PubMed

Evidence of autoimmune-related effects of trichloroethylene exposure from studies in mice and humans.

Cooper GS, Makris SL, Nietert PJ, Jinot J.

Environ Health Perspect. 2009 May;117(5):696-702. Epub 2009 Jan 9. Review.PMID: 19479009 [PubMed - indexed for MEDLINE]Related articlesFree article

Delineating liver events in trichloroethylene-induced autoimmune hepatitis.

Gilbert KM, Przybyla B, Pumford NR, Han T, Fuscoe J, Schnackenberg LK, Holland RD, Doss JC, Macmillan-Crow LA, Blossom SJ.

Chem Res Toxicol. 2009 Apr;22(4):626-32.PMID: 19254012 [PubMed - indexed for MEDLINE]Related articles

CD4(+) T-cell activation and induction of autoimmune hepatitis following trichloroethylene treatment in MRL+/+ mice.

Griffin JM, Gilbert KM, Lamps LW, Pumford NR.

Toxicol Sci. 2000 Oct;57(2):345-52.PMID: 11006364 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic exposure to trichloroethene causes early onset of SLE-like disease in female MRL +/+ mice.

Cai P, König R, Boor PJ, Kondraganti S, Kaphalia BS, Khan MF, Ansari GA.

Toxicol Appl Pharmacol. 2008 Apr 1;228(1):68-75. Epub 2007 Dec 14.PMID: 18234256 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic exposure to a trichloroethylene metabolite in autoimmune-prone MRL+/+ mice promotes immune modulation and alopecia.

Blossom SJ, Doss JC, Gilbert KM.

Toxicol Sci. 2007 Feb;95(2):401-11. Epub 2006 Oct 31.PMID: 17077186 [PubMed - indexed for MEDLINE]Related articlesFree article

Developmental exposure to trichloroethylene promotes CD4+ T cell differentiation and hyperactivity in association with oxidative stress and neurobehavioral deficits in MRL+/+ mice.

Blossom SJ, Doss JC, Hennings LJ, Jernigan S, Melnyk S, James SJ.

Toxicol Appl Pharmacol. 2008 Sep 15;231(3):344-53. Epub 2008 May 20.PMID: 18579175 [PubMed - indexed for MEDLINE]Related articles

Lipid peroxidation-derived aldehyde-protein adducts contribute to trichloroethene-mediated autoimmunity via activation of CD4+ T cells.

Wang G, König R, Ansari GA, Khan MF.

Free Radic Biol Med. 2008 Apr 1;44(7):1475-82. Epub 2008 Jan 26.PMID: 18267128 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative and nitrosative stress in trichloroethene-mediated autoimmune response.

Wang G, Cai P, Ansari GA, Khan MF.

Toxicology. 2007 Jan 18;229(3):186-93. Epub 2006 Oct 29.PMID: 17123686 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of lipid peroxidation-derived aldehyde-protein adducts in autoimmunity mediated by trichloroethene.

Wang G, Ansari GA, Khan MF.

J Toxicol Environ Health A. 2007 Dec;70(23):1977-85.PMID: 17966069 [PubMed - indexed for MEDLINE]Related articles

Environmental Contaminant Trichloroethylene Promotes Autoimmune Disease and Inhibits T-cell Apoptosis in MRL(+/+) Mice.

Gilbert KM, Pumford NR, Blossom SJ.

J Immunotoxicol. 2006 Dec 1;3(4):263-7.PMID: 18958707 [PubMed - in process]Related articles

Assessment of trichloroethylene (TCE) exposure in murine strains genetically-prone and non-prone to develop autoimmune disease.

Keil DE, Peden-Adams MM, Wallace S, Ruiz P, Gilkeson GS.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2009 Apr;44(5):443-53.PMID: 19241258 [PubMed - indexed for MEDLINE]Related articles

Lifetime exposure to trichloroethylene (TCE) does not accelerate autoimmune disease in MRL +/+ mice.

Peden-Adams MM, Eudaly JG, Lee AM, Miller J, Keil DE, Gilkeson GS.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2008 Oct;43(12):1402-9.PMID: 18780217 [PubMed - indexed for MEDLINE]Related articles

Trichloroethylene Does Not Accelerate Autoimmune Diabetes in NOD Mice.

Ravel G, Christ M, Perron-Lepage MF, Condevaux F, Descotes J.

J Immunotoxicol. 2005 Jul 1;1(3):141-8.PMID: 18958647 [PubMed - in process]Related articles

Increased nitration and carbonylation of proteins in MRL+/+ mice exposed to trichloroethene: potential role of protein oxidation in autoimmunity.

Wang G, Wang J, Ma H, Khan MF.

Toxicol Appl Pharmacol. 2009 Jun 1;237(2):188-95. Epub 2009 Mar 28.PMID: 19332086 [PubMed - indexed for MEDLINE]Related articles

Occupational trichloroethylene exposure and non-Hodgkin's lymphoma: a meta-analysis and review.

Mandel JH, Kelsh MA, Mink PJ, Alexander DD, Kalmes RM, Weingart M, Yost L, Goodman M.

Occup Environ Med. 2006 Sep;63(9):597-607. Epub 2006 Apr 27. Review.PMID: 16644896 [PubMed - indexed for MEDLINE]Related articlesFree article

Comments on "Lifetime exposure to trichloroethylene (TCE) does not accelerate autoimmune disease in MRL+/- mice.

Gilbert KM, Blossom SJ, Pumford NR.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2009 Jan;44(1):116; author reply 117-22. No abstract available. PMID: 19085602 [PubMed - indexed for MEDLINE]Related articles

A clearer view of TCE: evidence supports autoimmune link.

Weinhold B.

Environ Health Perspect. 2009 May;117(5):A210. No abstract available. PMID: 19478988 [PubMed - indexed for MEDLINE]Related articlesFree article

Trichloroethylene accelerates an autoimmune response by Th1 T cell activation in MRL +/+ mice.

Griffin JM, Blossom SJ, Jackson SK, Gilbert KM, Pumford NR.

Immunopharmacology. 2000 Feb;46(2):123-37.PMID: 10647871 [PubMed - indexed for MEDLINE]Related articles

Trichloroethene-induced autoimmune response in female MRL +/+ mice.

Khan MF, Kaphalia BS, Prabhakar BS, Kanz MF, Ansari GA.

Toxicol Appl Pharmacol. 1995 Sep;134(1):155-60.PMID: 7676450 [PubMed - indexed for MEDLINE]Related articles

Immunotoxicity of trichloroethylene: a study with MRL-lpr/lpr mice.

Kaneko T, Saegusa M, Tasaka K, Sato A.

J Appl Toxicol. 2000 Nov-Dec;20(6):471-5.PMID: 11180269 [PubMed - indexed for MEDLINE]Related articles