hotspot of research with its physiological and pathological meanings found in recent years. ...Similar to BNIP3, BCL2L13 cannot be indiscriminately categorized into pro- o …
BCL2L13 is a BCL2-like protein. It has been discovered for two decades, now on the way to be a hotspot of research with its physiolog …
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma.
Wang J, Chen A, Xue Z, Liu J, He Y, Liu G, Zhao Z, Li W, Zhang Q, Chen A, Wang J, Li X, Wang X, Huang B. Wang J, et al. Cell Death Dis. 2023 Sep 2;14(9):585. doi: 10.1038/s41419-023-06112-4. Cell Death Dis. 2023. PMID: 37660127 Free PMC article.
Mechanistically, BCL2L13 targeted DNM1L at the Ser616 site, leading to mitochondrial fission and high mitophagy flux. ...Therefore, the regulation and biological function of BCL2L13 render it a candidate molecular target for treating GBM....
Mechanistically, BCL2L13 targeted DNM1L at the Ser616 site, leading to mitochondrial fission and high mitophagy flux. ...Therefore, t …
BCL2L13 is a mammalian homolog of the yeast mitophagy receptor Atg32.
Otsu K, Murakawa T, Yamaguchi O. Otsu K, et al. Autophagy. 2015;11(10):1932-3. doi: 10.1080/15548627.2015.1084459. Autophagy. 2015. PMID: 26506896 Free PMC article. Review.
BCL2L13 is indispensable for mitochondrial damage-induced fragmentation and mitophagy. Furthermore, BCL2L13 induces mitophagy in Atg32-deficient yeast. Induction and/or phosphorylation of BCL2L13 may regulate its activity. ...
BCL2L13 is indispensable for mitochondrial damage-induced fragmentation and mitophagy. Furthermore, BCL2L13 induces mitophagy …
Therapeutic regulation of autophagy in hepatic metabolism.
Byrnes K, Blessinger S, Bailey NT, Scaife R, Liu G, Khambu B. Byrnes K, et al. Acta Pharm Sin B. 2022 Jan;12(1):33-49. doi: 10.1016/j.apsb.2021.07.021. Epub 2021 Jul 28. Acta Pharm Sin B. 2022. PMID: 35127371 Free PMC article. Review.
Mitophagy in tumorigenesis and metastasis.
Poole LP, Macleod KF. Poole LP, et al. Cell Mol Life Sci. 2021 Apr;78(8):3817-3851. doi: 10.1007/s00018-021-03774-1. Epub 2021 Feb 13. Cell Mol Life Sci. 2021. PMID: 33580835 Free PMC article. Review.
The multifaceted regulation of mitophagy by endogenous metabolites.
Zhang T, Liu Q, Gao W, Sehgal SA, Wu H. Zhang T, et al. Autophagy. 2022 Jun;18(6):1216-1239. doi: 10.1080/15548627.2021.1975914. Epub 2021 Sep 29. Autophagy. 2022. PMID: 34583624 Free PMC article.
We also highlight the key regulations of mammalian mitophagy by endogenous metabolites, shed new light on the bidirectional interplay between mitophagy and cellular metabolisms, with attempting to provide a perspective insight into the nutritional intervention of metabolic disord …
We also highlight the key regulations of mammalian mitophagy by endogenous metabolites, shed new light on the bidirectional interplay betwee …
The role of BCL2L13 in glioblastoma: turning a need into a target.
Jacobs J, Iranpour R, Behrooz AB, da Silva Rosa SC, Ghavami S. Jacobs J, et al. Biochem Cell Biol. 2024 Apr 1;102(2):127-134. doi: 10.1139/bcb-2023-0221. Epub 2023 Nov 21. Biochem Cell Biol. 2024. PMID: 37988705 Free article. Review.
A proposed mechanism for bypassing apoptosis is decreased ceramide levels, and previous research has shown that within GBM cells, B cell lymphoma 2-like 13 (BCL2L13) can inhibit ceramide synthase. This review aims to discuss the causes of resistance in GBM cells, followed …
A proposed mechanism for bypassing apoptosis is decreased ceramide levels, and previous research has shown that within GBM cells, B cell lym …
Emerging views of mitophagy in immunity and autoimmune diseases.
Xu Y, Shen J, Ran Z. Xu Y, et al. Autophagy. 2020 Jan;16(1):3-17. doi: 10.1080/15548627.2019.1603547. Epub 2019 Apr 21. Autophagy. 2020. PMID: 30951392 Free PMC article.
In addition, we further discuss the direct and indirect evidence linking mitophagy to inflammation and autoimmunity underlying the pathogenesis of autoimmune diseases including inflammatory bowel diseases (IBD), systemic lupus erythematosus (SLE) and primary biliary cirrhosis (PB …
In addition, we further discuss the direct and indirect evidence linking mitophagy to inflammation and autoimmunity underlying the pathogene …
Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles.
Yao RQ, Ren C, Xia ZF, Yao YM. Yao RQ, et al. Autophagy. 2021 Feb;17(2):385-401. doi: 10.1080/15548627.2020.1725377. Epub 2020 Feb 12. Autophagy. 2021. PMID: 32048886 Free PMC article. Review.
In this review, we summarized the recent findings and mechanisms covering different kinds of organelle-specific autophagy, as well as their involvement in various diseases, aiming to arouse concern about the significance of the quality control of multiple organelles in the treatm …
In this review, we summarized the recent findings and mechanisms covering different kinds of organelle-specific autophagy, as well as their …
Bcl2L13 is a ceramide synthase inhibitor in glioblastoma.
Jensen SA, Calvert AE, Volpert G, Kouri FM, Hurley LA, Luciano JP, Wu Y, Chalastanis A, Futerman AH, Stegh AH. Jensen SA, et al. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5682-7. doi: 10.1073/pnas.1316700111. Epub 2014 Mar 31. Proc Natl Acad Sci U S A. 2014. PMID: 24706805 Free PMC article.
Therapy resistance is a major limitation to the successful treatment of cancer. Here, we identify Bcl2-like 13 (Bcl2L13), an atypical member of the Bcl-2 family, as a therapy susceptibility gene with elevated expression in solid and blood cancers, including glioblastoma (G …
Therapy resistance is a major limitation to the successful treatment of cancer. Here, we identify Bcl2-like 13 (Bcl2L13), an atypical …
97 results