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Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production.
Lambrot R, Muczynski V, Lécureuil C, Angenard G, Coffigny H, Pairault C, Moison D, Frydman R, Habert R, Rouiller-Fabre V.
Environ Health Perspect. 2009 Jan;117(1):32-7. Epub 2008 Sep 9.PMID: 19165384 [PubMed - indexed for MEDLINE]Related articlesFree article
Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro.
Chauvigné F, Menuet A, Lesné L, Chagnon MC, Chevrier C, Regnier JF, Angerer J, Jégou B.
Environ Health Perspect. 2009 Apr;117(4):515-21. Epub 2008 Dec 1.PMID: 19440488 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of monobutyl and di(n-butyl) phthalate in vitro on steroidogenesis and Leydig cell aggregation in fetal testis explants from the rat: comparison with effects in vivo in the fetal rat and neonatal marmoset and in vitro in the human.
Hallmark N, Walker M, McKinnell C, Mahood IK, Scott H, Bayne R, Coutts S, Anderson RA, Greig I, Morris K, Sharpe RM.
Environ Health Perspect. 2007 Mar;115(3):390-6. Epub 2006 Dec 19.PMID: 17431488 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of mono-(2-ethylhexyl) phthalate on fetal and neonatal rat testis organ cultures.
Li H, Kim KH.
Biol Reprod. 2003 Dec;69(6):1964-72. Epub 2003 Aug 6.PMID: 12904314 [PubMed - indexed for MEDLINE]Related articlesFree article
Use of organ culture to study the human fetal testis development: effect of retinoic acid.
Lambrot R, Coffigny H, Pairault C, Donnadieu AC, Frydman R, Habert R, Rouiller-Fabre V.
J Clin Endocrinol Metab. 2006 Jul;91(7):2696-703. Epub 2006 Apr 18.PMID: 16621909 [PubMed - indexed for MEDLINE]Related articlesFree article
A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner.
Howdeshell KL, Wilson VS, Furr J, Lambright CR, Rider CV, Blystone CR, Hotchkiss AK, Gray LE Jr.
Toxicol Sci. 2008 Sep;105(1):153-65. Epub 2008 Apr 14.PMID: 18411233 [PubMed - indexed for MEDLINE]Related articlesFree article
Effect of fetal or neonatal exposure to monobutyl phthalate (MBP) on testicular development and function in the marmoset.
McKinnell C, Mitchell RT, Walker M, Morris K, Kelnar CJ, Wallace WH, Sharpe RM.
Hum Reprod. 2009 Sep;24(9):2244-54. Epub 2009 Jun 2.PMID: 19491204 [PubMed - indexed for MEDLINE]Related articlesFree article
[Development and regulations of testicular functions in the human foetus]
Rouiller-Fabre V, Lambrot R, Muczynski V, Coffigny H, Lécureuil C, Pairault C, Bakalska M, Courtot AM, Frydman R, Habert R.
Gynecol Obstet Fertil. 2008 Sep;36(9):898-907. Epub 2008 Aug 20. Review. French. PMID: 18718803 [PubMed - indexed for MEDLINE]Related articles
Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis.
Wilson VS, Lambright C, Furr J, Ostby J, Wood C, Held G, Gray LE Jr.
Toxicol Lett. 2004 Feb 2;146(3):207-15.PMID: 14687758 [PubMed - indexed for MEDLINE]Related articles
Differential effects of phthalates on the testis and the liver.
Bhattacharya N, Dufour JM, Vo MN, Okita J, Okita R, Kim KH.
Biol Reprod. 2005 Mar;72(3):745-54. Epub 2004 Nov 24.PMID: 15564602 [PubMed - indexed for MEDLINE]Related articlesFree article
High radiosensitivity of germ cells in human male fetus.
Lambrot R, Coffigny H, Pairault C, Lécureuil C, Frydman R, Habert R, Rouiller-Fabre V.
J Clin Endocrinol Metab. 2007 Jul;92(7):2632-9. Epub 2007 Apr 24.PMID: 17456577 [PubMed - indexed for MEDLINE]Related articlesFree article
Effect of some phthalate esters and other testicular toxins on primary cultures of testicular cells.
Gray TJ, Beamand JA.
Food Chem Toxicol. 1984 Feb;22(2):123-31.PMID: 6538161 [PubMed - indexed for MEDLINE]Related articles
Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture.
Lassurguère J, Livera G, Habert R, Jégou B.
Toxicol Sci. 2003 May;73(1):160-9. Epub 2003 Mar 25.PMID: 12657744 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of relatively low levels of mono-(2-ethylhexyl) phthalate on cocultured Sertoli cells and gonocytes from neonatal rats.
Li LH, Jester WF Jr, Orth JM.
Toxicol Appl Pharmacol. 1998 Dec;153(2):258-65.PMID: 9878596 [PubMed - indexed for MEDLINE]Related articles
Long-term effects of intrauterine exposure to mono-n-butyl phthalate on the reproductive function of postnatal rats.
Kai H, Shono T, Tajiri T, Suita S.
J Pediatr Surg. 2005 Feb;40(2):429-33.PMID: 15750943 [PubMed - indexed for MEDLINE]Related articles
Expression and effect of insulin-like growth factor I on rat fetal Leydig cell function and differentiation.
Rouiller-Fabre V, Lecref L, Gautier C, Saez JM, Habert R.
Endocrinology. 1998 Jun;139(6):2926-34.PMID: 9607803 [PubMed - indexed for MEDLINE]Related articlesFree article
Fetal mouse phthalate exposure shows that Gonocyte multinucleation is not associated with decreased testicular testosterone.
Gaido KW, Hensley JB, Liu D, Wallace DG, Borghoff S, Johnson KJ, Hall SJ, Boekelheide K.
Toxicol Sci. 2007 Jun;97(2):491-503. Epub 2007 Mar 14.PMID: 17361019 [PubMed - indexed for MEDLINE]Related articlesFree article
Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalate.
Lehmann KP, Phillips S, Sar M, Foster PM, Gaido KW.
Toxicol Sci. 2004 Sep;81(1):60-8. Epub 2004 May 12.PMID: 15141095 [PubMed - indexed for MEDLINE]Related articlesFree article
Multiple effects of retinoids on the development of Sertoli, germ, and Leydig cells of fetal and neonatal rat testis in culture.
Livera G, Rouiller-Fabre V, Durand P, Habert R.
Biol Reprod. 2000 May;62(5):1303-14.PMID: 10775181 [PubMed - indexed for MEDLINE]Related articlesFree article
Transforming growth factor beta1 inhibits steroidogenesis in dispersed fetal testicular cells in culture.
Gautier C, Levacher C, Saez JM, Habert R.
Mol Cell Endocrinol. 1997 Jul 4;131(1):21-30.PMID: 9256360 [PubMed - indexed for MEDLINE]Related articles
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