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The OECD program to validate the rat Hershberger bioassay to screen compounds for in vivo androgen and antiandrogen responses. Phase 1: use of a potent agonist and a potent antagonist to test the standardized protocol.

Owens W, Zeiger E, Walker M, Ashby J, Onyon L, Gray LE Jr.

Environ Health Perspect. 2006 Aug;114(8):1259-65.PMID: 16882536 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of in utero exposure to finasteride on androgen-dependent reproductive development in the male rat.

Bowman CJ, Barlow NJ, Turner KJ, Wallace DG, Foster PM.

Toxicol Sci. 2003 Aug;74(2):393-406. Epub 2003 May 28.PMID: 12773767 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro and in vivo effects of 17beta-trenbolone: a feedlot effluent contaminant.

Wilson VS, Lambright C, Ostby J, Gray LE Jr.

Toxicol Sci. 2002 Dec;70(2):202-11.PMID: 12441365 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of in utero linuron exposure on rat Wolffian duct development.

McIntyre BS, Barlow NJ, Sar M, Wallace DG, Foster PM.

Reprod Toxicol. 2002 Mar-Apr;16(2):131-9.PMID: 11955944 [PubMed - indexed for MEDLINE]Related articles

Male rats exposed to linuron in utero exhibit permanent changes in anogenital distance, nipple retention, and epididymal malformations that result in subsequent testicular atrophy.

McIntyre BS, Barlow NJ, Foster PM.

Toxicol Sci. 2002 Jan;65(1):62-70.PMID: 11752686 [PubMed - indexed for MEDLINE]Related articlesFree article

Pre- and postnatal oral toxicity of vinclozolin in Wistar and Long-Evans rats.

Hellwig J, van Ravenzwaay B, Mayer M, Gembardt C.

Regul Toxicol Pharmacol. 2000 Aug;32(1):42-50.PMID: 11029267 [PubMed - indexed for MEDLINE]Related articles

Effects of in utero exposure to linuron on androgen-dependent reproductive development in the male Crl:CD(SD)BR rat.

McIntyre BS, Barlow NJ, Wallace DG, Maness SC, Gaido KW, Foster PM.

Toxicol Appl Pharmacol. 2000 Sep 1;167(2):87-99.PMID: 10964759 [PubMed - indexed for MEDLINE]Related articles

Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat.

Gray LE Jr, Wolf C, Lambright C, Mann P, Price M, Cooper RL, Ostby J.

Toxicol Ind Health. 1999 Jan-Mar;15(1-2):94-118.PMID: 10188194 [PubMed - indexed for MEDLINE]Related articles

The fungicide procymidone alters sexual differentiation in the male rat by acting as an androgen-receptor antagonist in vivo and in vitro.

Ostby J, Kelce WR, Lambright C, Wolf CJ, Mann P, Gray LE Jr.

Toxicol Ind Health. 1999 Jan-Mar;15(1-2):80-93.PMID: 10188193 [PubMed - indexed for MEDLINE]Related articles

Peripubertal exposure to the antiandrogenic fungicide, vinclozolin, delays puberty, inhibits the development of androgen-dependent tissues, and alters androgen receptor function in the male rat.

Monosson E, Kelce WR, Lambright C, Ostby J, Gray LE Jr.

Toxicol Ind Health. 1999 Jan-Mar;15(1-2):65-79.PMID: 10188192 [PubMed - indexed for MEDLINE]Related articles

Impaired male sexual development in perinatal Sprague-Dawley and Long-Evans hooded rats exposed in utero and lactationally to p,p'-DDE.

You L, Casanova M, Archibeque-Engle S, Sar M, Fan LQ, Heck HA.

Toxicol Sci. 1998 Oct;45(2):162-73.PMID: 9848123 [PubMed - indexed for MEDLINE]Related articles

Developmental effects of an environmental antiandrogen: the fungicide vinclozolin alters sex differentiation of the male rat.

Gray LE Jr, Ostby JS, Kelce WR.

Toxicol Appl Pharmacol. 1994 Nov;129(1):46-52.PMID: 7974495 [PubMed - indexed for MEDLINE]Related articles

Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist.

Kelce WR, Stone CR, Laws SC, Gray LE, Kemppainen JA, Wilson EM.

Nature. 1995 Jun 15;375(6532):581-5.PMID: 7791873 [PubMed - indexed for MEDLINE]Related articles

Nipple differentiation in fetal male rats treated with an inhibitor of the enzyme 5 alpha-reductase: definition of a selective role for dihydrotestosterone.

Imperato-McGinley J, Binienda Z, Gedney J, Vaughan ED Jr.

Endocrinology. 1986 Jan;118(1):132-7.PMID: 3940851 [PubMed - indexed for MEDLINE]Related articles

External genitalia abnormalities in male rats exposed in utero to finasteride, a 5 alpha-reductase inhibitor.

Clark RL, Antonello JM, Grossman SJ, Wise LD, Anderson C, Bagdon WJ, Prahalada S, MacDonald JS, Robertson RT.

Teratology. 1990 Jul;42(1):91-100.PMID: 2168096 [PubMed - indexed for MEDLINE]Related articles

Comparison of the effects of the 5 alpha-reductase inhibitor finasteride and the antiandrogen flutamide on prostate and genital differentiation: dose-response studies.

Imperato-McGinley J, Sanchez RS, Spencer JR, Yee B, Vaughan ED.

Endocrinology. 1992 Sep;131(3):1149-56.PMID: 1324152 [PubMed - indexed for MEDLINE]Related articles