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    Results: 1 to 20 of 104

    1.

    A toxicological basis to derive a generic interspecies uncertainty factor.

    Calabrese EJ, Baldwin LA.

    Environ Health Perspect. 1994 Jan;102(1):14-7.PMID: 9721264 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The application of non-default uncertainty factors in the U.S. EPA's Integrated Risk Information System (IRIS). Part I: UF(L), UF(S), and "other uncertainty factors".

    Stedeford T, Zhao QJ, Dourson ML, Banasik M, Hsu CH.

    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2007 Jul-Sep;25(3):245-79. Review.PMID: 17763048 [PubMed - indexed for MEDLINE]Related articles

    3.

    Time extrapolation and interspecies extrapolation for locally acting substances in case of limited toxicological data.

    Kalberlah F, Föst U, Schneider K.

    Ann Occup Hyg. 2002 Mar;46(2):175-85.PMID: 12074027 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Lack of total independence of uncertainty factors (UFs): implications for the size of the total uncertainty factor.

    Calabrese EJ, Gilbert CE.

    Regul Toxicol Pharmacol. 1993 Feb;17(1):44-51.PMID: 8441828 [PubMed - indexed for MEDLINE]Related articles

    5.

    Utilizing uncertainty factors in minimal risk levels derivation.

    Pohl HR, Abadin HG.

    Regul Toxicol Pharmacol. 1995 Oct;22(2):180-8. Review.PMID: 8577953 [PubMed - indexed for MEDLINE]Related articles

    6.

    Precision of estimates of an ADI (or TDI or PTWI).

    Speijers GJ.

    Regul Toxicol Pharmacol. 1999 Oct;30(2 Pt 2):S87-93. Review.PMID: 10597619 [PubMed - indexed for MEDLINE]Related articles

    7.

    Allometric principles for interspecies extrapolation in toxicological risk assessment--empirical investigations.

    Schneider K, Oltmanns J, Hassauer M.

    Regul Toxicol Pharmacol. 2004 Jun;39(3):334-47.PMID: 15135212 [PubMed - indexed for MEDLINE]Related articles

    8.

    Deriving a data-based interspecies assessment factor using the NOAEL and the benchmark dose approach.

    Bokkers BG, Slob W.

    Crit Rev Toxicol. 2007 Jun;37(5):355-73. Review.PMID: 17612951 [PubMed - indexed for MEDLINE]Related articles

    9.

    On the application of loss functions in determining assessment factors for ecological risk.

    Hickey GL, Craig PS, Hart A.

    Ecotoxicol Environ Saf. 2009 Feb;72(2):293-300. Epub 2008 Aug 8.PMID: 18691758 [PubMed - indexed for MEDLINE]Related articles

    10.

    Prediction of ecological no-effect concentrations for initial risk assessment: combining substance-specific data and database information.

    Roelofs W, Huijbregts MA, Jager T, Ragas AM.

    Environ Toxicol Chem. 2003 Jun;22(6):1387-93.PMID: 12785598 [PubMed - indexed for MEDLINE]Related articles

    11.

    Determination of a site-specific reference dose for methylmercury for fish-eating populations.

    Shipp AM, Gentry PR, Lawrence G, Van Landingham C, Covington T, Clewell HJ, Gribben K, Crump K.

    Toxicol Ind Health. 2000 Nov;16(9-10):335-438. Review.PMID: 11762928 [PubMed - indexed for MEDLINE]Related articles

    12.

    Assessing the risks of exposures to multiple chemicals with a common mechanism of toxicity: how to cumulate?

    Wilkinson CF, Christoph GR, Julien E, Kelley JM, Kronenberg J, McCarthy J, Reiss R.

    Regul Toxicol Pharmacol. 2000 Feb;31(1):30-43. Review.PMID: 10715222 [PubMed - indexed for MEDLINE]Related articles

    13.

    Characterization of the LOAEL-to-NOAEL uncertainty factor for mild adverse effects from acute inhalation exposures.

    Alexeeff GV, Broadwin R, Liaw J, Dawson SV.

    Regul Toxicol Pharmacol. 2002 Aug;36(1):96-105.PMID: 12383722 [PubMed - indexed for MEDLINE]Related articles

    14.

    Characterizing interspecies uncertainty using data from studies of anti-neoplastic agents in animals and humans.

    Price PS, Keenan RE, Swartout JC.

    Toxicol Appl Pharmacol. 2008 Nov 15;233(1):64-70. Epub 2008 Apr 16.PMID: 18514247 [PubMed - indexed for MEDLINE]Related articles

    15.

    Magnitude and mechanistic determinants of the interspecies toxicokinetic uncertainty factor for organic chemicals.

    Pelekis M, Krishnan K.

    Regul Toxicol Pharmacol. 2004 Dec;40(3):264-71.PMID: 15546680 [PubMed - indexed for MEDLINE]Related articles

    16.

    Development of an occupational exposure limit for n-propylbromide using benchmark dose methods.

    Stelljes ME, Wood RR.

    Regul Toxicol Pharmacol. 2004 Oct;40(2):136-50.PMID: 15450717 [PubMed - indexed for MEDLINE]Related articles

    17.

    Evolution of science-based uncertainty factors in noncancer risk assessment.

    Dourson ML, Felter SP, Robinson D.

    Regul Toxicol Pharmacol. 1996 Oct;24(2 Pt 1):108-20. Review.PMID: 8933624 [PubMed - indexed for MEDLINE]Related articles

    18.

    Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds.

    Pelekis M, Gephart LA, Lerman SE.

    Regul Toxicol Pharmacol. 2001 Feb;33(1):12-20.PMID: 11259175 [PubMed - indexed for MEDLINE]Related articles

    19.

    The use of toxicokinetic and toxicodynamic data in risk assessment: an international perspective.

    Gundert-Remy U, Sonich-Mullin C; IPCS Uncertainty and Variability Planning Workgroup and Drafting Group (International Program on Chemical Safety's).

    Sci Total Environ. 2002 Apr 8;288(1-2):3-11.PMID: 12013545 [PubMed - indexed for MEDLINE]Related articles

    20.

    Uncertainty factors for chemical risk assessment: interspecies differences in the in vivo pharmacokinetics and metabolism of human CYP1A2 substrates.

    Walton K, Dorne JL, Renwick AG.

    Food Chem Toxicol. 2001 Jul;39(7):667-80.PMID: 11397514 [PubMed - indexed for MEDLINE]Related articles

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