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Alternative tests: carcinogenesis as an example.

Schwetz B, Gaylor D.

Environ Health Perspect. 1998 Apr;106 Suppl 2:467-71.PMID: 9599693 [PubMed - indexed for MEDLINE]Related articlesFree article

New directions for predicting carcinogenesis.

Schwetz B, Gaylor D.

Mol Carcinog. 1997 Nov;20(3):275-9. Review.PMID: 9397187 [PubMed - indexed for MEDLINE]Related articles

A perspective on current and future uses of alternative models for carcinogenicity testing.

Goodman JI.

Toxicol Pathol. 2001;29 Suppl:173-6. Review.PMID: 11695554 [PubMed - indexed for MEDLINE]Related articles

Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection.

Rhomberg LR, Baetcke K, Blancato J, Bus J, Cohen S, Conolly R, Dixit R, Doe J, Ekelman K, Fenner-Crisp P, Harvey P, Hattis D, Jacobs A, Jacobson-Kram D, Lewandowski T, Liteplo R, Pelkonen O, Rice J, Somers D, Turturro A, West W, Olin S.

Crit Rev Toxicol. 2007;37(9):729-837. Review.PMID: 17957539 [PubMed - indexed for MEDLINE]Related articles

Are tumor incidence rates from chronic bioassays telling us what we need to know about carcinogens?

Gaylor DW.

Regul Toxicol Pharmacol. 2005 Mar;41(2):128-33. Epub 2004 Dec 19.PMID: 15698536 [PubMed - indexed for MEDLINE]Related articles

NTP technical report on the toxicology and carcinogenesis studies of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (CAS No. 1746-01-6) in female Harlan Sprague-Dawley rats (Gavage Studies).

National Toxicology Program.

Natl Toxicol Program Tech Rep Ser. 2006 Apr;(521):4-232.PMID: 16835633 [PubMed - indexed for MEDLINE]Related articles

Toxicology and Carcinogenesis Studies of 5,5-Diphenylhydantoin (CAS No. 57-41-0) (Phenytoin) in F344/N Rats and B6C3F1 Mice (Feed Studies).

National Toxicology Program.

Natl Toxicol Program Tech Rep Ser. 1993 Nov;404:1-303.PMID: 12621514 [PubMed - as supplied by publisher]Related articlesFree article

Background and framework for ILSI's collaborative evaluation program on alternative models for carcinogenicity assessment. International Life Sciences Institute.

Robinson DE, MacDonald JS.

Toxicol Pathol. 2001;29 Suppl:13-9. Review.PMID: 11695549 [PubMed - indexed for MEDLINE]Related articles

Chronic inhalation toxicity and carcinogenicity testing of respirable fibrous particles. Workshop report.

Vu V, Barrett JC, Roycroft J, Schuman L, Dankovic D, Bbaro P, Martonen T, Pepelko W, Lai D.

Regul Toxicol Pharmacol. 1996 Dec;24(3):202-12. Review.PMID: 8975745 [PubMed - indexed for MEDLINE]Related articles

Use of transgenic animals for carcinogenicity testing: considerations and implications for risk assessment.

Gulezian D, Jacobson-Kram D, McCullough CB, Olson H, Recio L, Robinson D, Storer R, Tennant R, Ward JM, Neumann DA.

Toxicol Pathol. 2000 May-Jun;28(3):482-99. Review.PMID: 10862569 [PubMed - indexed for MEDLINE]Related articles

Toxicology and carcinogenesis studies of methacrylonitrile (CAS No. 126-98-7) in F344/N rats and B6C3F1 mice (gavage studies).

[No authors listed]

Natl Toxicol Program Tech Rep Ser. 2001 Nov;(497):1-225.PMID: 11803703 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of the Tg.AC transgenic mouse assay for testing the human carcinogenic potential of pharmaceuticals--practical pointers, mechanistic clues, and new questions.

Sistare FD, Thompson KL, Honchel R, DeGeorge J.

Int J Toxicol. 2002 Jan-Feb;21(1):65-79. Review.PMID: 11936901 [PubMed - indexed for MEDLINE]Related articles

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens II. Further analysis of mammalian cell results, relative predictivity and tumour profiles.

Kirkland D, Aardema M, Müller L, Makoto H.

Mutat Res. 2006 Sep 19;608(1):29-42.PMID: 16769241 [PubMed - indexed for MEDLINE]Related articles

Review of alternative methods of carcinogenicity testing and evaluation of human pharmaceuticals.

Van Deun K, Van Cauteren H, Vandenberghe J, Canning M, Vanparys P, Coussement W.

Adverse Drug React Toxicol Rev. 1997 Nov;16(4):215-33. Review.PMID: 9608857 [PubMed - indexed for MEDLINE]Related articles

Chemically induced renal tubule tumors in the laboratory rat and mouse: review of the NCI/NTP database and categorization of renal carcinogens based on mechanistic information.

Lock EA, Hard GC.

Crit Rev Toxicol. 2004 May-Jun;34(3):211-99. Review.PMID: 15239388 [PubMed - indexed for MEDLINE]Related articles

NTP toxicology and carcinogenesis studies of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague-Dawley rats (Gavage Studies).

National Toxicology Program.

Natl Toxicol Program Tech Rep Ser. 2006 Jan;(520):4-246.PMID: 16628245 [PubMed - indexed for MEDLINE]Related articles

NTP technical report on the toxicology and carcinogenesis studies of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague-Dawley rats (Gavage studies).

National Toxicology Program.

Natl Toxicol Program Tech Rep Ser. 2006 May;(529):4-168.PMID: 16835634 [PubMed - indexed for MEDLINE]Related articles

Assessment of human cancer risk: challenges for alternative approaches.

Omenn GS.

Toxicol Pathol. 2001;29 Suppl:5-12. Review.PMID: 11695561 [PubMed - indexed for MEDLINE]Related articles

Conflicting views on chemical carcinogenesis arising from the design and evaluation of rodent carcinogenicity studies.

Melnick RL, Thayer KA, Bucher JR.

Environ Health Perspect. 2008 Jan;116(1):130-5.PMID: 18197312 [PubMed - indexed for MEDLINE]Related articlesFree article

NTP toxicology and carcinogenesis studies of triethanolamine (Cas No. 102-71-6) in B6C3F1 mice (dermal studies).

National Toxicology Program, Public Health Service, National Institutes of Health, US Department of Health and Human Services.

Natl Toxicol Program Tech Rep Ser. 2004 May;(518):5-163.PMID: 15213765 [PubMed - indexed for MEDLINE]Related articlesFree article