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Integration of QSAR and in vitro toxicology.
Barratt MD.
Environ Health Perspect. 1998 Apr;106 Suppl 2:459-65.PMID: 9599692 [PubMed - indexed for MEDLINE]Related articlesFree article
Integrating computer prediction systems with in vitro methods towards a better understanding of toxicology.
Toxicol Lett. 1998 Dec 28;102-103:617-21.PMID: 10022323 [PubMed - indexed for MEDLINE]Related articles
Promises and pitfalls of quantitative structure-activity relationship approaches for predicting metabolism and toxicity.
Zvinavashe E, Murk AJ, Rietjens IM.
Chem Res Toxicol. 2008 Dec;21(12):2229-36. Review.PMID: 19548346 [PubMed - indexed for MEDLINE]Related articles
On the nature, evolution and future of quantitative structure-activity relationships (QSAR) in toxicology.
Veith GD.
SAR QSAR Environ Res. 2004 Oct-Dec;15(5-6):323-30.PMID: 15669692 [PubMed - indexed for MEDLINE]Related articles
Approaches to developing alternative and predictive toxicology based on PBPK/PD and QSAR modeling.
Yang RS, Thomas RS, Gustafson DL, Campain J, Benjamin SA, Verhaar HJ, Mumtaz MM.
Environ Health Perspect. 1998 Dec;106 Suppl 6:1385-93. Review.PMID: 9860897 [PubMed - indexed for MEDLINE]Related articlesFree article
Prediction of rodent carcinogenic potential of naturally occurring chemicals in the human diet using high-throughput QSAR predictive modeling.
Valerio LG Jr, Arvidson KB, Chanderbhan RF, Contrera JF.
Toxicol Appl Pharmacol. 2007 Jul 1;222(1):1-16. Epub 2007 Mar 24.PMID: 17482223 [PubMed - indexed for MEDLINE]Related articles
Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
EFSA GMO Panel Working Group on Animal Feeding Trials.
Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. Epub 2008 Feb 13. Review.PMID: 18328408 [PubMed - indexed for MEDLINE]Related articles
Alternative models for toxicity testing of xenobiotics.
Kniewald J, Kmetic I, Gaurina-Srcek V, Kniewald Z.
Arh Hig Rada Toksikol. 2005 Jun;56(2):195-204.PMID: 15968836 [PubMed - indexed for MEDLINE]Related articles
TestSmart-high production volume chemicals: an approach to implementing alternatives into regulatory toxicology.
Green S, Goldberg A, Zurlo J.
Toxicol Sci. 2001 Sep;63(1):6-14.PMID: 11509738 [PubMed - indexed for MEDLINE]Related articlesFree article
QSAR models for predicting the acute toxicity of selected organic chemicals with diverse structures to aquatic non-vertebrates and humans.
Calleja MC, Geladi P, Persoone G.
SAR QSAR Environ Res. 1994;2(3):193-234.PMID: 8790646 [PubMed - indexed for MEDLINE]Related articles
Alternative test methods in inhalation toxicology: challenges and opportunities.
Costa DL.
Exp Toxicol Pathol. 2008 Jun;60(2-3):105-9. Epub 2008 May 16.PMID: 18486462 [PubMed - indexed for MEDLINE]Related articles
Survey of the QSAR and in vitro approaches for developing non-animal methods to supersede the in vivo LD50 test.
Phillips JC, Gibson WB, Yam J, Alden CL, Hard GC.
Food Chem Toxicol. 1990 May;28(5):375-94. Review.PMID: 2199353 [PubMed - indexed for MEDLINE]Related articles
Assessment of the eye irritating properties of chemicals by applying alternatives to the Draize rabbit eye test: the use of QSARs and in vitro tests for the classification of eye irritation.
Gerner I, Liebsch M, Spielmann H.
Altern Lab Anim. 2005 Jun;33(3):215-37. Review.PMID: 16180977 [PubMed - indexed for MEDLINE]Related articles
Predicting modes of toxic action from chemical structure: an overview.
Bradbury SP.
SAR QSAR Environ Res. 1994;2(1-2):89-104. Review.PMID: 8790641 [PubMed - indexed for MEDLINE]Related articles
Currently available in vitro methods used in the regulatory toxicology.
Liebsch M, Spielmann H.
Toxicol Lett. 2002 Feb 28;127(1-3):127-34. Review.PMID: 12052650 [PubMed - indexed for MEDLINE]Related articles
13th Meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): validation and acute toxicity testing.
Curren R, Bruner L, Goldberg A, Walum E.
Environ Health Perspect. 1998 Apr;106 Suppl 2:419-25.PMID: 9599688 [PubMed - indexed for MEDLINE]Related articlesFree article
Mechanistic applicability domains for nonanimal-based prediction of toxicological end points: general principles and application to reactive toxicity.
Aptula AO, Roberts DW.
Chem Res Toxicol. 2006 Aug;19(8):1097-105.PMID: 16918251 [PubMed - indexed for MEDLINE]Related articles
Computer-modeling-based QSARs for analyzing experimental data on biotransformation and toxicity.
Soffers AE, Boersma MG, Vaes WH, Vervoort J, Tyrakowska B, Hermens JL, Rietjens IM.
Toxicol In Vitro. 2001 Aug-Oct;15(4-5):539-51. Review.PMID: 11566589 [PubMed - indexed for MEDLINE]Related articles
Alternative methods for developmental toxicity testing.
Piersma AH.
Basic Clin Pharmacol Toxicol. 2006 May;98(5):427-31. Review.PMID: 16635099 [PubMed - indexed for MEDLINE]Related articles
An alternative approach for the safety evaluation of new and existing chemicals, an exercise in integrated testing.
Gubbels-van Hal WM, Blaauboer BJ, Barentsen HM, Hoitink MA, Meerts IA, van der Hoeven JC.
Regul Toxicol Pharmacol. 2005 Aug;42(3):284-95.PMID: 15979772 [PubMed - indexed for MEDLINE]Related articles
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