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    Results: 1 to 20 of 183

    1.

    Identification of genes implicated in methapyrilene-induced hepatotoxicity by comparing differential gene expression in target and nontarget tissue.

    Auman JT, Chou J, Gerrish K, Huang Q, Jayadev S, Blanchard K, Paules RS.

    Environ Health Perspect. 2007 Apr;115(4):572-8. Epub 2007 Jan 17.PMID: 17450226 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations.

    Hamadeh HK, Knight BL, Haugen AC, Sieber S, Amin RP, Bushel PR, Stoll R, Blanchard K, Jayadev S, Tennant RW, Cunningham ML, Afshari CA, Paules RS.

    Toxicol Pathol. 2002 Jul-Aug;30(4):470-82.PMID: 12187938 [PubMed - indexed for MEDLINE]Related articles

    3.

    Systems toxicology: integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat.

    Craig A, Sidaway J, Holmes E, Orton T, Jackson D, Rowlinson R, Nickson J, Tonge R, Wilson I, Nicholson J.

    J Proteome Res. 2006 Jul;5(7):1586-601.PMID: 16823966 [PubMed - indexed for MEDLINE]Related articles

    4.

    Gene expression profiling of methapyrilene-induced hepatotoxicity in rat.

    Uehara T, Kiyosawa N, Hirode M, Omura K, Shimizu T, Ono A, Mizukawa Y, Miyagishima T, Nagao T, Urushidani T.

    J Toxicol Sci. 2008 Feb;33(1):37-50.PMID: 18303183 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Interlaboratory evaluation of rat hepatic gene expression changes induced by methapyrilene.

    Waring JF, Ulrich RG, Flint N, Morfitt D, Kalkuhl A, Staedtler F, Lawton M, Beekman JM, Suter L.

    Environ Health Perspect. 2004 Mar;112(4):439-48.PMID: 15033593 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    D-Serine exposure resulted in gene expression changes indicative of activation of fibrogenic pathways and down-regulation of energy metabolism and oxidative stress response.

    Soto A, DelRaso NJ, Schlager JJ, Chan VT.

    Toxicology. 2008 Jan 14;243(1-2):177-92. Epub 2007 Oct 23.PMID: 18061331 [PubMed - indexed for MEDLINE]Related articles

    7.

    Gene expression analysis of the hepatotoxicant methapyrilene in primary rat hepatocytes: an interlaboratory study.

    Beekman JM, Boess F, Hildebrand H, Kalkuhl A, Suter L.

    Environ Health Perspect. 2006 Jan;114(1):92-9.PMID: 16393664 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Dose-responses in rat hepatic protein modification and expression following exposure to the rat hepatocarcinogen methapyrilene.

    Richardson FC, Horn DM, Anderson NL.

    Carcinogenesis. 1994 Feb;15(2):325-9.PMID: 8313526 [PubMed - indexed for MEDLINE]Related articles

    9.

    Extracting gene expression patterns and identifying co-expressed genes from microarray data reveals biologically responsive processes.

    Chou JW, Zhou T, Kaufmann WK, Paules RS, Bushel PR.

    BMC Bioinformatics. 2007 Nov 2;8:427.PMID: 17980031 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Quantitative PCR deconstruction of discrepancies between results reported by different hybridization platforms.

    Goodsaid FM, Smith RJ, Rosenblum IY.

    Environ Health Perspect. 2004 Mar;112(4):456-60.PMID: 15033595 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Overview of an interlaboratory collaboration on evaluating the effects of model hepatotoxicants on hepatic gene expression.

    Ulrich RG, Rockett JC, Gibson GG, Pettit SD.

    Environ Health Perspect. 2004 Mar;112(4):423-7.PMID: 15033591 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Protein expression analysis of drug-mediated hepatotoxicity in the Sprague-Dawley rat.

    Man WJ, White IR, Bryant D, Bugelski P, Camilleri P, Cutler P, Heald G, Lord PG, Wood J, Kramer K.

    Proteomics. 2002 Nov;2(11):1577-85.PMID: 12442256 [PubMed - indexed for MEDLINE]Related articles

    13.

    Acute hepatotoxicity: a predictive model based on focused illumina microarrays.

    Zidek N, Hellmann J, Kramer PJ, Hewitt PG.

    Toxicol Sci. 2007 Sep;99(1):289-302. Epub 2007 May 22.PMID: 17522070 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Gene expression profiling reveals multiple toxicity endpoints induced by hepatotoxicants.

    Huang Q, Jin X, Gaillard ET, Knight BL, Pack FD, Stoltz JH, Jayadev S, Blanchard KT.

    Mutat Res. 2004 May 18;549(1-2):147-67.PMID: 15120968 [PubMed - indexed for MEDLINE]Related articles

    15.

    Effects of induction and inhibition of cytochromes P450 on the hepatotoxicity of methapyrilene.

    Ratra GS, Cottrell S, Powell CJ.

    Toxicol Sci. 1998 Nov;46(1):185-96.PMID: 9928682 [PubMed - indexed for MEDLINE]Related articles

    16.

    Gene expression profiling of rat livers reveals indicators of potential adverse effects.

    Heinloth AN, Irwin RD, Boorman GA, Nettesheim P, Fannin RD, Sieber SO, Snell ML, Tucker CJ, Li L, Travlos GS, Vansant G, Blackshear PE, Tennant RW, Cunningham ML, Paules RS.

    Toxicol Sci. 2004 Jul;80(1):193-202. Epub 2004 Apr 14.PMID: 15084756 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Clofibrate-induced gene expression changes in rat liver: a cross-laboratory analysis using membrane cDNA arrays.

    Baker VA, Harries HM, Waring JF, Duggan CM, Ni HA, Jolly RA, Yoon LW, De Souza AT, Schmid JE, Brown RH, Ulrich RG, Rockett JC.

    Environ Health Perspect. 2004 Mar;112(4):428-38.PMID: 15033592 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Relationship between hepatic gene expression profiles and hepatotoxicity in five typical hepatotoxicant-administered rats.

    Minami K, Saito T, Narahara M, Tomita H, Kato H, Sugiyama H, Katoh M, Nakajima M, Yokoi T.

    Toxicol Sci. 2005 Sep;87(1):296-305. Epub 2005 Jun 23.PMID: 15976192 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Effects of acetaminophen on hepatic gene expression in mice.

    Jeong SY, Lim JS, Park HJ, Cho JW, Rana SV, Yoon S.

    Physiol Chem Phys Med NMR. 2006;38(2):77-83.PMID: 18472468 [PubMed - indexed for MEDLINE]Related articles

    20.

    Toxicogenomic analysis of gene expression changes in rat liver after a 28-day oral benzene exposure.

    Heijne WH, Jonker D, Stierum RH, van Ommen B, Groten JP.

    Mutat Res. 2005 Aug 4;575(1-2):85-101.PMID: 15878777 [PubMed - indexed for MEDLINE]Related articles

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