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    Results: 1 to 20 of 247

    1.

    Acute oral toxicity.

    Walum E.

    Environ Health Perspect. 1998 Apr;106 Suppl 2:497-503.PMID: 9599698 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Comparison of the up-and-down method and the fixed-dose procedure for acute oral toxicity testing.

    Yam J, Reer PJ, Bruce RD.

    Food Chem Toxicol. 1991 Apr;29(4):259-63.PMID: 2040488 [PubMed - indexed for MEDLINE]Related articles

    3.

    Dermal and inhalation acute toxic class methods: test procedures and biometric evaluations for the Globally Harmonized Classification System.

    Holzhütter HG, Genschow E, Diener W, Schlede E.

    Arch Toxicol. 2003 May;77(5):243-54. Epub 2003 Mar 12.PMID: 12734637 [PubMed - indexed for MEDLINE]Related articles

    4.

    Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

    EFSA GMO Panel Working Group on Animal Feeding Trials.

    Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. Epub 2008 Feb 13. Review.PMID: 18328408 [PubMed - indexed for MEDLINE]Related articles

    5.

    Alternative methods for the median lethal dose (LD(50)) test: the up-and-down procedure for acute oral toxicity.

    Rispin A, Farrar D, Margosches E, Gupta K, Stitzel K, Carr G, Greene M, Meyer W, McCall D.

    ILAR J. 2002;43(4):233-43.PMID: 12391399 [PubMed - indexed for MEDLINE]Related articles

    6.

    The biometric evaluation of the acute-toxic-class method (oral).

    Diener W, Siccha L, Mischke U, Kayser D, Schlede E.

    Arch Toxicol. 1994;68(10):599-610. Review.PMID: 7857199 [PubMed - indexed for MEDLINE]Related articles

    7.
    8.

    Strengths and limitations of using repeat-dose toxicity studies to predict effects on fertility.

    Dent MP.

    Regul Toxicol Pharmacol. 2007 Aug;48(3):241-58. Epub 2007 Apr 12.PMID: 17512650 [PubMed - indexed for MEDLINE]Related articles

    9.

    The dermal acute toxic class method: test procedures and biometric evaluations.

    Diener W, Kayser D, Schlede E.

    Arch Toxicol. 1998 Dec;72(12):751-62.PMID: 9950071 [PubMed - indexed for MEDLINE]Related articles

    10.

    A national validation study of the acute-toxic-class method--an alternative to the LD50 test.

    Schlede E, Mischke U, Roll R, Kayser D.

    Arch Toxicol. 1992;66(7):455-70. Review.PMID: 1444812 [PubMed - indexed for MEDLINE]Related articles

    11.

    Comparison of the up-and-down, conventional LD50, and fixed-dose acute toxicity procedures.

    Lipnick RL, Cotruvo JA, Hill RN, Bruce RD, Stitzel KA, Walker AP, Chu I, Goddard M, Segal L, Springer JA, et al.

    Food Chem Toxicol. 1995 Mar;33(3):223-31. Review.PMID: 7896233 [PubMed - indexed for MEDLINE]Related articles

    12.

    An up-and-down procedure for acute toxicity testing.

    Bruce RD.

    Fundam Appl Toxicol. 1985 Feb;5(1):151-7.PMID: 3987991 [PubMed - indexed for MEDLINE]Related articles

    13.

    The international validation of a fixed-dose procedure as an alternative to the classical LD50 test.

    van den Heuvel MJ, Clark DG, Fielder RJ, Koundakjian PP, Oliver GJ, Pelling D, Tomlinson NJ, Walker AP.

    Food Chem Toxicol. 1990 Jul;28(7):469-82.PMID: 2210519 [PubMed - indexed for MEDLINE]Related articles

    14.

    Comparison of five methods for the determination of lethal dose in acute toxicity studies.

    Paumgartten FJ, Presgrave OA, Menezes MA, Fingola FF, Freitas JC, Carvalho RR, Cunha FQ.

    Braz J Med Biol Res. 1989;22(8):987-91.PMID: 2633852 [PubMed - indexed for MEDLINE]Related articles

    15.

    Reduction of animal use with improved procedure for acute tolerance assessment.

    Fabian R, Fetrow N, Greener Y, Zelinger D, Olson H, Dean J.

    Regul Toxicol Pharmacol. 1993 Oct;18(2):206-13.PMID: 8278642 [PubMed - indexed for MEDLINE]Related articles

    16.

    A simple method for screening assessment of acute toxicity of chemicals.

    Yamanaka S, Hashimoto M, Tobe M, Kobayashi K, Sekizawa J, Nishimura M.

    Arch Toxicol. 1990;64(4):262-8.PMID: 2386428 [PubMed - indexed for MEDLINE]Related articles

    17.

    The fixed-dose procedure and the acute-toxic-class method: a mathematical comparison.

    Stallard N, Whitehead A.

    Hum Exp Toxicol. 1995 Dec;14(12):974-90.PMID: 8962748 [PubMed - indexed for MEDLINE]Related articles

    19.

    The integrated acute systemic toxicity project (ACuteTox) for the optimisation and validation of alternative in vitro tests.

    Clemedson C, Kolman A, Forsby A.

    Altern Lab Anim. 2007 Mar;35(1):33-8.PMID: 17411349 [PubMed - indexed for MEDLINE]Related articles

    20.

    Oral acute toxic class method: a successful alternative to the oral LD50 test.

    Schlede E, Genschow E, Spielmann H, Stropp G, Kayser D.

    Regul Toxicol Pharmacol. 2005 Jun;42(1):15-23. Epub 2005 Apr 8.PMID: 15896439 [PubMed - indexed for MEDLINE]Related articles

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