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    Results: 1 to 20 of 150

    1.

    The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia.

    Smith MT.

    Environ Health Perspect. 1996 Dec;104 Suppl 6:1219-25. Review.PMID: 9118896 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo.

    Kolachana P, Subrahmanyam VV, Meyer KB, Zhang L, Smith MT.

    Cancer Res. 1993 Mar 1;53(5):1023-6.PMID: 8439949 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Characterization and mechanisms of chromosomal alterations induced by benzene in mice and humans.

    Eastmond DA, Schuler M, Frantz C, Chen H, Parks R, Wang L, Hasegawa L.

    Res Rep Health Eff Inst. 2001 Jun;(103):1-68; discussion 69-80.PMID: 11504146 [PubMed - indexed for MEDLINE]Related articles

    4.

    Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity.

    Smith MT, Yager JW, Steinmetz KL, Eastmond DA.

    Environ Health Perspect. 1989 Jul;82:23-9. Review.PMID: 2551665 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Effects of benzene metabolites on DNA cleavage mediated by human topoisomerase II alpha: 1,4-hydroquinone is a topoisomerase II poison.

    Lindsey RH Jr, Bender RP, Osheroff N.

    Chem Res Toxicol. 2005 Apr;18(4):761-70.PMID: 15833037 [PubMed - indexed for MEDLINE]Related articles

    6.

    Benzene induces gene-duplicating but not gene-inactivating mutations at the glycophorin A locus in exposed humans.

    Rothman N, Haas R, Hayes RB, Li GL, Wiemels J, Campleman S, Quintana PJ, Xi LJ, Dosemeci M, Titenko-Holland N, et al.

    Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):4069-73.PMID: 7732033 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene.

    Hutt AM, Kalf GF.

    Environ Health Perspect. 1996 Dec;104 Suppl 6:1265-9.PMID: 9118903 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Inhibition of human topoisomerase II in vitro by bioactive benzene metabolites.

    Frantz CE, Chen H, Eastmond DA.

    Environ Health Perspect. 1996 Dec;104 Suppl 6:1319-23.PMID: 9118913 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Topoisomerase II inhibition by myeloperoxidase-activated hydroquinone: a potential mechanism underlying the genotoxic and carcinogenic effects of benzene.

    Eastmond DA, Mondrala ST, Hasegawa L.

    Chem Biol Interact. 2005 May 30;153-154:207-16. Epub 2005 Apr 9.PMID: 15935818 [PubMed - indexed for MEDLINE]Related articles

    10.

    Topoisomerase inhibition by phenolic metabolites: a potential mechanism for benzene's clastogenic effects.

    Chen H, Eastmond DA.

    Carcinogenesis. 1995 Oct;16(10):2301-7.PMID: 7586126 [PubMed - indexed for MEDLINE]Related articles

    11.

    Induction of micronuclei and aneuploidy by the quinone-forming agents benzene and o-phenylphenol.

    Eastmond DA.

    Toxicol Lett. 1993 Apr;67(1-3):105-18. Review.PMID: 8451753 [PubMed - indexed for MEDLINE]Related articles

    12.

    Characterization of genetic instability in radiation- and benzene-induced murine acute leukemia.

    Rithidech K, Dunn JJ, Bond VP, Gordon CR, Cronkite EP.

    Mutat Res. 1999 Jul 16;428(1-2):33-9. Review.PMID: 10517976 [PubMed - indexed for MEDLINE]Related articles

    13.

    Cell-specific activation and detoxification of benzene metabolites in mouse and human bone marrow: identification of target cells and a potential role for modulation of apoptosis in benzene toxicity.

    Ross D, Siegel D, Schattenberg DG, Sun XM, Moran JL.

    Environ Health Perspect. 1996 Dec;104 Suppl 6:1177-82.PMID: 9118890 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Mechanism of benzene-induced hematotoxicity and leukemogenicity: current review with implication of microarray analyses.

    Hirabayashi Y, Yoon BI, Li GX, Kanno J, Inoue T.

    Toxicol Pathol. 2004 Jul-Aug;32 Suppl 2:12-6. Review.PMID: 15503659 [PubMed - indexed for MEDLINE]Related articles

    15.

    A perspective on benzene leukemogenesis.

    Snyder R, Kalf GF.

    Crit Rev Toxicol. 1994;24(3):177-209. Review.PMID: 7945890 [PubMed - indexed for MEDLINE]Related articles

    16.

    Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression.

    Faiola B, Fuller ES, Wong VA, Pluta L, Abernethy DJ, Rose J, Recio L.

    Stem Cells. 2004;22(5):750-8.PMID: 15342939 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Stimulation of topoisomerase II-mediated DNA cleavage by benzene metabolites.

    Lindsey RH, Bender RP, Osheroff N.

    Chem Biol Interact. 2005 May 30;153-154:197-205. Epub 2005 Apr 25.PMID: 15935817 [PubMed - indexed for MEDLINE]Related articles

    18.

    Potential role of free radicals in benzene-induced myelotoxicity and leukemia.

    Subrahmanyam VV, Ross D, Eastmond DA, Smith MT.

    Free Radic Biol Med. 1991;11(5):495-515. Review.PMID: 1769608 [PubMed - indexed for MEDLINE]Related articles

    19.

    DNA-protein cross-link levels in bone marrow cells of mice treated with benzene or trans,trans-muconaldehyde.

    Schoenfeld HA, Witz G.

    J Toxicol Environ Health A. 1999 Mar 26;56(6):379-95.PMID: 10096361 [PubMed - indexed for MEDLINE]Related articles

    20.

    Mechanistic considerations in benzene physiological model development.

    Medinsky MA, Kenyon EM, Seaton MJ, Schlosser PM.

    Environ Health Perspect. 1996 Dec;104 Suppl 6:1399-404. Review.PMID: 9118926 [PubMed - indexed for MEDLINE]Related articlesFree article

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