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    Results: 1 to 20 of 113

    1.

    Pharmacokinetics and molecular detoxication.

    Cashman JR, Perotti BY, Berkman CE, Lin J.

    Environ Health Perspect. 1996 Mar;104 Suppl 1:23-40. Review.PMID: 8722108 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Biotransformation of organophosphorus compounds.

    Jokanović M.

    Toxicology. 2001 Sep 25;166(3):139-60. Review.PMID: 11543910 [PubMed - indexed for MEDLINE]Related articles

    3.

    Sources, pathways, and relative risks of contaminants in surface water and groundwater: a perspective prepared for the Walkerton inquiry.

    Ritter L, Solomon K, Sibley P, Hall K, Keen P, Mattu G, Linton B.

    J Toxicol Environ Health A. 2002 Jan 11;65(1):1-142. Review.PMID: 11809004 [PubMed - indexed for MEDLINE]Related articles

    4.

    Incorporating human interindividual biotransformation variance in health risk assessment.

    Lipscomb JC, Kedderis GL.

    Sci Total Environ. 2002 Apr 8;288(1-2):13-21.PMID: 12013540 [PubMed - indexed for MEDLINE]Related articles

    5.

    Detoxication of paraoxon by rat liver homogenate and serum carboxylesterases and A-esterases.

    Tang J, Chambers JE.

    J Biochem Mol Toxicol. 1999;13(5):261-8.PMID: 10402560 [PubMed - indexed for MEDLINE]Related articles

    6.

    Human hepatic cell cultures: in vitro and in vivo drug metabolism.

    Gómez-Lechón MJ, Donato T, Ponsoda X, Castell JV.

    Altern Lab Anim. 2003 May-Jun;31(3):257-65.PMID: 15612868 [PubMed - indexed for MEDLINE]Related articles

    7.

    Risk management frameworks for human health and environmental risks.

    Jardine C, Hrudey S, Shortreed J, Craig L, Krewski D, Furgal C, McColl S.

    J Toxicol Environ Health B Crit Rev. 2003 Nov-Dec;6(6):569-720. Review.PMID: 14698953 [PubMed - indexed for MEDLINE]Related articles

    8.

    Applications of carboxylesterase activity in environmental monitoring and toxicity identification evaluations (TIEs).

    Wheelock CE, Phillips BM, Anderson BS, Miller JL, Miller MJ, Hammock BD.

    Rev Environ Contam Toxicol. 2008;195:117-78. Review.PMID: 18418956 [PubMed - indexed for MEDLINE]Related articles

    9.

    Cytochrome P450 catalysed insecticide metabolism: chemical and theoretical models.

    Keserü GM.

    Sci Prog. 1998;81 ( Pt 3):245-72. Review.PMID: 9800539 [PubMed - indexed for MEDLINE]Related articles

    10.

    Application of in vitro biotransformation data and pharmacokinetic modeling to risk assessment.

    Kedderis GL, Lipscomb JC.

    Toxicol Ind Health. 2001 Jun;17(5-10):315-21.PMID: 12539878 [PubMed - indexed for MEDLINE]Related articles

    11.

    Mechanistic aspects of organophosphorothionate toxicity in fish and humans.

    Vittozzi L, Fabrizi L, Di Consiglio E, Testai E.

    Environ Int. 2001 Jan;26(3):125-9.PMID: 11341695 [PubMed - indexed for MEDLINE]Related articles

    12.

    Mediation of pyrethroid insecticide toxicity to honey bees (Hymenoptera: Apidae) by cytochrome P450 monooxygenases.

    Johnson RM, Wen Z, Schuler MA, Berenbaum MR.

    J Econ Entomol. 2006 Aug;99(4):1046-50.PMID: 16937654 [PubMed - indexed for MEDLINE]Related articles

    13.

    Preclinical pharmacokinetics: an approach towards safer and efficacious drugs.

    Singh SS.

    Curr Drug Metab. 2006 Feb;7(2):165-82. Review.PMID: 16472106 [PubMed - indexed for MEDLINE]Related articles

    14.

    Human drug metabolism and the cytochromes P450: application and relevance of in vitro models.

    Venkatakrishnan K, Von Moltke LL, Greenblatt DJ.

    J Clin Pharmacol. 2001 Nov;41(11):1149-79. Review.PMID: 11697750 [PubMed - indexed for MEDLINE]Related articles

    15.

    Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition.

    Poulin P, Theil FP.

    J Pharm Sci. 2002 May;91(5):1358-70.PMID: 11977112 [PubMed - indexed for MEDLINE]Related articles

    16.

    Glutathione S-transferase conjugation of organophosphorus pesticides yields S-phospho-, S-aryl-, and S-alkylglutathione derivatives.

    Fujioka K, Casida JE.

    Chem Res Toxicol. 2007 Aug;20(8):1211-7. Epub 2007 Jul 21.PMID: 17645302 [PubMed - indexed for MEDLINE]Related articles

    17.

    An overview of human exposure modeling activities at the USEPA's National Exposure Research Laboratory.

    Furtaw EJ Jr.

    Toxicol Ind Health. 2001 Jun;17(5-10):302-14. Review.PMID: 12539877 [PubMed - indexed for MEDLINE]Related articles

    18.

    Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: evidence for its oxidative detoxication by human cytochromes P450.

    Miksanová M, Sulc M, Rýdlová H, Schmeiser HH, Frei E, Stiborová M.

    Chem Res Toxicol. 2004 May;17(5):663-71.PMID: 15144223 [PubMed - indexed for MEDLINE]Related articles

    19.

    Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds.

    Furlong CE.

    J Biochem Mol Toxicol. 2007;21(4):197-205. Review. Erratum in: J Biochem Mol Toxicol. 2007;21(5):323. PMID: 17936934 [PubMed - indexed for MEDLINE]Related articles

    20.

    Prediction of interindividual variation in drug plasma levels in vivo from individual enzyme kinetic data and physiologically based pharmacokinetic modeling.

    Bogaards JJ, Hissink EM, Briggs M, Weaver R, Jochemsen R, Jackson P, Bertrand M, van Bladeren PJ.

    Eur J Pharm Sci. 2000 Dec;12(2):117-24.PMID: 11102739 [PubMed - indexed for MEDLINE]Related articles

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