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    Results: 1 to 20 of 107

    1.

    Estimating xenobiotic half-lives in humans from rat data: influence of log P.

    Sarver JG, White D, Erhardt P, Bachmann K.

    Environ Health Perspect. 1997 Nov;105(11):1204-9. Review.PMID: 9370523 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Scaling basic toxicokinetic parameters from rat to man.

    Bachmann K, Pardoe D, White D.

    Environ Health Perspect. 1996 Apr;104(4):400-7. Review.PMID: 8732950 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Application of simple mathematical expressions to relate the half-lives of xenobiotics in rats to values in humans.

    Ward KW, Erhardt P, Bachmann K.

    J Pharmacol Toxicol Methods. 2005 Jan-Feb;51(1):57-64.PMID: 15596115 [PubMed - indexed for MEDLINE]Related articles

    4.

    Predicting toxicokinetic parameters in humans from toxicokinetic data acquired from three small mammalian species.

    Bachmann K.

    J Appl Toxicol. 1989 Oct;9(5):331-8.PMID: 2592732 [PubMed - indexed for MEDLINE]Related articles

    5.

    Application of simple mathematical expressions to relate half-lives of drugs in mice to those in humans.

    Bachmann K, Chupka J, Erhardt P, White D.

    Drug Metab Lett. 2007 Apr;1(2):127-9.PMID: 19356031 [PubMed - indexed for MEDLINE]Related articles

    6.

    Prediction of vitreal half-life based on drug physicochemical properties: quantitative structure-pharmacokinetic relationships (QSPKR).

    Durairaj C, Shah JC, Senapati S, Kompella UB.

    Pharm Res. 2009 May;26(5):1236-60. Epub 2008 Oct 8.PMID: 18841448 [PubMed - indexed for MEDLINE]Related articles

    7.

    Application of a generic physiologically based pharmacokinetic model to the estimation of xenobiotic levels in rat plasma.

    Brightman FA, Leahy DE, Searle GE, Thomas S.

    Drug Metab Dispos. 2006 Jan;34(1):84-93. Epub 2005 Oct 12.PMID: 16221757 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Dosing via gavage or diet for reproduction studies: a pilot study using two fat-soluble compounds-hexachlorobenzene and aroclor 1254.

    Arnold DL, Bryce FR, Clegg DJ, Cherry W, Tanner JR, Hayward S.

    Food Chem Toxicol. 2000 Aug;38(8):697-706.PMID: 10908817 [PubMed - indexed for MEDLINE]Related articles

    9.

    Differences in pharmacokinetics between children and adults--II. Children's variability in drug elimination half-lives and in some parameters needed for physiologically-based pharmacokinetic modeling.

    Hattis D, Ginsberg G, Sonawane B, Smolenski S, Russ A, Kozlak M, Goble R.

    Risk Anal. 2003 Feb;23(1):117-42.PMID: 12635728 [PubMed - indexed for MEDLINE]Related articles

    10.

    Apparent half-lives of dioxins, furans, and polychlorinated biphenyls as a function of age, body fat, smoking status, and breast-feeding.

    Milbrath MO, Wenger Y, Chang CW, Emond C, Garabrant D, Gillespie BW, Jolliet O.

    Environ Health Perspect. 2009 Mar;117(3):417-25. Epub 2008 Oct 3.PMID: 19337517 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Allometric scaling of xenobiotic clearance: uncertainty versus universality.

    Hu TM, Hayton WL.

    AAPS PharmSci. 2001;3(4):E29.PMID: 12049492 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    QSAR approach to estimation of the distribution of xenobiotics and the target organ in the body.

    Tichý M.

    Drug Metabol Drug Interact. 1991;9(3-4):191-200.PMID: 1824075 [PubMed - indexed for MEDLINE]Related articles

    13.

    Half-lives of tetra-, penta-, hexa-, hepta-, and octachlorodibenzo-p-dioxin in rats, monkeys, and humans--a critical review.

    Geyer HJ, Schramm KW, Feicht EA, Behechti A, Steinberg C, Brüggemann R, Poiger H, Henkelmann B, Kettrup A.

    Chemosphere. 2002 Aug;48(6):631-44. Review.PMID: 12143938 [PubMed - indexed for MEDLINE]Related articles

    14.

    Relative lipid content as the sole mechanistic determinant of the adipose tissue:blood partition coefficients of highly lipophilic organic chemicals.

    Haddad S, Poulin P, Krishnan K.

    Chemosphere. 2000 Apr;40(8):839-43.PMID: 10718576 [PubMed - indexed for MEDLINE]Related articles

    15.

    Interspecies allometric analysis of the comparative pharmacokinetics of 44 drugs across veterinary and laboratory animal species.

    Riviere JE, Martin-Jimenez T, Sundlof SF, Craigmill AL.

    J Vet Pharmacol Ther. 1997 Dec;20(6):453-63. Review.PMID: 9430769 [PubMed - indexed for MEDLINE]Related articles

    16.

    Development of a population pharmacokinetic model for carbamazepine based on sparse therapeutic monitoring data from pediatric patients with epilepsy.

    Carlsson KC, Hoem NO, Glauser T, Vinks AA.

    Clin Ther. 2005 May;27(5):618-26.PMID: 15978311 [PubMed - indexed for MEDLINE]Related articles

    17.

    Interspecies scaling: predicting volumes, mean residence time and elimination half-life. Some suggestions.

    Mahmood I.

    J Pharm Pharmacol. 1998 May;50(5):493-9. Review.PMID: 9643442 [PubMed - indexed for MEDLINE]Related articles

    18.

    Prediction of human pharmacokinetics--evaluation of methods for prediction of volume of distribution.

    Fagerholm U.

    J Pharm Pharmacol. 2007 Sep;59(9):1181-90. Review.PMID: 17883888 [PubMed - indexed for MEDLINE]Related articles

    19.

    Tissue distribution and half-lives of individual polychlorinated biphenyls and serum levels of 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl in the rat.

    Oberg M, Sjödin A, Casabona H, Nordgren I, Klasson-Wehler E, Håkansson H.

    Toxicol Sci. 2002 Dec;70(2):171-82.PMID: 12441362 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Forecasting cephalosporin and monobactam antibiotic half-lives in humans from data collected in laboratory animals.

    Mordenti J.

    Antimicrob Agents Chemother. 1985 Jun;27(6):887-91.PMID: 3927836 [PubMed - indexed for MEDLINE]Related articlesFree article

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