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    Results: 1 to 20 of 61

    1.

    Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity.

    Wang XJ, Sun Z, Chen W, Eblin KE, Gandolfi JA, Zhang DD.

    Toxicol Appl Pharmacol. 2007 Dec 1;225(2):206-13. Epub 2007 Aug 7.PMID: 17765279 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Keap1 eye on the target: chemoprevention of liver cancer.

    Yates MS, Kensler TW.

    Acta Pharmacol Sin. 2007 Sep;28(9):1331-42. Review.PMID: 17723167 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Effects of oridonin on proliferation of HT29 human colon carcinoma cell lines both in vitro and in vivo in mice.

    Zhu Y, Xie L, Chen G, Wang H, Zhang R.

    Pharmazie. 2007 Jun;62(6):439-44.PMID: 17663191 [PubMed - indexed for MEDLINE]Related articles

    4.

    Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.

    Sun Z, Zhang S, Chan JY, Zhang DD.

    Mol Cell Biol. 2007 Sep;27(18):6334-49. Epub 2007 Jul 16.PMID: 17636022 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element.

    Nishinaka T, Ichijo Y, Ito M, Kimura M, Katsuyama M, Iwata K, Miura T, Terada T, Yabe-Nishimura C.

    Toxicol Lett. 2007 May 15;170(3):238-47. Epub 2007 Mar 24.PMID: 17449203 [PubMed - indexed for MEDLINE]Related articles

    6.

    Back to the future of oridonin: again, compound from medicinal herb shows potent antileukemia efficacies in vitro and in vivo.

    Zhou GB, Chen SJ, Wang ZY, Chen Z.

    Cell Res. 2007 Apr;17(4):274-6. No abstract available. PMID: 17426700 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Oridonin inhibited the tyrosine kinase activity and induced apoptosis in human epidermoid carcinoma A431 cells.

    Li D, Wu LJ, Tashiro S, Onodera S, Ikejima T.

    Biol Pharm Bull. 2007 Feb;30(2):254-60.PMID: 17268061 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo.

    Zhou GB, Kang H, Wang L, Gao L, Liu P, Xie J, Zhang FX, Weng XQ, Shen ZX, Chen J, Gu LJ, Yan M, Zhang DE, Chen SJ, Wang ZY, Chen Z.

    Blood. 2007 Apr 15;109(8):3441-50. Epub 2006 Dec 29.PMID: 17197433 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Mechanistic studies of the Nrf2-Keap1 signaling pathway.

    Zhang DD.

    Drug Metab Rev. 2006;38(4):769-89. Review.PMID: 17145701 [PubMed - indexed for MEDLINE]Related articles

    11.

    Induction of antioxidant and detoxification response by oxidants in cardiomyocytes: evidence from gene expression profiling and activation of Nrf2 transcription factor.

    Purdom-Dickinson SE, Lin Y, Dedek M, Morrissy S, Johnson J, Chen QM.

    J Mol Cell Cardiol. 2007 Jan;42(1):159-76. Epub 2006 Nov 1.PMID: 17081560 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Arsenic: signal transduction, transcription factor, and biotransformation involved in cellular response and toxicity.

    Kumagai Y, Sumi D.

    Annu Rev Pharmacol Toxicol. 2007;47:243-62. Review.PMID: 17002598 [PubMed - indexed for MEDLINE]Related articles

    13.

    Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species.

    Kobayashi M, Yamamoto M.

    Adv Enzyme Regul. 2006;46:113-40. Epub 2006 Aug 2. Review. No abstract available. PMID: 16887173 [PubMed - indexed for MEDLINE]Related articles

    14.

    Increased mortality from lung cancer and bronchiectasis in young adults after exposure to arsenic in utero and in early childhood.

    Smith AH, Marshall G, Yuan Y, Ferreccio C, Liaw J, von Ehrenstein O, Steinmaus C, Bates MN, Selvin S.

    Environ Health Perspect. 2006 Aug;114(8):1293-6.PMID: 16882542 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.

    He X, Chen MG, Lin GX, Ma Q.

    J Biol Chem. 2006 Aug 18;281(33):23620-31. Epub 2006 Jun 19.PMID: 16785233 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Sulforaphane, an activator of Nrf2, suppresses cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes.

    Shinkai Y, Sumi D, Fukami I, Ishii T, Kumagai Y.

    FEBS Lett. 2006 Mar 20;580(7):1771-4. Epub 2006 Feb 24.PMID: 16516206 [PubMed - indexed for MEDLINE]Related articles

    17.

    Nrf2: a potential molecular target for cancer chemoprevention by natural compounds.

    Jeong WS, Jun M, Kong AN.

    Antioxid Redox Signal. 2006 Jan-Feb;8(1-2):99-106. Review.PMID: 16487042 [PubMed - indexed for MEDLINE]Related articles

    18.

    Induction of endogenous Nrf2/small maf heterodimers by arsenic-mediated stress in placental choriocarcinoma cells.

    Massrieh W, Derjuga A, Blank V.

    Antioxid Redox Signal. 2006 Jan-Feb;8(1-2):53-9.PMID: 16487037 [PubMed - indexed for MEDLINE]Related articles

    19.

    Antiproliferation effects of oridonin on HPB-ALL cells and its mechanisms of action.

    Liu JJ, Huang RW, Lin DJ, Wu XY, Peng J, Pan XL, Lin Q, Hou M, Zhang MH, Chen F.

    Am J Hematol. 2006 Feb;81(2):86-94.PMID: 16432862 [PubMed - indexed for MEDLINE]Related articles

    20.

    Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice.

    Hu X, Roberts JR, Apopa PL, Kan YW, Ma Q.

    Mol Cell Biol. 2006 Feb;26(3):940-54.PMID: 16428448 [PubMed - indexed for MEDLINE]Related articlesFree article

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