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    Results: 1 to 20 of 45

    1.

    Polychlorinated biphenyls suppress thyroid hormone-induced transactivation.

    Iwasaki T, Miyazaki W, Takeshita A, Kuroda Y, Koibuchi N.

    Biochem Biophys Res Commun. 2002 Dec 6;299(3):384-8.PMID: 12445811 [PubMed - indexed for MEDLINE]Related articles

    2.

    The nuclear receptor PXR: a master regulator of "homeland" defense.

    Dussault I, Forman BM.

    Crit Rev Eukaryot Gene Expr. 2002;12(1):53-64. Review.PMID: 12433065 [PubMed - indexed for MEDLINE]Related articles

    3.

    Metabolites of polychlorinated biphenyls in human liver and adipose tissue.

    Guvenius DM, Hassanzadeh P, Bergman A, Norén K.

    Environ Toxicol Chem. 2002 Nov;21(11):2264-9.PMID: 12389902 [PubMed - indexed for MEDLINE]Related articles

    4.

    Benzoate X receptors alpha and beta are pharmacologically distinct and do not function as xenobiotic receptors.

    Grün F, Venkatesan RN, Tabb MM, Zhou C, Cao J, Hemmati D, Blumberg B.

    J Biol Chem. 2002 Nov 15;277(46):43691-7. Epub 2002 Aug 26.PMID: 12198127 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.

    Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA.

    Mol Pharmacol. 2002 Sep;62(3):638-46.PMID: 12181440 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Sexual maturation in relation to polychlorinated aromatic hydrocarbons: Sharpe and Skakkebaek's hypothesis revisited.

    Den Hond E, Roels HA, Hoppenbrouwers K, Nawrot T, Thijs L, Vandermeulen C, Winneke G, Vanderschueren D, Staessen JA.

    Environ Health Perspect. 2002 Aug;110(8):771-6.PMID: 12153757 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    PXR, CAR and drug metabolism.

    Willson TM, Kliewer SA.

    Nat Rev Drug Discov. 2002 Apr;1(4):259-66. Review.PMID: 12120277 [PubMed - indexed for MEDLINE]Related articles

    8.

    Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice.

    Shimada T, Inoue K, Suzuki Y, Kawai T, Azuma E, Nakajima T, Shindo M, Kurose K, Sugie A, Yamagishi Y, Fujii-Kuriyama Y, Hashimoto M.

    Carcinogenesis. 2002 Jul;23(7):1199-207.PMID: 12117779 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Polychlorinated biphenyls interfere with androgen-induced transcriptional activation and hormone binding.

    Portigal CL, Cowell SP, Fedoruk MN, Butler CM, Rennie PS, Nelson CC.

    Toxicol Appl Pharmacol. 2002 Mar 15;179(3):185-94.PMID: 11906248 [PubMed - indexed for MEDLINE]Related articles

    10.

    Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

    Livak KJ, Schmittgen TD.

    Methods. 2001 Dec;25(4):402-8.PMID: 11846609 [PubMed - indexed for MEDLINE]Related articles

    11.

    Understanding the human health effects of chemical mixtures.

    Carpenter DO, Arcaro K, Spink DC.

    Environ Health Perspect. 2002 Feb;110 Suppl 1:25-42. Review.PMID: 11834461 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Peptide mimetic HIV protease inhibitors are ligands for the orphan receptor SXR.

    Dussault I, Lin M, Hollister K, Wang EH, Synold TW, Forman BM.

    J Biol Chem. 2001 Sep 7;276(36):33309-12. Epub 2001 Jul 20.PMID: 11466304 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Orphan nuclear receptors: the exotics of xenobiotics.

    Xie W, Evans RM.

    J Biol Chem. 2001 Oct 12;276(41):37739-42. Epub 2001 Jul 17. Review. No abstract available. PMID: 11459851 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    A comparison of aroclor 1254-induced and uninduced rat liver microsomes to human liver microsomes in phenytoin O-deethylation, coumarin 7-hydroxylation, tolbutamide 4-hydroxylation, S-mephenytoin 4'-hydroxylation, chloroxazone 6-hydroxylation and testosterone 6beta-hydroxylation.

    Easterbrook J, Fackett D, Li AP.

    Chem Biol Interact. 2001 May 16;134(3):243-9.PMID: 11336973 [PubMed - indexed for MEDLINE]Related articles

    15.

    Effect of highly bioaccumulated polychlorinated biphenyl congeners on estrogen and androgen receptor activity.

    Bonefeld-Jørgensen EC, Andersen HR, Rasmussen TH, Vinggaard AM.

    Toxicology. 2001 Feb 14;158(3):141-53.PMID: 11275356 [PubMed - indexed for MEDLINE]Related articles

    16.

    The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity.

    Staudinger JL, Goodwin B, Jones SA, Hawkins-Brown D, MacKenzie KI, LaTour A, Liu Y, Klaassen CD, Brown KK, Reinhard J, Willson TM, Koller BH, Kliewer SA.

    Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3369-74.PMID: 11248085 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Production of DNA strand breaks in vitro and reactive oxygen species in vitro and in HL-60 cells by PCB metabolites.

    Srinivasan A, Lehmler HJ, Robertson LW, Ludewig G.

    Toxicol Sci. 2001 Mar;60(1):92-102.PMID: 11222876 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.

    Xie W, Barwick JL, Simon CM, Pierce AM, Safe S, Blumberg B, Guzelian PS, Evans RM.

    Genes Dev. 2000 Dec 1;14(23):3014-23.PMID: 11114890 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers.

    Schilter B, Andersen MR, Acharya C, Omiecinski CJ.

    J Pharmacol Exp Ther. 2000 Sep;294(3):916-22.PMID: 10945841 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Humanized xenobiotic response in mice expressing nuclear receptor SXR.

    Xie W, Barwick JL, Downes M, Blumberg B, Simon CM, Nelson MC, Neuschwander-Tetri BA, Brunt EM, Guzelian PS, Evans RM.

    Nature. 2000 Jul 27;406(6794):435-9.PMID: 10935643 [PubMed - indexed for MEDLINE]Related articles

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