A between-experiment analysis of relationships linking dietary protein intake and post-weaning diarrhea in weanling pigs under conditions of experimental infection with an enterotoxigenic strain of Escherichia coli

Anim Sci J. 2015 Mar;86(3):286-93. doi: 10.1111/asj.12275. Epub 2014 Sep 18.

Abstract

Numerous experiments have demonstrated that feeding a lower protein diet decreases protein fermentation in the gastrointestinal tract (GIT) and reduces the incidence of post-weaning diarrhea (PWD). However, there is a lack of holistic evidence underpinning the relationship between feeding a lower protein diet and PWD in relation to physiological responses and protein fermentation in the GIT. The scope of this article, therefore, will: (i) focus on the impact of dietary protein levels on selected indices of GIT health in weaned pigs without and with experimental infection with an enterotoxigenic strain of Escherichia coli; and (ii) attempt to conduct regression analysis to examine the relationships between dietary-origin protein intake, nitrogen fermentation indices, fecal consistency and the incidence of PWD. We used datasets generated from a series of four intensive experiments in weaned pigs. The collective results derived from these datasets indicate that restriction of daily protein intake to less than 60 g through feeding a lower protein diet for as little as 7 days after weaning reduced the incidence of PWD commensurate with a reduction in protein fermentation indices.

Keywords: antimicrobial compounds; diet; pig; post-weaning diarrhea; protein.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animal Feed*
  • Animals
  • Datasets as Topic
  • Diarrhea / etiology*
  • Diarrhea / prevention & control*
  • Diet, Protein-Restricted*
  • Dietary Proteins / administration & dosage*
  • Dietary Proteins / metabolism
  • Escherichia coli Infections / complications*
  • Fermentation
  • Gastrointestinal Tract / metabolism*
  • Nitrogen / metabolism
  • Regression Analysis
  • Swine
  • Weaning

Substances

  • Dietary Proteins
  • Nitrogen