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    Results: 1 to 20 of 276

    1.

    Metabolism of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in isolated liver cells from guinea pig, hamster, mouse, and rat.

    Alexander J, Fossum BH, Holme JA.

    Environ Health Perspect. 1994 Oct;102 Suppl 6:109-14.PMID: 7889830 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Metabolism of the food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat and other rodents.

    Alexander J, Fossum BH, Reistad R, Holme JA.

    Princess Takamatsu Symp. 1995;23:113-22. Review.PMID: 8844802 [PubMed - indexed for MEDLINE]Related articles

    3.

    The metabolism and DNA binding of the cooked-food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in precision-cut rat liver slices.

    Connors MS, Malfatti MA, Felton JS.

    Chem Biol Interact. 1995 May 19;96(2):185-202.PMID: 7728907 [PubMed - indexed for MEDLINE]Related articles

    4.

    The role of sulfation and/or acetylation in the metabolism of the cooked-food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Salmonella typhimurium and isolated rat hepatocytes.

    Malfatti MA, Buonarati MH, Turteltaub KW, Shen NH, Felton JS.

    Chem Res Toxicol. 1994 Mar-Apr;7(2):139-47.PMID: 8199301 [PubMed - indexed for MEDLINE]Related articles

    5.

    Effect of glutathione depletion and inhibition of glucuronidation and sulfation on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism, PhIP-DNA adduct formation and unscheduled DNA synthesis in primary rat hepatocytes.

    Kaderlik KR, Mulder GJ, Shaddock JG, Casciano DA, Teitel CH, Kadlubar FF.

    Carcinogenesis. 1994 Aug;15(8):1711-6.PMID: 8055653 [PubMed - indexed for MEDLINE]Related articles

    6.

    Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2.

    Turesky RJ, Guengerich FP, Guillouzo A, Langouët S.

    Mutat Res. 2002 Sep 30;506-507:187-95.PMID: 12351158 [PubMed - indexed for MEDLINE]Related articles

    7.

    Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues.

    Kaderlik KR, Minchin RF, Mulder GJ, Ilett KF, Daugaard-Jenson M, Teitel CH, Kadlubar FF.

    Carcinogenesis. 1994 Aug;15(8):1703-9.PMID: 8055652 [PubMed - indexed for MEDLINE]Related articles

    8.

    Metabolites of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) in human urine after consumption of charbroiled or fried beef.

    Strickland PT, Qian Z, Friesen MD, Rothman N, Sinha R.

    Mutat Res. 2002 Sep 30;506-507:163-73. Review.PMID: 12351156 [PubMed - indexed for MEDLINE]Related articles

    9.

    Metabolic processing and disposition of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates.

    Snyderwine EG, Turesky RJ, Buonarati MH, Turteltaub KW, Adamson RH.

    Princess Takamatsu Symp. 1995;23:69-77.PMID: 8844797 [PubMed - indexed for MEDLINE]Related articles

    10.

    Metabolism of the food-derived mutagen/carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates.

    Snyderwine EG, Buonarati MH, Felton JS, Turteltaub KW.

    Carcinogenesis. 1993 Dec;14(12):2517-22.PMID: 8269621 [PubMed - indexed for MEDLINE]Related articles

    11.

    Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rat and human hepatocytes.

    Langouët S, Paehler A, Welti DH, Kerriguy N, Guillouzo A, Turesky RJ.

    Carcinogenesis. 2002 Jan;23(1):115-22.PMID: 11756232 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    The direct glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) by human and rabbit liver microsomes.

    Styczynski PB, Blackmon RC, Groopman JD, Kensler TW.

    Chem Res Toxicol. 1993 Nov-Dec;6(6):846-51.PMID: 8117924 [PubMed - indexed for MEDLINE]Related articles

    13.

    Formation of a glutathione conjugate and a semistable transportable glucuronide conjugate of N2-oxidized species of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat liver.

    Alexander J, Wallin H, Rossland OJ, Solberg KE, Holme JA, Becher G, Andersson R, Grivas S.

    Carcinogenesis. 1991 Dec;12(12):2239-45.PMID: 1747923 [PubMed - indexed for MEDLINE]Related articles

    14.

    Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice.

    Buonarati MH, Roper M, Morris CJ, Happe JA, Knize MG, Felton JS.

    Carcinogenesis. 1992 Apr;13(4):621-7.PMID: 1576715 [PubMed - indexed for MEDLINE]Related articles

    15.

    The capability of rat colon tissue slices to metabolize the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

    Malfatti MA, Connors MS, Mauthe RJ, Felton JS.

    Cancer Res. 1996 Jun 1;56(11):2550-5.PMID: 8653696 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Deconjugation of N-glucuronide conjugated metabolites with hydrazine hydrate--biomarkers for exposure to the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

    Frandsen H.

    Food Chem Toxicol. 2007 May;45(5):863-70. Epub 2006 Nov 16.PMID: 17184892 [PubMed - indexed for MEDLINE]Related articles

    17.

    Metabolism of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by lactating Fischer 344 rats and their nursing pups.

    Davis CD, Ghoshal A, Schut HA, Snyderwine EG.

    J Natl Cancer Inst. 1994 Jul 20;86(14):1065-70.PMID: 8021955 [PubMed - indexed for MEDLINE]Related articles

    18.

    Uptake of the food-derived heterocyclic amine carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and its N-hydroxy metabolite into rat pancreatic acini and hepatocytes in vitro.

    Butcher NJ, Minchin RF, Kadlubar FF, Ilett KF.

    Carcinogenesis. 1996 Apr;17(4):889-92.PMID: 8625507 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    4-(2-amino-1-methylimidazo[4,5-b]pyrid-6-yl)phenyl sulfate--a major metabolite of the food mutagen 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP) in the rat.

    Alexander J, Wallin H, Holme JA, Becher G.

    Carcinogenesis. 1989 Aug;10(8):1543-7.PMID: 2752529 [PubMed - indexed for MEDLINE]Related articles

    20.

    Identification of urine metabolites of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans.

    Kulp KS, Knize MG, Malfatti MA, Salmon CP, Felton JS.

    Carcinogenesis. 2000 Nov;21(11):2065-72.PMID: 11062169 [PubMed - indexed for MEDLINE]Related articlesFree article

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