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    Results: 1 to 20 of 174

    1.

    Approaches to developing alternative and predictive toxicology based on PBPK/PD and QSAR modeling.

    Yang RS, Thomas RS, Gustafson DL, Campain J, Benjamin SA, Verhaar HJ, Mumtaz MM.

    Environ Health Perspect. 1998 Dec;106 Suppl 6:1385-93. Review.PMID: 9860897 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The use of physiologically-based pharmacokinetic/pharmacodynamic dosimetry models for chemical mixtures.

    Yang RS, el-Masri HA, Thomas RS, Constan AA.

    Toxicol Lett. 1995 Dec;82-83:497-504. Review.PMID: 8597101 [PubMed - indexed for MEDLINE]Related articles

    3.

    Physiologically based pharmacokinetic/pharmacodynamic modeling of chemical mixtures and possible applications in risk assessment.

    el-Masri HA, Thomas RS, Benjamin SA, Yang RS.

    Toxicology. 1995 Dec 28;105(2-3):275-82.PMID: 8571364 [PubMed - indexed for MEDLINE]Related articles

    4.

    The application of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling for exploring risk assessment approaches of chemical mixtures.

    Yang RS, el-Masri HA, Thomas RS, Constan AA, Tessari JD.

    Toxicol Lett. 1995 Sep;79(1-3):193-200. Review.PMID: 7570656 [PubMed - indexed for MEDLINE]Related articles

    5.

    Application of biologically based computer modeling to simple or complex mixtures.

    Liao KH, Dobrev ID, Dennison JE Jr, Andersen ME, Reisfeld B, Reardon KF, Campain JA, Wei W, Klein MT, Quann RJ, Yang RS.

    Environ Health Perspect. 2002 Dec;110 Suppl 6:957-63. Review.PMID: 12634125 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Prediction of rodent carcinogenic potential of naturally occurring chemicals in the human diet using high-throughput QSAR predictive modeling.

    Valerio LG Jr, Arvidson KB, Chanderbhan RF, Contrera JF.

    Toxicol Appl Pharmacol. 2007 Jul 1;222(1):1-16. Epub 2007 Mar 24.PMID: 17482223 [PubMed - indexed for MEDLINE]Related articles

    7.

    Integrated approaches for the analysis of toxicologic interactions of chemical mixtures.

    el-Masri HA, Reardon KF, Yang RS.

    Crit Rev Toxicol. 1997 Mar;27(2):175-97. Review.PMID: 9099518 [PubMed - indexed for MEDLINE]Related articles

    8.

    Integration of QSAR and in vitro toxicology.

    Barratt MD.

    Environ Health Perspect. 1998 Apr;106 Suppl 2:459-65.PMID: 9599692 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    A proposed approach to study the toxicology of complex mixtures of petroleum products: the integrated use of QSAR, lumping analysis and PBPK/PD modeling.

    Verhaar HJ, Morroni JR, Reardon KF, Hays SM, Gaver DP Jr, Carpenter RL, Yang RS.

    Environ Health Perspect. 1997 Feb;105 Suppl 1:179-95. Review.PMID: 9114286 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Development of physiologically based pharmacokinetic and physiologically based pharmacodynamic models for applications in toxicology and risk assessment.

    Andersen ME.

    Toxicol Lett. 1995 Sep;79(1-3):35-44. Review.PMID: 7570672 [PubMed - indexed for MEDLINE]Related articles

    11.

    NTP technical report on the toxicology and carcinogenesis studies of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague-Dawley rats (Gavage studies).

    National Toxicology Program.

    Natl Toxicol Program Tech Rep Ser. 2006 May;(529):4-168.PMID: 16835634 [PubMed - indexed for MEDLINE]Related articles

    12.

    Application of physiologically based pharmacokinetic modelling to combination toxicology.

    Simmons JE.

    Food Chem Toxicol. 1996 Nov-Dec;34(11-12):1067-73. Review.PMID: 9119317 [PubMed - indexed for MEDLINE]Related articles

    13.

    Quantitative structure-pharmacokinetic relationship modelling.

    Fouchécourt MO, Béliveau M, Krishnan K.

    Sci Total Environ. 2001 Jul 2;274(1-3):125-35.PMID: 11453289 [PubMed - indexed for MEDLINE]Related articles

    14.

    Use of cell viability assay data improves the prediction accuracy of conventional quantitative structure-activity relationship models of animal carcinogenicity.

    Zhu H, Rusyn I, Richard A, Tropsha A.

    Environ Health Perspect. 2008 Apr;116(4):506-13.PMID: 18414635 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    A novel two-step hierarchical quantitative structure-activity relationship modeling work flow for predicting acute toxicity of chemicals in rodents.

    Zhu H, Ye L, Richard A, Golbraikh A, Wright FA, Rusyn I, Tropsha A.

    Environ Health Perspect. 2009 Aug;117(8):1257-64. Epub 2009 Apr 3.PMID: 19672406 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    PBPK models in risk assessment--A focus on chloroprene.

    DeWoskin RS.

    Chem Biol Interact. 2007 Mar 20;166(1-3):352-9. Epub 2007 Feb 8.PMID: 17324392 [PubMed - indexed for MEDLINE]Related articles

    17.

    Current approaches toward chemical mixture studies at the National Institute of Environmental Health Sciences and the U.S. National Toxicology Program.

    Bucher JR, Lucier G.

    Environ Health Perspect. 1998 Dec;106 Suppl 6:1295-8. Review.PMID: 9860884 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    NTP technical report on the toxicology and carcinogenesis studies of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (CAS No. 1746-01-6) in female Harlan Sprague-Dawley rats (Gavage Studies).

    National Toxicology Program.

    Natl Toxicol Program Tech Rep Ser. 2006 Apr;(521):4-232.PMID: 16835633 [PubMed - indexed for MEDLINE]Related articles

    19.

    Extrapolating the future: research trends in modeling.

    Menzel DB.

    Toxicol Lett. 1995 Sep;79(1-3):299-303. Review.PMID: 7570670 [PubMed - indexed for MEDLINE]Related articles

    20.

    NTP toxicology and carcinogenesis studies of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague-Dawley rats (Gavage Studies).

    National Toxicology Program.

    Natl Toxicol Program Tech Rep Ser. 2006 Jan;(520):4-246.PMID: 16628245 [PubMed - indexed for MEDLINE]Related articles

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