Similar articles for PMID: 16014412

Year	Number of Results
1988	1
1992	1
1993	1
1995	2
1997	2
1998	1
1999	1
2002	1
2003	2
2004	4
2005	14
2006	13
2007	12
2008	22
2009	16
2010	20
2011	23
2012	21
2013	23
2014	21
2015	21
2016	31
2017	24
2018	27
2019	27
2020	29
2021	28
2022	29
2023	14
2024	0

1

Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation.

Yang SH, Bergo MO, Toth JI, Qiao X, Hu Y, Sandoval S, Meta M, Bendale P, Gelb MH, Young SG, Fong LG. Yang SH, et al. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10291-6. doi: 10.1073/pnas.0504641102. Epub 2005 Jul 12. Proc Natl Acad Sci U S A. 2005. PMID: 16014412 Free PMC article.

2

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome.

Capell BC, Erdos MR, Madigan JP, Fiordalisi JJ, Varga R, Conneely KN, Gordon LB, Der CJ, Cox AD, Collins FS. Capell BC, et al. Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12879-84. doi: 10.1073/pnas.0506001102. Epub 2005 Aug 29. Proc Natl Acad Sci U S A. 2005. PMID: 16129833 Free PMC article.

3

Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes.

Toth JI, Yang SH, Qiao X, Beigneux AP, Gelb MH, Moulson CL, Miner JH, Young SG, Fong LG. Toth JI, et al. Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12873-8. doi: 10.1073/pnas.0505767102. Epub 2005 Aug 29. Proc Natl Acad Sci U S A. 2005. PMID: 16129834 Free PMC article.

4

Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition.

Glynn MW, Glover TW. Glynn MW, et al. Hum Mol Genet. 2005 Oct 15;14(20):2959-69. doi: 10.1093/hmg/ddi326. Epub 2005 Aug 26. Hum Mol Genet. 2005. PMID: 16126733

5

Blocking protein farnesylation improves nuclear shape abnormalities in keratinocytes of mice expressing the prelamin A variant in Hutchinson-Gilford progeria syndrome.

Wang Y, Ostlund C, Worman HJ. Wang Y, et al. Nucleus. 2010 Sep-Oct;1(5):432-9. doi: 10.4161/nucl.1.5.12972. Nucleus. 2010. PMID: 21326826 Free PMC article.

6

Blocking farnesylation of the prelamin A variant in Hutchinson-Gilford progeria syndrome alters the distribution of A-type lamins.

Wang Y, Ostlund C, Choi JC, Swayne TC, Gundersen GG, Worman HJ. Wang Y, et al. Nucleus. 2012 Sep-Oct;3(5):452-62. doi: 10.4161/nucl.21675. Epub 2012 Aug 16. Nucleus. 2012. PMID: 22895092 Free PMC article.

7

Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome.

Mallampalli MP, Huyer G, Bendale P, Gelb MH, Michaelis S. Mallampalli MP, et al. Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14416-21. doi: 10.1073/pnas.0503712102. Epub 2005 Sep 26. Proc Natl Acad Sci U S A. 2005. PMID: 16186497 Free PMC article.

8

N6-isopentenyladenosine improves nuclear shape in fibroblasts from humans with progeroid syndromes by inhibiting the farnesylation of prelamin A.

Bifulco M, D'Alessandro A, Paladino S, Malfitano AM, Notarnicola M, Caruso MG, Laezza C. Bifulco M, et al. FEBS J. 2013 Dec;280(23):6223-32. doi: 10.1111/febs.12544. Epub 2013 Nov 18. FEBS J. 2013. PMID: 24112551 Free article.

9

Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture.

Rivera-Torres J, Acín-Perez R, Cabezas-Sánchez P, Osorio FG, Gonzalez-Gómez C, Megias D, Cámara C, López-Otín C, Enríquez JA, Luque-García JL, Andrés V. Rivera-Torres J, et al. J Proteomics. 2013 Oct 8;91:466-77. doi: 10.1016/j.jprot.2013.08.008. Epub 2013 Aug 20. J Proteomics. 2013. PMID: 23969228

10

Prelamin A farnesylation and progeroid syndromes.

Young SG, Meta M, Yang SH, Fong LG. Young SG, et al. J Biol Chem. 2006 Dec 29;281(52):39741-5. doi: 10.1074/jbc.R600033200. Epub 2006 Nov 7. J Biol Chem. 2006. PMID: 17090536 Free article. Review.

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