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13th Meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): validation and acute toxicity testing.

Curren R, Bruner L, Goldberg A, Walum E.

Environ Health Perspect. 1998 Apr;106 Suppl 2:419-25.PMID: 9599688 [PubMed - indexed for MEDLINE]Related articlesFree article

Introduction and summary of the 13th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies.

Stokes WS, Marafante E.

Environ Health Perspect. 1998 Apr;106 Suppl 2:405-12.PMID: 9599686 [PubMed - indexed for MEDLINE]Related articlesFree article

Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH).

Lilienblum W, Dekant W, Foth H, Gebel T, Hengstler JG, Kahl R, Kramer PJ, Schweinfurth H, Wollin KM.

Arch Toxicol. 2008 Apr;82(4):211-36. Epub 2008 Mar 6.PMID: 18322675 [PubMed - indexed for MEDLINE]Related articles

13th Meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies for organ toxicity.

Spielmann H, Bochkov NP, Costa L, Gribaldo L, Guillouzo A, Heindel JJ, Karol M, Parchment R, Pfaller W, Peraita PP, Zacharewski T.

Environ Health Perspect. 1998 Apr;106 Suppl 2:427-39.PMID: 9599689 [PubMed - indexed for MEDLINE]Related articlesFree article

13th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies and conceptual issues.

Blaauboer BJ, Balls M, Barratt M, Casati S, Coecke S, Mohamed MK, Moore J, Rall D, Smith KR, Tennant R, Schwetz BA, Stokes WS, Younes M.

Environ Health Perspect. 1998 Apr;106 Suppl 2:413-8.PMID: 9599687 [PubMed - indexed for MEDLINE]Related articlesFree article

13th Meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies for ecotoxicity.

Walker C, Kaiser K, Klein W, Lagadic L, Peakall D, Sheffield S, Soldan T, Yasuno M.

Environ Health Perspect. 1998 Apr;106 Suppl 2:441-51.PMID: 9599690 [PubMed - indexed for MEDLINE]Related articlesFree article

Validation of alternative methods for toxicity testing.

Bruner LH, Carr GJ, Curren RD, Chamberlain M.

Environ Health Perspect. 1998 Apr;106 Suppl 2:477-84.PMID: 9599695 [PubMed - indexed for MEDLINE]Related articlesFree article

Alternatives to animal experimentation in basic research.

Gruber FP, Hartung T.

ALTEX. 2004;21 Suppl 1:3-31. Review.PMID: 15586255 [PubMed - indexed for MEDLINE]Related articles

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials.

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. Epub 2008 Feb 13. Review.PMID: 18328408 [PubMed - indexed for MEDLINE]Related articles

Acute systemic toxicity--prospects for tiered testing strategies.

Botham PA.

Toxicol In Vitro. 2004 Apr;18(2):227-30.PMID: 14757114 [PubMed - indexed for MEDLINE]Related articles

Acute systemic toxicity.

Botham PA.

ILAR J. 2002;43 Suppl:S27-30. Review.PMID: 12388848 [PubMed - indexed for MEDLINE]Related articles

TestSmart-high production volume chemicals: an approach to implementing alternatives into regulatory toxicology.

Green S, Goldberg A, Zurlo J.

Toxicol Sci. 2001 Sep;63(1):6-14.PMID: 11509738 [PubMed - indexed for MEDLINE]Related articlesFree article

Implementation of the 3Rs (refinement, reduction, and replacement): validation and regulatory acceptance considerations for alternative toxicological test methods.

Schechtman LM.

ILAR J. 2002;43 Suppl:S85-94. Review.PMID: 12388858 [PubMed - indexed for MEDLINE]Related articles

The ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity Function Test.

Spielmann H, Hoffmann S, Liebsch M, Botham P, Fentem JH, Eskes C, Roguet R, Cotovio J, Cole T, Worth A, Heylings J, Jones P, Robles C, Kandárová H, Gamer A, Remmele M, Curren R, Raabe H, Cockshott A, Gerner I, Zuang V.

Altern Lab Anim. 2007 Dec;35(6):559-601.PMID: 18186667 [PubMed - indexed for MEDLINE]Related articles

The in vitro skin irritation of chemicals: optimisation of the EPISKIN prediction model within the framework of the ECVAM validation process.

Cotovio J, Grandidier MH, Portes P, Roguet R, Rubinstenn G.

Altern Lab Anim. 2005 Aug;33(4):329-49.PMID: 16185103 [PubMed - indexed for MEDLINE]Related articles

An overview of structure-activity relationships as an alternative to testing in animals for carcinogenicity, mutagenicity, dermal and eye irritation, and acute oral toxicity.

Enslein K.

Toxicol Ind Health. 1988 Dec;4(4):479-98.PMID: 3188045 [PubMed - indexed for MEDLINE]Related articles

Mechanistic approaches and the development of alternative toxicity test methods.

Balls M.

Environ Health Perspect. 1998 Apr;106 Suppl 2:453-7.PMID: 9599691 [PubMed - indexed for MEDLINE]Related articlesFree article

Alternatives to animal testing: research, trends, validation, regulatory acceptance.

Huggins J.

ALTEX. 2003;20(Suppl 1):3-61. Review.PMID: 14671702 [PubMed - indexed for MEDLINE]Related articles

In vitro and human testing strategies for skin irritation.

Robinson MK, Osborne R, Perkins MA.

Ann N Y Acad Sci. 2000;919:192-204.PMID: 11083109 [PubMed - indexed for MEDLINE]Related articles

Use of the dog as non-rodent test species in the safety testing schedule associated with the registration of crop and plant protection products (pesticides): present status.

Box RJ, Spielmann H.

Arch Toxicol. 2005 Nov;79(11):615-26. Epub 2005 Jun 7.PMID: 15940470 [PubMed - indexed for MEDLINE]Related articles