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Mechanistic approaches and the development of alternative toxicity test methods.

Balls M.

Environ Health Perspect. 1998 Apr;106 Suppl 2:453-7.PMID: 9599691 [PubMed - indexed for MEDLINE]Related articlesFree article

Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH).

Lilienblum W, Dekant W, Foth H, Gebel T, Hengstler JG, Kahl R, Kramer PJ, Schweinfurth H, Wollin KM.

Arch Toxicol. 2008 Apr;82(4):211-36. Epub 2008 Mar 6.PMID: 18322675 [PubMed - indexed for MEDLINE]Related articles

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials.

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. Epub 2008 Feb 13. Review.PMID: 18328408 [PubMed - indexed for MEDLINE]Related articles

Introduction and summary of the 13th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies.

Stokes WS, Marafante E.

Environ Health Perspect. 1998 Apr;106 Suppl 2:405-12.PMID: 9599686 [PubMed - indexed for MEDLINE]Related articlesFree article

13th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies and conceptual issues.

Blaauboer BJ, Balls M, Barratt M, Casati S, Coecke S, Mohamed MK, Moore J, Rall D, Smith KR, Tennant R, Schwetz BA, Stokes WS, Younes M.

Environ Health Perspect. 1998 Apr;106 Suppl 2:413-8.PMID: 9599687 [PubMed - indexed for MEDLINE]Related articlesFree article

Future improvements: replacement in vitro methods.

Balls M.

ILAR J. 2002;43 Suppl:S69-73. Review.PMID: 12388855 [PubMed - indexed for MEDLINE]Related articles

13th Meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): validation and acute toxicity testing.

Curren R, Bruner L, Goldberg A, Walum E.

Environ Health Perspect. 1998 Apr;106 Suppl 2:419-25.PMID: 9599688 [PubMed - indexed for MEDLINE]Related articlesFree article

Validation of alternative methods for toxicity testing.

Bruner LH, Carr GJ, Curren RD, Chamberlain M.

Environ Health Perspect. 1998 Apr;106 Suppl 2:477-84.PMID: 9599695 [PubMed - indexed for MEDLINE]Related articlesFree article

Alternative test methods in inhalation toxicology: challenges and opportunities.

Costa DL.

Exp Toxicol Pathol. 2008 Jun;60(2-3):105-9. Epub 2008 May 16.PMID: 18486462 [PubMed - indexed for MEDLINE]Related articles

Testing and assessment strategies, including alternative and new approaches.

Meyer O.

Toxicol Lett. 2003 Apr 11;140-141:21-30. Review.PMID: 12676447 [PubMed - indexed for MEDLINE]Related articles

Use of the dog as non-rodent test species in the safety testing schedule associated with the registration of crop and plant protection products (pesticides): present status.

Box RJ, Spielmann H.

Arch Toxicol. 2005 Nov;79(11):615-26. Epub 2005 Jun 7.PMID: 15940470 [PubMed - indexed for MEDLINE]Related articles

Integration of QSAR and in vitro toxicology.

Barratt MD.

Environ Health Perspect. 1998 Apr;106 Suppl 2:459-65.PMID: 9599692 [PubMed - indexed for MEDLINE]Related articlesFree article

13th Meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies for organ toxicity.

Spielmann H, Bochkov NP, Costa L, Gribaldo L, Guillouzo A, Heindel JJ, Karol M, Parchment R, Pfaller W, Peraita PP, Zacharewski T.

Environ Health Perspect. 1998 Apr;106 Suppl 2:427-39.PMID: 9599689 [PubMed - indexed for MEDLINE]Related articlesFree article

13th Meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies for ecotoxicity.

Walker C, Kaiser K, Klein W, Lagadic L, Peakall D, Sheffield S, Soldan T, Yasuno M.

Environ Health Perspect. 1998 Apr;106 Suppl 2:441-51.PMID: 9599690 [PubMed - indexed for MEDLINE]Related articlesFree article

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.

Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P.

Mutat Res. 2007 Mar 30;628(1):31-55. Epub 2007 Jan 13.PMID: 17293159 [PubMed - indexed for MEDLINE]Related articles

Status and prospects of in vitro tests in risk assessment.

Louekari K.

Altern Lab Anim. 2004 Oct;32(4):431-5. Review.PMID: 15651929 [PubMed - indexed for MEDLINE]Related articles

In vitro alternatives for ocular irritation.

Curren RD, Harbell JW.

Environ Health Perspect. 1998 Apr;106 Suppl 2:485-92.PMID: 9599696 [PubMed - indexed for MEDLINE]Related articlesFree article

Implementation of the 3Rs (refinement, reduction, and replacement): validation and regulatory acceptance considerations for alternative toxicological test methods.

Schechtman LM.

ILAR J. 2002;43 Suppl:S85-94. Review.PMID: 12388858 [PubMed - indexed for MEDLINE]Related articles

Ecotoxicity testing: science, politics and ethics.

Walker CH.

Altern Lab Anim. 2008 Feb;36(1):103-12.PMID: 18333718 [PubMed - indexed for MEDLINE]Related articles

Humane endpoints for laboratory animals used in regulatory testing.

Stokes WS.

ILAR J. 2002;43 Suppl:S31-8. Review.PMID: 12388849 [PubMed - indexed for MEDLINE]Related articles