PubMed

Telomeric D-loops containing 8-oxo-2'-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1.

Ghosh A, Rossi ML, Aulds J, Croteau D, Bohr VA.

J Biol Chem. 2009 Nov 6;284(45):31074-84. Epub 2009 Sep 4.PMID: 19734539 [PubMed - in process]Related articles

Werner syndrome resembles normal aging.

Kyng K, Croteau DL, Bohr VA.

Cell Cycle. 2009 Aug;8(15):2323. Epub 2009 Aug 1. No abstract available. PMID: 19633413 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct and indirect roles of RECQL4 in modulating base excision repair capacity.

Schurman SH, Hedayati M, Wang Z, Singh DK, Speina E, Zhang Y, Becker K, Macris M, Sung P, Wilson DM 3rd, Croteau DL, Bohr VA.

Hum Mol Genet. 2009 Sep 15;18(18):3470-83. Epub 2009 Jun 29.PMID: 19567405 [PubMed - in process]Related articles

Role of mitochondrial hOGG1 and aconitase in oxidant-induced lung epithelial cell apoptosis.

Panduri V, Liu G, Surapureddi S, Kondapalli J, Soberanes S, de Souza-Pinto NC, Bohr VA, Budinger GR, Schumacker PT, Weitzman SA, Kamp DW.

Free Radic Biol Med. 2009 Sep 15;47(6):750-9. Epub 2009 Jun 12.PMID: 19524665 [PubMed - in process]Related articles

The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells.

de Souza-Pinto NC, Maynard S, Hashiguchi K, Hu J, Muftuoglu M, Bohr VA.

Mol Cell Biol. 2009 Aug;29(16):4441-54. Epub 2009 Jun 8.PMID: 19506022 [PubMed - indexed for MEDLINE]Related articles

A potential impact of DNA repair on ageing and lifespan in the ageing model organism Podospora anserina: decrease in mitochondrial DNA repair activity during ageing.

Soerensen M, Gredilla R, Müller-Ohldach M, Werner A, Bohr VA, Osiewacz HD, Stevnsner T.

Mech Ageing Dev. 2009 Aug;130(8):487-96. Epub 2009 May 30.PMID: 19486911 [PubMed - indexed for MEDLINE]Related articles

Cockayne syndrome group B protein is engaged in processing of DNA adducts of lipid peroxidation product trans-4-hydroxy-2-nonenal.

Maddukuri L, Speina E, Christiansen M, Dudzińska D, Zaim J, Obtułowicz T, Kabaczyk S, Komisarski M, Bukowy Z, Szczegielniak J, Wójcik A, Kuśmierek JT, Stevnsner T, Bohr VA, Tudek B.

Mutat Res. 2009 Jun 18;666(1-2):23-31. Epub 2009 Mar 31.PMID: 19481676 [PubMed - indexed for MEDLINE]Related articles

[Is the concept "otogenic meningitis" a misunderstanding?]

Rasmussen N, Hjuler T, Bohr VA, Cayé-Thomasen P.

Ugeskr Laeger. 2009 Apr 27;171(18):1480. Danish. No abstract available. PMID: 19419624 [PubMed - indexed for MEDLINE]Related articles

Novel DNA mismatch-repair activity involving YB-1 in human mitochondria.

de Souza-Pinto NC, Mason PA, Hashiguchi K, Weissman L, Tian J, Guay D, Lebel M, Stevnsner TV, Rasmussen LJ, Bohr VA.

DNA Repair (Amst). 2009 Jun 4;8(6):704-19. Epub 2009 Mar 9.PMID: 19272840 [PubMed - indexed for MEDLINE]Related articles

Mechanism of Werner DNA helicase: POT1 and RPA stimulates WRN to unwind beyond gaps in the translocating strand.

Ahn B, Lee JW, Jung H, Beck G, Bohr VA.

PLoS One. 2009;4(3):e4673. Epub 2009 Mar 5.PMID: 19262689 [PubMed - indexed for MEDLINE]Related articlesFree article

Bloom's syndrome workshop focuses on the functional specificities of RecQ helicases.

Ellis NA, Sander M, Harris CC, Bohr VA.

Mech Ageing Dev. 2008 Nov;129(11):681-91.PMID: 19238688 [PubMed - indexed for MEDLINE]Related articles

Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase.

Muftuoglu M, de Souza-Pinto NC, Dogan A, Aamann M, Stevnsner T, Rybanska I, Kirkali G, Dizdaroglu M, Bohr VA.

J Biol Chem. 2009 Apr 3;284(14):9270-9. Epub 2009 Jan 29.PMID: 19179336 [PubMed - indexed for MEDLINE]Related articles

Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging.

Singh DK, Ahn B, Bohr VA.

Biogerontology. 2009 Jun;10(3):235-52. Epub 2008 Dec 15. Review.PMID: 19083132 [PubMed - indexed for MEDLINE]Related articles

Accumulation of (5'S)-8,5'-cyclo-2'-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice.

Kirkali G, de Souza-Pinto NC, Jaruga P, Bohr VA, Dizdaroglu M.

DNA Repair (Amst). 2009 Feb 1;8(2):274-8. Epub 2008 Nov 18.PMID: 18992371 [PubMed - indexed for MEDLINE]Related articlesFree article

Base excision repair of oxidative DNA damage and association with cancer and aging.

Maynard S, Schurman SH, Harboe C, de Souza-Pinto NC, Bohr VA.

Carcinogenesis. 2009 Jan;30(1):2-10. Epub 2008 Oct 31. Review.PMID: 18978338 [PubMed - indexed for MEDLINE]Related articles

Opinion section on frailty.

Fried LP, Varadhan R, Bohr VA.

Mech Ageing Dev. 2008 Nov;129(11):665. Epub 2008 Oct 4. No abstract available. PMID: 18951913 [PubMed - indexed for MEDLINE]Related articles

Von Hippel-Lindau-coupled and transcription-coupled nucleotide excision repair-dependent degradation of RNA polymerase II in response to trabectedin.

Aune GJ, Takagi K, Sordet O, Guirouilh-Barbat J, Antony S, Bohr VA, Pommier Y.

Clin Cancer Res. 2008 Oct 15;14(20):6449-55.PMID: 18927284 [PubMed - indexed for MEDLINE]Related articlesFree article

Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance.

Bohr VA.

Trends Biochem Sci. 2008 Dec;33(12):609-20. Epub 2008 Oct 14. Review.PMID: 18926708 [PubMed - indexed for MEDLINE]Related articlesFree article

The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis.

Muftuoglu M, Oshima J, von Kobbe C, Cheng WH, Leistritz DF, Bohr VA.

Hum Genet. 2008 Nov;124(4):369-77. Epub 2008 Sep 23. Review.PMID: 18810497 [PubMed - indexed for MEDLINE]Related articles

WRN protects against topo I but not topo II inhibitors by preventing DNA break formation.

Christmann M, Tomicic MT, Gestrich C, Roos WP, Bohr VA, Kaina B.

DNA Repair (Amst). 2008 Dec 1;7(12):1999-2009. Epub 2008 Oct 15.PMID: 18805512 [PubMed - indexed for MEDLINE]Related articlesFree article