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Year Number of Results
1985 1
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1992 2
1993 2
1994 2
1996 1
1997 3
1998 1
1999 3
2000 2
2001 2
2002 4
2003 6
2004 4
2005 7
2006 12
2007 6
2008 9
2009 7
2010 11
2011 13
2012 11
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2024 17

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360 results

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Page 1
APOA4 as a novel predictor of prognosis in Stevens-Johnson syndrome/toxic epidermal necrolysis: A proteomics analysis from two prospective cohorts.
Gong T, Zhang P, Ruan SF, Xiao Z, Chen W, Lin M, Zhong Q, Luo R, Xu Q, Peng J, Cheng B, Chen F, Chen L, Chung WH, Ji C. Gong T, et al. J Am Acad Dermatol. 2023 Jul;89(1):45-52. doi: 10.1016/j.jaad.2023.02.058. Epub 2023 Mar 22. J Am Acad Dermatol. 2023. PMID: 36963506
Thus further research will be helpful to effectively incorporate APOA4 into current SCORTEN-driven protocols. LIMITATIONS: The cohort size is relatively small. ...CONCLUSION: Adalimumab in combination with corticosteroids demonstrates significant clinical benefits over cor …
Thus further research will be helpful to effectively incorporate APOA4 into current SCORTEN-driven protocols. LIMITATIONS: The cohort …
Serum APOA4 Pharmacodynamically Represents Administered Recombinant Human Hepatocyte Growth Factor (E3112).
Motoi S, Uesugi M, Obara T, Moriya K, Arita Y, Ogasawara H, Soejima M, Imai T, Kawano T. Motoi S, et al. Int J Mol Sci. 2021 Apr 27;22(9):4578. doi: 10.3390/ijms22094578. Int J Mol Sci. 2021. PMID: 33925510 Free PMC article.
Serum APOA4 levels were increased after rh-HGF administration, not only in normal mice but also in anti-Fas-induced murine acute liver failure (ALF), which confirmed the pharmacodynamic nature of APOA4. CONCLUSIONS: APOA4 was identified as a soluble PD marker …
Serum APOA4 levels were increased after rh-HGF administration, not only in normal mice but also in anti-Fas-induced murine acute live …
Single-cell RNA sequencing reveals a novel inhibitory effect of ApoA4 on NAFL mediated by liver-specific subsets of myeloid cells.
Liu XH, Zhou JT, Yan CX, Cheng C, Fan JN, Xu J, Zheng Q, Bai Q, Li Z, Li S, Li X. Liu XH, et al. Front Immunol. 2022 Nov 8;13:1038401. doi: 10.3389/fimmu.2022.1038401. eCollection 2022. Front Immunol. 2022. PMID: 36426356 Free PMC article.
The aim of this study was to profile the hepatic immune cells affected by ApoA4 in NAFL. We performed scRNA-seq on liver immune cells from WT and ApoA4-deficient mice administered a high-fat diet. ...The expression of NE and IL-1beta in granulocytes and macrophages …
The aim of this study was to profile the hepatic immune cells affected by ApoA4 in NAFL. We performed scRNA-seq on liver immune cells …
Autosomal dominant ApoA4 mutations present as tubulointerstitial kidney disease with medullary amyloidosis.
Kmochová T, Kidd KO, Orr A, Hnízda A, Hartmannová H, Hodaňová K, Vyleťal P, Naušová K, Brinsa V, Trešlová H, Sovová J, Barešová V, Svojšová K, Vrbacká A, Stránecký V, Robins VC, Taylor A, Martin L, Rivas-Chavez A, Payne R, Bleyer HA, Williams A, Rennke HG, Weins A, Short PJ, Agrawal V, Storsley LJ, Waikar SS, McPhail ED, Dasari S, Leung N, Hewlett T, Yorke J, Gaston D, Geldenhuys L, Samuels M, Levine AP, West M, Hůlková H, Pompach P, Novák P, Weinberg RB, Bedard K, Živná M, Sikora J, Bleyer AJ Sr, Kmoch S. Kmochová T, et al. Kidney Int. 2024 Apr;105(4):799-811. doi: 10.1016/j.kint.2023.11.021. Epub 2023 Dec 12. Kidney Int. 2024. PMID: 38096951
Fifteen genetically affected individuals presented with higher plasma ApoA4 concentrations. Kidney pathologic specimens from four individuals revealed amyloid deposits limited to the medulla, with the mutated ApoA4 identified by mass-spectrometry as the predominant …
Fifteen genetically affected individuals presented with higher plasma ApoA4 concentrations. Kidney pathologic specimens from four ind …
Serum ApoA4 levels predicted the progression of renal impairment in T2DM.
Cheng CW, Chang CC, Chen HW, Lin CY, Chen JS. Cheng CW, et al. Eur J Clin Invest. 2018 Jun;48(6):e12937. doi: 10.1111/eci.12937. Epub 2018 May 13. Eur J Clin Invest. 2018. PMID: 29675916
In addition, significant positive correlations were observed between ApoA4 and blood urea nitrogen levels and between ApoA4 and creatine levels, while significant negative correlations were seen between serum protein levels and between serum albumin levels in compar …
In addition, significant positive correlations were observed between ApoA4 and blood urea nitrogen levels and between ApoA4 an …
Effect of ApoA4 on SERPINA3 mediated by nuclear receptors NR4A1 and NR1D1 in hepatocytes.
Zhang Y, He J, Zhao J, Xu M, Lou D, Tso P, Li Z, Li X. Zhang Y, et al. Biochem Biophys Res Commun. 2017 May 27;487(2):327-332. doi: 10.1016/j.bbrc.2017.04.058. Epub 2017 Apr 13. Biochem Biophys Res Commun. 2017. PMID: 28412351 Free PMC article.
ApoA4 exerts anti-inflammatory effects, but the mechanism remains unclear. ...These data suggests that ApoA4 transcriptionally induced SERPINA3 expression via NR1D1 and NR4A1. ...
ApoA4 exerts anti-inflammatory effects, but the mechanism remains unclear. ...These data suggests that ApoA4 transcriptionally …
A long non-coding RNA, APOA4-AS, regulates APOA4 expression depending on HuR in mice.
Qin W, Li X, Xie L, Li S, Liu J, Jia L, Dong X, Ren X, Xiao J, Yang C, Zhou Y, Chen Z. Qin W, et al. Nucleic Acids Res. 2016 Jul 27;44(13):6423-33. doi: 10.1093/nar/gkw341. Epub 2016 Apr 29. Nucleic Acids Res. 2016. PMID: 27131369 Free PMC article.
APOA4-AS has a similar expression pattern with APOA4 gene. The expressions of APOA4-AS and APOA4 are both abnormally elevated in the liver of ob/ob mice and patients with fatty liver disease. ...Deletion of HuR dramatically reduces both APOA4-AS …
APOA4-AS has a similar expression pattern with APOA4 gene. The expressions of APOA4-AS and APOA4 are both abnorm …
HDL anti-inflammatory function is impaired and associated with high SAA1 and low APOA4 levels in aneurysmal subarachnoid hemorrhage.
Azúa-López ZR, Pezzotti MR, González-Díaz Á, Meilhac O, Ureña J, Amaya-Villar R, Castellano A, Varela LM. Azúa-López ZR, et al. J Cereb Blood Flow Metab. 2023 Nov;43(11):1919-1930. doi: 10.1177/0271678X231184806. Epub 2023 Jun 26. J Cereb Blood Flow Metab. 2023. PMID: 37357772 Free PMC article.
We confirmed by western blot that low levels of apolipoprotein A4 (APOA4) and high of serum amyloid A1 (SAA1) in HDL were associated with the lack of anti-inflammatory function observed in aSAH. ...
We confirmed by western blot that low levels of apolipoprotein A4 (APOA4) and high of serum amyloid A1 (SAA1) in HDL were associated …
Low-density lipoprotein receptor-related protein 1 (LRP1) is a novel receptor for apolipoprotein A4 (APOA4) in adipose tissue.
Qu J, Fourman S, Fitzgerald M, Liu M, Nair S, Oses-Prieto J, Burlingame A, Morris JH, Davidson WS, Tso P, Bhargava A. Qu J, et al. Sci Rep. 2021 Jun 24;11(1):13289. doi: 10.1038/s41598-021-92711-0. Sci Rep. 2021. PMID: 34168225 Free PMC article.
Since its discovery nearly 4 decades ago, to date, only platelet integrin alphaIIbbeta3 has been identified as APOA4 receptor in the plasma. Using co-immunoprecipitation coupled with mass spectrometry, we probed the APOA4 interactome in mouse gonadal fat tissue, whe …
Since its discovery nearly 4 decades ago, to date, only platelet integrin alphaIIbbeta3 has been identified as APOA4 receptor in the …
The Variants at APOA1 and APOA4 Contribute to the Susceptibility of Schizophrenia With Inhibiting mRNA Expression in Peripheral Blood Leukocytes.
Fan Y, Gao J, Li Y, Chen X, Zhang T, You W, Xue Y, Shen C. Fan Y, et al. Front Mol Biosci. 2021 Dec 6;8:785445. doi: 10.3389/fmolb.2021.785445. eCollection 2021. Front Mol Biosci. 2021. PMID: 34938775 Free PMC article.
This study mainly aimed to evaluate the association of variants at apolipoprotein A1 (APOA1) and APOA4 with SZ in a Chinese Han population. Methods: The rs5072 of APOA1 and rs1268354 of APOA4 were examined in a case-control study involving 2,680 patients with SZ fro …
This study mainly aimed to evaluate the association of variants at apolipoprotein A1 (APOA1) and APOA4 with SZ in a Chinese Han popul …
360 results